Objective: Telerehabilitation is a rapidly growing area within telehealth, providing clinical rehabilitation services through telecommunication technologies to enhance accessibility, improve care quality, and support patient functionality. Pediatric motor rehabilitation has gained increasing recognition for its vital role in promoting neuromotor development, coordination, and independence in children with congenital or acquired motor disabilities. This systematic review analyzed home-based telerehabilitation interventions for pediatric neurological motor disorders, from the neonatal period onward, aiming to outline current trends and future directions. Methods: A comprehensive search was conducted across Medline, EBSCO, and Web of Science, covering records up to February 2025. Peer-reviewed articles were included without restrictions on study design. The focus was on pediatric and adolescent populations with neurodevelopmental or neuromuscular disorders undergoing telerehabilitation or remote rehabilitative interventions. Results: The findings support the potential efficacy of tele-neurorehabilitation in improving motor outcomes, with promising results for children with cerebral palsy and hemiplegia. Interventions were shown to enhance motor function (SMD = 0.48; 95% CI: 0.23 to 0.72), range of motion (SMD = 0.31; 95% CI: 0.11 to 0.51), and walking ability (SMD = 0.25; 95% CI: 0.03 to 0.46), suggesting that remote rehabilitation can be an effective complement or alternative to traditional in-person therapy in pediatric care. Moreover, beyond functional improvements, several studies reported positive effects on children's quality of life, highlighting the broader psychosocial benefits of remote interventions. Conclusions: These results underscore the holistic value of telerehabilitation, reinforcing its role as a comprehensive and accessible strategy in pediatric rehabilitation services. Multidimensional assessments are essential to capture the broader benefits of telerehabilitation and to guide the development of more holistic, child- and family-centered care models.

Background: The growing burden of chronic illnesses calls for integrated and sustainable models of Primary Healthcare (PHC) that emphasize health promotion and patient-centered care. Interprofessional collaboration between General Practitioners (GPs) and Family and Community Nurses (FCNs) is a strategic approach to enhancing continuity of care and supporting individuals in adopting healthy behaviors across the trajectory of chronic conditions. This study aims to explore the experiences and perspectives of GPs and FCNs in Italy, with the goal of identifying the barriers, enablers, and transformative dynamics that can inform future PHC models. Methods: A qualitative study was conducted with four focus groups with 21 participants (8 GPs and 13 FCNs) from three Italian regions, carried out between March and November 2023. Data were analyzed using Reflexive Thematic Analysis (RTA) following Braun and Clarke’s framework. Ethical approval was obtained from the University of Parma (Protocol No. 0266537—21 October 2022). Results: Four themes and sixteen subthemes were identified: (1) barriers to effective collaboration (role ambiguity, limited time, structural misalignments); (2) facilitators of collaboration (openness, mutual recognition, shared goals); (3) team-building processes (phases of trust development, shared values, reflective problem-solving); and (4) transformation of work practices (improved patient outcomes, flexible methodologies, integrated care strategies). Conclusions: Interprofessional collaboration between GPs and FCNs enhances the capacity of PHC to address the complex needs of people with chronic conditions. Aligning relational, organizational, and structural factors is essential for sustainable, health-promoting care models. Tailored training, protected time, and shared spaces are critical to foster teamwork, promote patient empowerment, and ensure continuity of care in chronic illness management.

Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that leads to severe functional decline and death, imposing significant physical, emotional, and ethical burdens on patients and healthcare providers. With no curative treatment, ALS care depends on the early and sustained integration of palliative care to address complex and evolving needs. Nurses play a pivotal role in this process, yet their lived experiences remain underexplored. This study aimed to synthesize qualitative evidence on nurses’ experiences in ALS care, with a focus on emotional, ethical, and palliative dimensions. Methods: A meta-synthesis of qualitative studies was conducted using Sandelowski and Barroso’s four-step method. A systematic search across five databases identified eight studies exploring nurses’ experiences with ALS care. Thematic synthesis was applied to extract overarching patterns. Results: Three core themes emerged: (1) Relational Dimension: From challenges to empathy and Trust and mistrust—emphasizing communication barriers and the value of relational trust; (2) Care Dimension: Competence, Palliative care needs, and Rewarding complexity—highlighting the emotional demands of care, the need for timely palliative integration, and the professional meaning derived from ALS care; (3) Ethical Dimension: Medical interventionism and Patient-centered values—exploring dilemmas around life-sustaining treatments, patient autonomy, and end-of-life decisions. Conclusion: Nurses in ALS care face complex emotional and ethical challenges that call for strong institutional support and palliative training. Enhancing palliative care integration from diagnosis, alongside targeted education and psychological support, is crucial to improving care quality and sustaining the well-being of both patients and nurses.

