OBJECTIVE. The aim of this study was to investigate dynamic contrast-enhanced MRI (DCE-MRI) for the noninvasive measurement of bladder cancer angiogenesis by correlation with microvessel density, histologic grade, and tumor staging, and to predict the outcome of local recurrence.MATERIALS AND METHODS. Twenty-four patients with bladder cancer were examined using DCE-MRI. Hemodynamic parameters obtained by DCE-MRI included peak time enhancement in the first minute (Emax/1) after contrast administration, second minute (Emax/2), third minute (Emax/3), fourth minute (Emax/4), and fifth minute (Emax/5), and the steepest slope. Microvessel density was identified by immunostaining of endothelial cells using FVIII-related antigen. The Mann-Whitney U test, multivariate discriminant analysis, Spearman's correlation coefficient, and analysis of variance were used for statistical analysis.RESULTS. Correlation was seen between DCE-MRI parameters (Emax/1 and steepest slope) and microvessel density (p < 0.05). Emax/1 and...

The goal of this research was to correlate dynamic magnetic resonance (MR) mammographic contrast enhancement and microvessel densities in breast masses. Forty‐six female patients with brea...