Prof. Dr. Anna Szakiel
Department of Plant Biochemistry, Institute of Biochemistry, Faculty of Biology, University of Warsaw, 1 Miecznikowa Str., 02-096 Warszawa, Poland
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Academic Career Length
42Years (1985-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications7 April 2010 in Phytochemistry Reviews
Journal Article
26 June 2012 in Phytochemistry Reviews
Journal Article
Anna SzakielCPCezary Pączkowski
Cezary PączkowskiFPFlora Pensec
Flora Pensec
CBChristophe Bertsch
Christophe Bertsch
The health benefits associated with a diet rich in fruit and vegetables include reduction of the risk of chronic diseases such as cardiovascular disease, diabetes and cancer, that are becoming prevalent in the aging human population. Triterpenoids, polycyclic compounds derived from the linear hydrocarbon squalene, are widely distributed in edible and medicinal plants and are an integral part of the human diet. As an important group of phytochemicals that exert numerous biological effects and display various pharmacological activities, triterpenoids are being evaluated for use in new functional foods, drugs, cosmetics and healthcare products. Screening plant material in the search for triterpenoid-rich plant tissues has identified fruit peel and especially fruit cuticular waxes as promising and highly available sources. The chemical composition, abundance and biological activities of triterpenoids occurring in cuticular waxes of some economically important fruits, like apple, grape berry, olive, tomato and others, are described in this review. The need for environmentally valuable and potentially profitable technologies for the recovery, recycling and upgrading of residues from fruit processing is also discussed.
10 July 2020 in Phytochemistry Reviews
Journal Article
ARAgata Rogowska
Agata RogowskaAnna SzakielSterols are integral components of the membrane lipid bilayer and they are involved in many processes occurring in plants, ranging from regulation of growth and development to stress resistance. Maintenance of membrane homeostasis represents one of the principal functions of sterols in plant cells. Plant cell membranes are important sites of perception of environmental abiotic factors, therefore, it can be surmised that sterols may play an important role in the plant stress response. The aim of this review was to discuss the most representative trends in recent studies regarding the role of sterols in plant defense reactions to environmental factors, such as UV radiation, cold and drought stress. Some correlations were observed between changes in the sterol profile, referring to the ratios of individual compounds (including 24-methyl/ethyl sterols and sitosterol/stigmasterol) as well as the relative proportions of conjugated sterols (ASGs, SGs and SEs) and the nature of the stress response. Diversity of sterols and their conjugated forms may allow sessile plants to adapt to environmental stress conditions.
24 July 2014 in Journal of Agricultural and Food Chemistry
Journal Article
FPFlora Pensec
Flora Pensec
CPCezary Pączkowski
Cezary PączkowskiMGMarta Grabarczyk
Marta Grabarczyk
AWAgnieszka Woźniak
Agnieszka Woźniak
MBMélanie Bénard-Gellon
Mélanie Bénard-Gellon
Anna Szakiel +2
20 March 2007 in Protoplasma
Journal Article
MWMałgorzata Wierzbicka
Małgorzata WierzbickaEPE. Przedpełska
E. Przedpełska
RRR. Ruzik
R. Ruzik
LOL. Ouerdane
L. Ouerdane
Katarzyna Monika PawlakAnna Szakiel +2
24 October 2008 in Planta Medica
Journal Article
Anna SzakielDRDariusz Ruszkowski
Dariusz Ruszkowski
AGAnna Grudniak
Anna GrudniakAKAnna Kurek
Anna Kurek
KWKrystyna I. Wolska
Krystyna I. WolskaWJWirginia Janiszowska
Wirginia Janiszowska
+1
The antibacterial and antiparasitic activities of free oleanolic acid and its glucosides and glucuronides isolated from marigold (Calendula officinalis) were investigated. The MIC of oleanolic acid and the effect on bacterial growth were estimated by A600 measurements. Oleanolic acid’s influence on bacterial survival and the ability to induce autolysis were measured by counting the number of cfu. Cell morphology and the presence of endospores were observed under electron and light microscopy, respectively. Oleanolic acid inhibited bacterial growth and survival, influenced cell morphology and enhanced the autolysis of Gram-positive bacteria suggesting that bacterial envelopes are the target of its activity. On the other hand, glycosides of oleanolic acid inhibited the development of L3 Heligmosomoides polygyrus larvae, the infective stage of this intestinal parasitic nematode. In addition, both oleanolic acid and its glycosides reduced the rate of L3 survival during prolonged storage, but only oleanolic acid glucuronides affected nematode infectivity. The presented results suggest that oleanolic acid and its glycosides can be considered as potential therapeutic agents. A600:absorbance at wavelength 600 nm cfu:colony forming unit Gal:galactose Glc:glucose Glcl:3-O-monoglucoside of oleanolic acid GlcOA:other glucosides of oleanolic acid GlcUA:glucuronic acid GlcUAOA:oleanolic acid glucuronides L3:infective larval stage OA:oleanolic acid
About Me
Anna Szakiel – professor of University of Warsaw (Warsaw, Poland), researcher and university lecturer in the Faculty of Biology. Currently the Director of the Institute of Biochemistry and the Head of the Department of Plant Biochemistry. The main professional interests: plant biochemistry and biotechnology, particularly the structure, synthesis, metabolism, distribution, biological and pharmacological activities of natural compounds occurring in medicinal and edible plants. Teaching: General Biochemistry, Biochemistry of Plants, Pharmacognosy, Biochemical Analysis, Plant Metabolic Pathways. Scientific papers, chapters in books and monographs published in the category Plant Science (e.g., in International Journal of Molecular Sciences, Journal of Agricultural and Food Chemistry, Journal of Herbal Medicine, Metabolomics, Molecules, Phytochemistry, Planta Medica, Plant Physiology and Biochemistry, Protoplasma, Steroids). Beneficiary of 15 international scholarships including Socrates-Erasmus program and scholarships funded by French Ministry of Higher Education. Member of Management Committee of COST (European Cooperation in Science and Technology) FA1303 (Food and Agriculture) Action „Sustainable control of grapevine trunk diseases”, 2013-2017. Memberships in Scientific Societies: American Chemical Society, European Federation for the Science and Technology of Lipids, Polish Botanical Society.