José Mauricio López-Romero

Dr. José Mauricio López-Romero

orcid

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 March 2021 in Materials
Verified
Journal Article
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JAJosé Luis Reyes Araiza
José Luis Reyes Araiza
JPJorge Pineda
Jorge Pineda
JLJosé Mauricio López-Romero
José Mauricio López-Romero
JGJosé Ramón Gasca-Tirado
José Ramón Gasca-Tirado
MCMoises Arroyo Contreras
Moises Arroyo Contreras
AMAlejandro Manzano-Ramirez
Alejandro Manzano-Ramirez
The energy sector is one of the fields of interest for different nations around the world. Due to the current fossil fuel crisis, the scientific community develops new energy-saving experiences to address this concern. Buildings are one of the elements of higher energy consumption, so the generation of knowledge and technological development may offer solutions to this energy demand, which are more than welcome. Phase change materials (PCMs) included in building elements such as wall panels, blocks, panels or coatings, for heating and cooling applications have been shown, when heating, to increase the heat storage capacity by absorbing heat as latent heat. Therefore, the use of latent heat storage systems using phase change materials (PCMs) has been investigated within the last two decades. In the present review, the macro and micro encapsulation methods for construction materials are reviewed, the former being the most viable method of inclusion of PCMs in construction elements. In addition, based on the analysis of the existing papers on the encapsulation process of PCMs, the importance to pay more attention to the bio-based PCMs is shown, since more research is needed to process such PCMs. To determine its thermophysical and mechanical behavior at the micro and macro levels, in order to see the feasibility of substituting petroleum-based PCMs with a more environmentally friendly bio-based one, a section devoted to the excellent PCM with lightweight aggregate (PCM-LWA concrete) is presented due to the lack of description given in other reviews.

28 September 2022 in Pharmaceutics
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Journal Article
Open access
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KSKaren M. Soto
Karen M. Soto
Ivan Luzardo-OcampoIvan Luzardo-Ocampo
Ivan Luzardo-Ocampo
JLJosé Mauricio López-Romero
José Mauricio López-Romero
SMSandra Mendoza
Sandra Mendoza
GPGuadalupe Guadalupe Flavia Loarca Loarca Piña
Guadalupe Guadalupe Flavia Loarca Loarca Piña
AMAlejandro Manzano-Ramirez
Alejandro Manzano-Ramirez
Gold nanoparticles (AuNPs) are promising nanomaterials exhibiting anti-cancer effects. Green AuNPs synthesis using plant extracts can be used to achieve stable and beneficial nanoparticles due to their content of bioactive compounds. This research aimed to synthesize and evaluate the antiproliferative and caspase-3 activity induction of green AuNPs synthesized with common mullein (V. thapsus) flowers (AuNPsME) and castor bean (R. communis) leaves (AuNPsCE) ethanolic extracts in human HT29 and SW480 colorectal cancer cells. Their effect was compared with chemically synthesized AuNPs (AuNPsCS). The extracts mainly contained p-coumaric acid (71.88–79.93 µg/g), ferulic acid (19.07–310.71 µg/g), and rutin (8.14–13.31 µg/g). The obtained nanoparticles presented typical FT-IR bands confirming the inclusion of polyphenols from V. thapsus and R. communis and spherical/quasi-spherical morphologies with diameters in the 20.06–37.14 nm range. The nanoparticles (20–200 µg/mL) showed antiproliferative effects in both cell lines, with AuNPsCE being the most potent (IC50 HT29: 110.10 and IC50SW480: 64.57 µg/mL). The AuNPsCS showed the lowest intracellular reactive oxygen species (ROS) generation in SW480 cells. All treatments induced caspase 3/7 activity to a similar or greater extent than 30 mM H2O2-treated cells. Results indicated the suitability of V. thapsus and R. communis extracts to synthesize AuNPs, displaying a stronger antiproliferative effect than AuNPsCS.

23 October 2022
Verified
Book Chapter
Closed access
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MRMayra Alejandra Rivera-Ruiz
Mayra Alejandra Rivera-Ruiz
AMAndres Mendez-Vazquez
Andres Mendez-Vazquez
JLJosé Mauricio López-Romero
José Mauricio López-Romero

