Alessandro is Director of Engineering at the Raphael Center for Neurorestoration at Thomas Jefferson University, where he leads a multidisciplinary team developing neurotechnology for individuals with neuromuscular disorders. His work spans brain-computer interfaces, neural signal processing, medical device development, and applied machine learning. He has contributed to devices reaching clinical feasibility trials, including NuroSleeve and RISES, and has authored 40+ peer-reviewed publications. His current research interests include closed-loop neural interfaces, in-vitro multi-electrode array studies of reinforcement-learning signaling in cultured neural networks, and translational neurorestorative engineering.