Ralph Alexander Lloyd-Edwards

Dr. Ralph Alexander Lloyd-Edwards

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Research Focus & Metrics

Academic Career Length

89Years (1938-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 August 2001 in Nature Structural & Molecular Biology
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Journal Article
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TMTrevor F. Moraes
Trevor F. Moraes
RLRalph Alexander Lloyd-Edwards
Ralph Alexander Lloyd-Edwards
SMSean McKenna
Sean McKenna
LPLandon Pastushok
Landon Pastushok
Xiao WeiXiao Wei
Xiao Wei
MEMichael J. Ellison
Michael J. Ellison

16 February 2004 in Journal of Physics: Condensed Matter
Verified
Journal Article
Closed access
PGP A Georgiev
P A Georgiev
DRD K Ross
D K Ross
AMA De Monte
A De Monte
UMU Montaretto-Marullo
U Montaretto-Marullo
RLRalph Alexander Lloyd-Edwards
Ralph Alexander Lloyd-Edwards
DCD Colognesi
D Colognesi

4 June 2019 in Veterinary Radiology & Ultrasound
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RLRalph Alexander Lloyd-Edwards
Ralph Alexander Lloyd-Edwards
HHHanneke Hermans
Hanneke Hermans
SVStefanie Veraa
Stefanie Veraa

1 March 2018 in Acta Veterinaria Scandinavica
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KNKiona Sharon de Nies
Kiona Sharon de Nies
RLRalph Alexander Lloyd-Edwards
Ralph Alexander Lloyd-Edwards
NBNiklas Bergknut
Niklas Bergknut
MBMartijn Beukers
Martijn Beukers
BMBjörn Meij
Björn Meij
Spinal cysts are rare findings in veterinary medicine, but they are increasingly recognized due to the availability of advanced imaging techniques. Extradural meningeal cysts in French Bulldogs have not been reported previously and arachnoid cysts (diverticula) have not been reported at the caudal lumbar (L6–L7) region in dogs. Two French Bulldogs, aged 5 and 8 years, were referred for evaluation of lower back pain and bilateral hind limb neurological deficits. Neurologic examination revealed ataxia and postural deficits in both dogs. Magnetic resonance imaging (MRI) showed cauda equina compression due to a cyst-like lesion at the level of L6–L7 in both cases. The dogs underwent dorsal laminectomy and the meningeal cyst was completely removed in one dog and in the other dog the spinal arachnoid diverticula was marsupialized. In Case 1, histopathology of the cysts was performed and MRI was repeated. Both dogs were pain free during follow-up evaluations. Based on radiological, intra-operative and histopathological findings, the first case was diagnosed as a meningocele connected by a pedicle to the caudal tip of the dural sac forming a dural diverticulum categorized as an extradural spinal cyst type Ib, and Case 2 as a type III intradural arachnoid diverticula. It is concluded that spinal cysts should be included in the differential diagnosis of cauda equina syndrome and lower back pain in French Bulldogs. Results of these cases may be useful for diagnostic and treatment management.

1 April 1996 in Geophysical Journal International
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SBS. K. Buchanan
S. K. Buchanan
RSR. A. Scrutton
R. A. Scrutton
RLRalph Alexander Lloyd-Edwards
Ralph Alexander Lloyd-Edwards
RWR. B. Whitmarsh
R. B. Whitmarsh

9 January 2022 in Animals
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HHHanneke Hermans
Hanneke Hermans
RLRalph Alexander Lloyd-Edwards
Ralph Alexander Lloyd-Edwards
ASAukje J. H. Ferrão-Van Sommeren
Aukje J. H. Ferrão-Van Sommeren
ATAnne A. Tersmette
Anne A. Tersmette
JSJacobine C. M. Schouten
Jacobine C. M. Schouten
Johannes P.A.M. Van LoonJohannes P.A.M. Van Loon
Johannes P.A.M. Van Loon
In standing ophthalmic surgery in horses, a retrobulbar nerve block (RNB) is often placed blindly for anesthesia and akinesia. The ultrasound (US)-guided RNB may have fewer complications, but the two techniques have only been compared once in equine cadavers. This study compares the techniques for success and complication rates and analyzes the effect of training on US guidance. Twenty-two equine cadavers were divided into three groups: blind RNBs were performed bilaterally in eight cadavers, US-guided RNBs were performed bilaterally in seven cadavers, and after US-guided training, blind RNBs were performed bilaterally in seven cadavers. All RNBs were performed by the same two inexperienced operators, and a combination of contrast medium (CM; 1.25 mL) and methylene blue dye (1.25 mL) were injected (2.5 mL total volume). Needle positioning in the periorbita and the distance of the CM to the optic foramen were assessed using computerized tomography (CT). Dye spreading was evaluated by dissection. In group 1, 37.5% of the injections were in the optimal central position in the periorbita; in group 2, 75% and in group 3, 71.4%. There was no significant difference between the groups regarding needle position (groups 1 and 2 p = 0.056; groups 1 and 3 p = 0.069, groups 2 and 3 p = 0.8). The mean CM distribution distance was not significantly different between all groups. Group 1 had 18.75% intraocular injections versus 0% in group 2 and 7.1% in group 3 (not significant). US guidance showed no significant increases in accuracy nor decreases in complications. However, the effects on accuracy showed a trend towards significant improvement, and larger scale follow-up studies might show significant training effects on US guidance.