In this study, we propose a digital domain TDI-CMOS dynamic imaging method based on minimum search domain alignment, which consists of five steps: image-motion vector computation, image jitter estimation, feature pair matching, global displacement estimation, and TDI accumulation. To solve the challenge of matching feature point pairs in dark and low-contrast images, our method first optimizes the size and position of the search box using an image motion compensation mathematical model and a satellite platform jitter model. Then, the feature point pairs that best match the extracted feature points of the reference frame are identified within the search box of the target frame. After that, a kernel density estimation algorithm is proposed for calculating the displacement probability density of each feature point pair to fit the actual displacement between two frames. Finally, we align and superimpose all the frames in the digital domain to generate a delayed integral image. Experimental results show that this method greatly improves the alignment speed and accuracy of dark and low-contrast images during dynamic imaging. It effectively mitigates the effects of image motion and jitter from the spatial camera, and the fitted global image motion error is kept below 0.01 pixels, which is compensated to improve the MTF coefficient of the image motion and jitter link to 0.68, thus improving the imaging quality of TDI.