Premenstrual syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) are characterized by somatic and psychologic symptoms that arise at the luteal phase of the menstrual cycle and subside with menstruation. For definitive diagnosis prospectively self-reported symptoms should demonstrate a cyclic pattern and other psychological pathologies and thyroid dysfunction that may present themselves with similar symptoms should be excluded. Both entities effect millions of women at reproductive age as the prevalence of PMS is given as 10-98% while PMDD effects 2-8%. Sex steroids and neurotransmitters have a huge role in the etiology. The role of vitamins, minerals in etiology and treatment of PMS and PMDD is open to discussion. Drugs that suppress ovarian sex steroid production such as combined oral contraceptives or selective serotonin re-uptake inhibitors (SSRIs) enhancing central serotonin delivery are used for treatment. Life style changes, regular exercise also have a positive effect in mild cases. Tricyclic antidepressants and GnRH analogues can be used in selected cases.
5 October 2024 in American Journal of Reproductive Immunology
Women often face sleep disturbances during key life stages such as adolescence, pregnancy, postpartum period, and perimenopause, influenced by hormonal fluctuations and conditions like polycystic ovary syndrome (PCOS) and premenstrual syndrome (PMS). The goal is to explore women’s sleep disorders as classified in the International Classification of Sleep Disorders-3 (ICSD-3). Through a literature review, this study assesses the management of sleep disorders in women, particularly focusing on the link between gynecological disease and sleep disorders. It scrutinizes landmark research in diagnosing and treating women’s sleep disorders. Observations indicate that physiological changes during adolescence, pregnancy, postpartum, and perimenopause can cause sleep issues, commonly addressed by gynecologists. Conditions like PCOS and PMS are notably linked to increased sleep disorder occurrences. The conclusion underscores the importance of gynecologists’ awareness of the heightened risk of sleep disturbances in women, who often present these issues during consultations.