23 March 2023 in Pharmaceuticals
Verified
Journal Article
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KSKaren M. Soto
Karen M. Soto
José de Jesús Pérez BuenoJosé de Jesús Pérez Bueno
José de Jesús Pérez Bueno
MLMaria Luisa Mendoza López
Maria Luisa Mendoza López
MAMiguel Apátiga-Castro
Miguel Apátiga-Castro
JLJosé Mauricio López-Romero
José Mauricio López-Romero
AMAlejandro Manzano-Ramirez
Alejandro Manzano-Ramirez
Traditional medicine in Latin America and mainly in Mexico represents an essential alternative for treating different diseases. The use of plants as medicine is the product of a rich cultural tradition of the indigenous peoples, in which a great variety of species are used for the treatment of gastrointestinal, respiratory, and mental diseases and some other sicknesses; the therapeutic efficacy that they possess is due to the properties that derive from the active ingredients of plants principally antioxidants, such as phenolic compounds, flavonoids, terpenes, and tannins. An antioxidant is a substance that, at low concentrations, delays or prevents substrate oxidation through the exchange of electrons. Different methods are used to determine the antioxidant activity and the most commonly used are described in the review. Cancer is a disease in which some cells multiply uncontrollably and spread to other parts of the body, a process known as metastasis. These cells can lead to the formation of tumors, which are lumps of tissue that can be cancerous (malignant) or noncancerous (benign). Generally, the treatment of this disease consists of surgery, radiotherapy, or chemotherapy, which have side effects that decrease the quality of life of patients, so new treatments, focusing on natural resources such as plants, can be developed. This review aims to gather scientific evidence on the antioxidant compounds present in plants used in traditional Mexican medicine, specifically as antitumor treatment in the most common cancer types worldwide (e.g., breast, liver, and colorectal cancer).

23 December 2016 in Entropy
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Journal Article
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Luis A. Lizama-PerezLuis A. Lizama-Perez
Luis A. Lizama-Perez
JLJosé Mauricio López-Romero
José Mauricio López-Romero
ELEduardo De Carlos López
Eduardo De Carlos López
Despite the unconditionally secure theory of the Quantum Key Distribution (Q K D), several attacks have been successfully implemented against commercial Q K D systems. Those systems have exhibited some flaws, as the secret key rate of corresponding protocols remains unaltered, while the eavesdropper obtains the entire secret key. We propose the negative acknowledgment state quantum key distribution protocol as a novel protocol capable of detecting the eavesdropping activity of the Intercept Resend with Faked Sates (I R F S) attack without requiring additional optical components different from the B B 84 protocol because the system can be implemented as a high software module. In this approach, the transmitter interleaves pairs of quantum states, referred to here as parallel and orthogonal states, while the receiver uses active basis selection.

Verified
Journal Article
Open access
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KSKaren M. Soto
Karen M. Soto
AGAngelica Gódinez-Oviedo
Angelica Gódinez-Oviedo
ARAdriana Romo-Pérez
Adriana Romo-Pérez
SMSandra Mendoza
Sandra Mendoza
JLJosé Mauricio López-Romero
José Mauricio López-Romero
AMAlejandro Manzano-Ramirez
Alejandro Manzano-Ramirez
Green synthesis of gold nanoparticles (AuNPs) provides a significantly eco-friendly and low-impact counterpart to conventional chemical methods. In the present study, we synthesized gold nanoparticles using Schinus molle (P-AuNPs) aqueous extract as a reducing and stabilizing agent. The obtained nanoparticles were then stabilized by another biocompatible agent, the chiral amino acids L-cysteine (L-Cys-AuNPs) and D-cysteine (D-Cys-AuNPs), to estimate the potential of the surface modification for enhancing AuNPs surface chemistry and antimicrobial action. The synthesized gold nanoparticles were confirmed by UV-Vis spectroscopy, FTIR, XRD, and circular dichroism to validate their formation, crystalline structure, surface properties, and chirality. Physicochemical characterization confirmed the formation of crystalline AuNPs with size and morphology modulated by chiral functionalization. TEM and DLS analyses showed that L-cysteine-functionalized AuNPs were smaller and more uniform, while FTIR and circular dichroism spectroscopy confirmed surface binding and the induction of optical activity, respectively. L-Cys-AuNPs exhibited the highest antimicrobial efficacy against a broad spectrum of microorganisms, including Escherichia coli, Salmonella enterica, Listeria monocytogenes, Staphylococcus aureus, Staphylococcus epidermidis, and, notably, Candida albicans. L-Cys-AuNPs showed the lowest MIC and MBC values, highlighting the synergistic effect of chirality on biological performance. These findings suggest that L-cysteine surface engineering significantly enhances the therapeutic potential of AuNPs, particularly in combating drug-resistant fungal pathogens such as C. albicans. This research paves the way for the development of next-generation antimicrobial agents, reinforcing the relevance of green nanotechnology in the field of materials science and nanotechnology.