Background and Objectives: Anastomotic leakage (AL) is a major complication of colorectal surgery (CRS), increasing morbidity, mortality, and healthcare costs. While several AL risk factors have been identified, the role of aortic calcification (AC) remains unclear. As a marker of systemic atherosclerosis, AC may impair tissue perfusion and anastomotic healing. Additionally, tumor factors (TNM stage, histology, and localization) and patient comorbidities (hypertension, cardiovascular disease, and neoadjuvant therapy) may contribute to AL risk. This study evaluates the association between preoperative AC and AL incidence while considering additional risk factors. Materials and Methods: This retrospective cohort study included 151 patients undergoing CRS from January 2020 to October 2023. Preoperative CT scans classified AC into Stage 0 (none), Stage 1 (50%) of the aortic circumference. Data on demographics, tumor characteristics, neoadjuvant therapy, and comorbidities were collected. AL risk factors were analyzed using univariate and multivariate logistic regression. Results: AL occurred in 5.96% (9/151) of patients. AL incidence was significantly higher in patients with >50% AC (44.47% vs. 11.27%, p = 0.012). Multivariate analysis confirmed AC as an independent AL predictor (OR = 10.38, 95% CI: 1.243–92.118, p = 0.032). Rectal tumor localization (p = 0.038), hypertension (p = 0.027), cardiovascular disease (p = 0.014), and neoadjuvant therapy (p = 0.045) were also associated with increased AL risk. Conclusions: Severe AC is an independent predictor of AL in CRS. Additionally, rectal tumors, hypertension, cardiovascular disease, and neoadjuvant therapy contribute to AL risk. Preoperative vascular assessments and comprehensive risk stratification models may help identify high-risk patients and guide perioperative management strategies to reduce AL incidence.

Aims: Acute diverticulitis (AD) and primary epiploic appendagitis (EA) are two distinct pathological entities that often present with similar clinical features, complicating the process of differential diagnosis. While AD is an inflammatory condition of the diverticula that may progress to significant complications, EA represents a self-limiting inflammatory process originating from ischemic infarction of an epiploic appendage. Accurate differentiation between these two conditions is crucial, as management strategies differ significantly: AD may require hospitalization and antibiotic therapy, while EA is typically managed conservatively. Laboratory parameters have been increasingly investigated to assist in the early and accurate diagnosis of these conditions. This study aims to evaluate the diagnostic value of routine laboratory parameters and to develop a novel scoring system to help clinicians distinguish between AD and EA. Methods: A retrospective analysis was conducted on 184 patients diagnosed with either EA or AD at Hitit University Medical Faculty Erol Olçok Training and Research Hospital between January 1, 2013, and January 1, 2022. Demographic data, laboratory values, including white blood cell count (WBC), neutrophil (NE), lymphocyte (LY), hemoglobin (Hb), platelet (Plt), mean platelet volume (MPV), albumin (Alb), creatine kinase (CK), and C-reactive protein (CRP), lesion localization, comorbidities, hospitalization status, length of stay, complications, interventions, recurrence, and colonoscopy findings were recorded. Comparative analyses between the EA and AD groups were performed. Multivariate analysis identified significant predictors for developing the Ramcho Index (RI) and the Ramcho Score (RS), which integrate laboratory and clinical parameters to create an objective, numeric index and a 0–9 point scale. Results: Among the 184 patients, 109 were diagnosed with AD and 75 with EA. CRP, neutrophil-lymphocyte ratio (NLR), and CRP-albumin ratio (CAR) were significantly elevated in AD (all p

Amaç Papillertiroid kanserinde santral lenf nodlarının metastazının cerrahi öncesi saptanması zordur. Papiller tiroid kanserinin tedavisinde santral lenf nodu diseksiyonunun rolü belirsizliğini koruyor. Bu çalışma, papiller tiroid kanserli hastalarda preoperatif santral lenf nodu metastazı oluşumunu öngörmek için hazır preoperatif klinik özelliklere dayalı bir nomogram oluşturmayı amaçladı Gereç ve Yöntemler 2013-2022 tarihleri arasında bilateral total tiroidektomi yapılmış papillertiroid karsinomu tanılı hastalar tarandı ve 314 hasta çalışmaya dahil edildi. Hastaların demografik verileri, operasyon süresi, TSH, T3, T4 düzeyleri, glukoz/lenfosit oranları (GLR), patoloji raporlarındaki lenfovasküler invazyon, kapsül invazyonu ve boyun metastazı durumu retrospektif olarak taranarak not edildi. Tüm istatistiksel analizler için IBM SPSS 26.0 kullanılarak değerlendirildi. p

