John Bertram

Dr. John Bertram

orcid

Research Focus & Metrics

Academic Career Length

45Years (1982-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2003 in Kidney International
Verified
Journal Article
Closed access
MHMichael Hughson
Michael Hughson
AFAlton B. Farris
Alton B. Farris
RDRebecca Douglas-Denton
Rebecca Douglas-Denton
WHWendy E Hoy
Wendy E Hoy
JBJohn Bertram
John Bertram

1 September 2011 in Pediatric Nephrology
Verified
Journal Article
Closed access
PDF file
JBJohn Bertram
John Bertram
RDRebecca N. Douglas-Denton
Rebecca N. Douglas-Denton
BDBoucar Diouf
Boucar Diouf
MHMichael D. Hughson
Michael D. Hughson
WHWendy E Hoy
Wendy E Hoy

1 July 2013 in The Lancet
Verified
Journal Article
Closed access
VLValerie A Luyckx
Valerie A Luyckx
JBJohn Bertram
John Bertram
BBBarry M Brenner
Barry M Brenner
CFCaroline Fall
Caroline Fall
WHWendy E Hoy
Wendy E Hoy
BVBjorn E Vikse
Bjorn E Vikse

1 February 2003 in Kidney International
Verified
Journal Article
Closed access
WHWendy E Hoy
Wendy E Hoy
RDRebecca N. Douglas-Denton
Rebecca N. Douglas-Denton
MHMichael D. Hughson
Michael D. Hughson
ACAlan Cass
Alan Cass
KJKelli Johnson
Kelli Johnson
JBJohn Bertram
John Bertram


1 July 2011 in Journal of the American Society of Nephrology
Verified
Journal Article
Open access
PDF file
MSMegan R. Sutherland
Megan R. Sutherland
LGLina Gubhaju
Lina Gubhaju
LMLynette Moore
Lynette Moore
AKAlison L. Kent
Alison L. Kent
JDJane Dahlstrom
Jane Dahlstrom
MBM. Jane Black
M. Jane Black
Nephrogenesis is ongoing at the time of birth for the majority of preterm infants, but whether postnatal renal development follows a similar trajectory to normal in utero growth is unknown. Here, we examined tissue collected at autopsy from 28 kidneys from preterm neonates, whose postnatal survival ranged from 2 to 68 days, including 6 that had restricted intrauterine growth. In addition, we examined kidneys from 32 still-born gestational controls. We assessed the width of the nephrogenic zone, number of glomerular generations, cross-sectional area of the renal corpuscle, and glomerular maturity and morphology. Renal maturation accelerated after preterm birth, with an increased number of glomerular generations and a decreased width of the nephrogenic zone in the kidneys of preterm neonates. Of particular concern, compared with gestational controls, preterm kidneys had a greater percentage of morphologically abnormal glomeruli and a significantly larger cross-sectional area of the renal corpuscle, suggestive of renal hyperfiltration. These observations suggest that the preterm kidney may have fewer functional nephrons, thereby increasing vulnerability to impaired renal function in both the early postnatal period and later in life.