With the growing popularity of cryptocurrencies, detecting potential market manipulation and fraudulent activities has become crucial for maintaining market integrity. In this study, we aim to detect anomalous Bitcoin transactions using an integrated approach by combining clustering techniques with statistical outlier detection. More specifically, anomalies were detected using three approaches: a distance-based method, flagging points with distances greater than the 95th percentile from their cluster centers; a statistical method, identifying transactions with any feature having an absolute Z-score greater than 3; and a hybrid approach, where transactions flagged by either method were considered anomalous. Using sample subset Bitcoin transaction data from 2015, our results showed that the combined approach was able to achieve the best performance with a total of 6492 (6.61%) detected anomalous transactions out of a total of 98,151 transactions.