Background and Objectives: Anastomotic leakage (AL) is a major complication of colorectal surgery (CRS), increasing morbidity, mortality, and healthcare costs. While several AL risk factors have been identified, the role of aortic calcification (AC) remains unclear. As a marker of systemic atherosclerosis, AC may impair tissue perfusion and anastomotic healing. Additionally, tumor factors (TNM stage, histology, localization) and patient comorbidities (hypertension, cardiovascular disease, neoadjuvant therapy) may contribute to AL risk. This study evaluates the association between preoperative AC and AL incidence while considering additional risk factors. Materials and Methods: This retrospective cohort study included 151 patients undergoing CRS from January 2020 to October 2023. Preoperative CT scans classified AC into Stage 0 (none), Stage 1 (< 50%), and Stage 2 (>50%) of the aortic circumference. Data on demographics, tumor characteristics, neoadjuvant therapy, and comorbidities were collected. AL risk factors were analyzed using univariate and multivariate logistic regression. Results: AL occurred in 5.96% (9/151) of patients. AL incidence was significantly higher in patients with >50% AC (44.47% vs. 11.27%, p=0.012). Multivariate analysis confirmed AC as an independent AL predictor (OR = 10.38, 95% CI: 1.243–92.118, p=0.032). Rectal tumor localization (p=0.038), hypertension (p=0.027), cardiovascular disease (p=0.014), and neoadjuvant therapy (p=0.045) were also associated with increased AL risk. Conclusions: Severe AC is an independent predictor of AL in CRS. Additionally, rectal tumors, hypertension, cardiovascular disease, and neoadjuvant therapy contribute to AL risk. Preoperative vascular assessments and comprehensive risk stratification models may help identify high-risk patients and guide perioperative management strategies to reduce AL incidence.

Introduction: COVID-19 has spread all over the world and caused significant changes in healthcare practices. This is why many expert associations have published new guidelines on COVID-19 management. This study aims to investigate whether the COVID-19 pandemic has an effect on Inguinal hernia (IH) emergencies. Material and Method: A total of 63 patients diagnosed with strangulated/incarcerated inguinal hernia who presented to the emergency surgery department of our hospital between April 2020 and January 2021 during the pandemic (DP) and between April 2019 and January 2020 before the pandemic (BP) were retrospectively analyzed and compared. Results:There was no statistically significant difference between both groups in terms of demographic characteristics. The comparison of the number of admissions, admission time, anesthesia type, hospital stay, postoperative complications, ASA score, hernia, WBC, and CRP averages showed no statistically significant difference between the groups. Moreover, there was no statistically significant difference between the two groups in terms of distributions of hernia types, hernia repair types, mesh use, and additional resection requirement. The comparison of the patients who underwent organ resection by admission time in both groups showed no statistically significant difference. It was observed that the number of patients who required small bowel resection were especially high on the 4th day. In DP, small bowel resection was performed on 4 (66.7%) patients and omentectomy was performed in 2 (33.3%) patients. In BP, only one right hemicolectomy was performed. The comparison of the patients with an admission time of 4th day revealed a statistically significant difference (p=0.03). Conclusion: We observed that morbidity increased as the admission time was delayed. Anticipating that the fear of COVID-19 infection will hold back the emergency response during the pandemic period, patients should be informed not to delay early diagnosis and treatment.

Objective: Gastric cancer surgery, including curative and palliative procedures, is crucial for managing gastric cancer. Accurate assessment of nutritional status is essential for risk stratification and improving patient outcomes. This retrospective study aims to identify the most reliable predictors of postoperative mortality by investigating the correlation between four nutritional scores and the mortality rate following gastric cancer surgery. Material and Method: This retrospective study evaluated 50 patients diagnosed with gastric adenocarcinoma and operated on at Hitit University Department of General Surgery between April 2021 and September 2023. Nutritional scores were calculated using albumin, cholesterol, neutrophil-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio, along with mortality rates. Data collected included age, gender, operation type, laparoscopy usage, albumin, cholesterol, neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, mortality rates, and TNM stages. Nutritional scores were calculated, and their predictive accuracy for mortality was assessed using time-dependent Receiver Operating Characteristic curve analysis. Results: Significant differences in albumin levels, neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and nutritional scores were found between deceased and surviving patients. Specifically, albumin levels were significantly lower in deceased patients (median = 3.5 mg/dL) compared to surviving patients (median = 4.1 mg/ dL, p=0.001). The median neutrophil-to-lymphocyte ratio was higher in deceased patients (p=0.005), and the median lymphocyte-to-monocyte ratio was lower in deceased patients (p=0.009). Among the scores, the Naples Prognostic Score was significantly associated with mortality but was outperformed by the Prognostic Nutritional Index. The Prognostic Nutritional Index had the highest predictive accuracy with an Area Under the curve of 0.792, a sensitivity of 76%, and a specificity of 86.2%, outperforming the others. Conclusion: Among the evaluated scores, the Prognostic Nutritional Index is the most effective predictor of prognosis. Its superior predictive accuracy suggests that the PNI can be utilized to enhance risk assessment and guide nutritional interventions in gastric cancer patients undergoing surgery.