Background: The progression of Alzheimer’s Disease (AD) deeply affects not only the diagnosed person but also their close relatives, who are often called to take on the role of informal caregivers. This transition is frequently unplanned and emotionally complex, yet poorly understood in its deeper processual dimensions. This study aims to explore and theorize the transition experienced by a family member becoming the primary informal caregiver for a person with advanced AD. Methods: A qualitative study based on the Constructivist Grounded Theory according to Charmaz’s approach (2006) was conducted. In-depth interviews were carried out with 10 participants who had become informal caregivers for a loved one with advanced AD. Data were analyzed using initial coding, focused coding, the constant comparative method, and theoretical coding. Results: Ten caregivers (mean age 39 years, range 35–54; nine females) of patients with advanced AD participated in the study. The analysis revealed a complex, emotionally intense caregiving experience marked by sacrifice, feelings of powerlessness, identity loss, and the necessity of sharing caregiving responsibilities. A core category emerged: A Silent and Certain Willingness to Care, representing the caregivers’ deep, often unconscious commitment to prioritize the care of their loved ones above their own needs. Four interconnected phases characterized the caregiving process: (1) The Changing Daily Life—involving significant sacrifices in personal and social life; (2) Feeling Powerless—confronting the inevitable decline without means to alter the course; (3) Losing Oneself—experiencing physical and psychological exhaustion and a sense of identity loss; and (4) Sharing with Others—seeking external support to sustain caregiving. These findings highlight the evolving nature of becoming a caregiver and the enduring dedication that sustains this role despite the challenges. Conclusions: The progression of AD deeply transforms the lives of caregivers, who become co-sufferers and active participants in the disease’s management. The results underscore the urgency of designing integrative care strategies—including psychological, social, and potentially technological support—that can enhance both patient outcomes and caregiver resilience. Grounded in real-world experiences, this study contributes to the broader neurodegeneration discourse by emphasizing caregiving as a critical factor in long-term disease management and therapeutic success.

Background/Objectives: Childhood overweight and obesity represent a major global public health challenge, with increasing prevalence and significant long-term metabolic, cardiovascular, and psychosocial consequences. Standard pediatric weight-management strategies based on lifestyle modification often achieve modest and variable results, highlighting the need for more personalized and scalable approaches. Artificial intelligence (AI) has emerged as a promising tool to enhance prevention, early risk stratification, and management of pediatric overweight and obesity. Methods: This narrative review was conducted through a structured search of PubMed, Scopus, and Web of Science for English-language studies published up to January 2026. The main search terms included “artificial intelligence”, “machine learning”, and “deep learning”, combined with “child”, “adolescent”, “pediatric”, “childhood obesity”, “pediatric overweight”, “body mass index”, “weight management”, “nutrition”, “diet”, “physical activity”, “lifestyle”, and “behavior change”. After title/abstract and full-text screening according to predefined eligibility criteria, the included studies were qualitatively synthesized and grouped by main application domains. The initial database search identified 412 records. After removal of 96 duplicates, 316 records were screened by title and Full-text assessment was subsequently performed for 175 potentially eligible articles. Following this evaluation, 51 studies met the eligibility criteria and were retained from the database search. Additional relevant articles were identified through manual screening of reference lists and related reviews, resulting in the final set of studies included in the narrative synthesis. Results: The review identified five main domains of AI application in pediatric weight management: risk assessment and prediction, dietary assessment and nutritional support, physical activity and lifestyle monitoring, behavioral and psychological support, and clinical decision support. Across the included literature, AI-based approaches were most frequently applied to predictive modeling using longitudinal BMI or growth trajectories, birth characteristics, parental BMI, sleep duration, physical activity, sedentary behavior, and family or socioeconomic factors. However, the evidence base was largely composed of observational and predictive-modeling studies, whereas interventional studies, real-world implementation studies, and long-term pediatric weight-outcome data remained limited. Conclusions: This narrative review indicates that AI has potential as a complementary tool within multidisciplinary, family-centered pediatric weight-management pathways, particularly for early risk stratification, personalized monitoring, and behavioral support. However, the findings also highlight that current evidence remains mainly exploratory and predictive rather than interventional. Further longitudinal, real-world, and ethically grounded research is required to confirm effectiveness, safety, clinical usefulness, and equitable implementation in pediatric populations.

Aims: To systematically review and synthesize qualitative research exploring the Breast Cancer Survivors (BCSs)’ perception of health promotion interventions and informing strategies to mitigate recurrence risk within five years post-treatment and improve clinical outcomes. Specifically, this study addresses the question: “How do women diagnosed with breast cancer perceive health promotion interventions for recurrence prevention?” Design: A systematic review and qualitative meta-synthesis were performed. Data Sources: A systematic search of scientific databases (CINAHL, MEDLINE, and Scopus) was undertaken in November 2024. The reference list was cross-referenced and hand-searched to identify additional articles. Review Methods: Studies were included if they met the following criteria: they were primary qualitative studies focusing on BCSs within five years post-treatment, involving participants who had completed surgery, radiotherapy, or chemotherapy in the same time frame, as this period is critical for monitoring recurrence and implementing health promotion interventions. Only studies published in peer-reviewed journals and written in Italian, English, French, or Spanish were considered, provided that an abstract and the full text were available. Moreover, eligible studies had to be conducted in high-income or middle-income countries. Studies were excluded if they focused exclusively on advanced or metastatic breast cancer, if they involved mixed cancer populations without reporting separate data for BCSs, or if they were non-qualitative studies or gray literature. The review study protocol was registered in the PROSPERO database (CRD42024626033). Results: The literature search identified 490 records, 13 articles from databases, and 3 articles identified via other methods (web and citation searching) that met inclusion criteria. A narrative synthesis approach allowed the emerging five themes: (I) Challenges, (II) Self-motivation and empowerment, (III) The relationships as a facilitator, (IV) Barriers to change, and (V) Proactive support strategies. Conclusions: Addressing internal and external factors that influence health behaviors is essential to improve adherence, reduce recurrence risk, and enhance quality of life. Tailored interventions, social support, and healthcare engagement are crucial in this effort. Impact: Our meta-synthesis highlighted significant challenges as well as valuable resources for health promotion among BCSs, suggesting practical and tailored approaches to improving the adoption of healthy behaviors, supported by relationships and targeted support strategies.