Domantė Lipskytė

Ms. Domantė Lipskytė

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 April 2025 in Medicina
Verified
Journal Article
Open access
PDF file
TVTadas Vanagas
Tadas Vanagas
DLDomantė Lipskytė
Domantė Lipskytė
JTJovita Tamošiūnaitė
Jovita Tamošiūnaitė
KPKestutis Petrikonis
Kestutis Petrikonis
EPEvelina Pajėdienė
Evelina Pajėdienė
Background and Objectives: Sleep disorders are highly prevalent in society and require focused attention within healthcare systems. While patient history, reported complaints, and subjective sleep questionnaires can provide initial insights into potential sleep issues, polysomnography (PSG) remains the gold standard for diagnosing various sleep disorders. However, long waiting times for PSG appointments in many healthcare facilities pose challenges for timely diagnosis and treatment. This study aimed to evaluate the diagnostic value of subjective measures, including patient-reported parameters, in comparison to the objective findings of PSG. Materials and Methods: In this study, we retrospectively analysed the data from 562 patients who underwent clinical evaluation and PSG testing at the Hospital of Lithuanian University of Health Sciences Kaunas Clinics between 2018 and 2024. We report the diagnostic accuracy of different sleep questionnaires to detect various sleep disorders in our population. Results: We report the corresponding sensitivity and specificity values: the Epworth Sleepiness Scale (ESS)—73.2% and 44.1% for detecting severe obstructive sleep apnoea and 87.1% and 76.8% for detecting hypersomnia; the Insomnia Severity Index (ISI)—77.2% and 63.3% for detecting insomnia; the Berlin Questionnaire (BQ)—67.8% and 68.8% for detecting obstructive sleep apnoea; the Ullanlina Narcolepsy Scale (UNS)—84.4% and 58.9% for detecting hypersomnia; the Innsbruck REM Sleep Behaviour Disorder Inventory (RBD-I)—93.3% and 52.5% for detecting RBD; the REM Sleep Behaviour Disorder Single-Question Screen (RBD1Q)—73.3% and 81.0% for detecting RBD; and the Paris Arousal Disorder Severity Scale (PADSS)—57.5% and 90.5% for detecting parasomnia. Conclusions: When comparing our findings with the previous literature, we found that the screening tools generally demonstrated a slightly poorer performance in our population. However, our results suggest that certain individual questions from the comprehensive questionnaires may provide comparable diagnostic values, while reducing the patient burden. We propose a targeted screening approach that integrates fundamental clinical parameters, key screening questions, and selected validated questionnaires, enabling primary care and outpatient clinicians to more efficiently identify patients who may require referral for specialised sleep evaluation and treatment.

31 May 2025 in Medicina
Verified
Journal Article
Open access
PDF file
DLDomantė Lipskytė
Domantė Lipskytė
TVTadas Vanagas
Tadas Vanagas
EPEvelina Pajėdienė
Evelina Pajėdienė
Background and Objectives: According to the literature, Restless Legs Syndrome (RLS) often remains underdiagnosed, with only a small proportion of individuals experiencing symptoms receiving an official diagnosis, highlighting the need for effective screening and diagnostic tools. The International Restless Legs Syndrome Study Group Rating Scale (IRLS) is a widely used tool for assessing the severity of Restless Legs Syndrome (RLS). However, a validated Lithuanian version has not yet been established. This study aimed to validate the Lithuanian version of the IRLS and assess its reliability, diagnostic performance, and correlation with clinical and demographic factors. Materials and Methods: This retrospective study included 136 patients who completed the Lithuanian version of the IRLS and underwent polysomnographic and clinical evaluations at the Department of Neurology of the Lithuanian University of Health Sciences between 2018 and 2024. A total of 134 patients were analyzed: 66 with clinically confirmed RLS and 68 controls without sleep disorders. Statistical analysis included the Mann–Whitney U test, chi-squared tests, Receiver Operating Characteristics (ROC) curve analysis, multivariate logistic regression, and Akaike Information Criterion (AIC). Results: The Lithuanian IRLS demonstrated good diagnostic accuracy with an Area Under the Curve (AUC) value of 0.843 (95% CI: 0.782–0.904), with an optimal cut-off score of 7.50, resulting in high sensitivity (92.4%) and moderate specificity (66.2%). Multivariate regression identified higher IRLS scores (OR = 1.212, 95% CI: 1.084–1.356, p < 0.001) and a higher periodic limb movements of sleep arousal index (PLMSAI) (OR = 1.961, 95% CI: 1.036–3.712, p = 0.039) as significant independent predictors of RLS. After adjustments for age and sex, both IRLS scores and PLMSAI remained statistically significant predictors. Conclusions: the Lithuanian version of IRLS is a valid and reliable instrument for assessing RLS severity. Its diagnostic performance supports its use in clinical and research settings for identifying and monitoring RLS in Lithuanian population.

29 March 2025 in Preprints.org
Verified
Preprint
Open access
PDF file
TVTadas Vanagas
Tadas Vanagas
DLDomantė Lipskytė
Domantė Lipskytė
JTJovita Tamošiūnaitė
Jovita Tamošiūnaitė
KPKestutis Petrikonis
Kestutis Petrikonis
EPEvelina Pajėdienė
Evelina Pajėdienė
Sleep disorders are highly prevalent in society and require focused attention within healthcare systems. While patient history, reported complaints, and subjective sleep questionnaires can provide initial insights into the potential sleep issues, polysomnography (PSG) remains the gold standard for diagnosing various sleep disorders. However, long waiting times for PSG appointments in many healthcare facilities pose challenges for timely diagnosis and treatment. This study aimed to evaluate the diagnostic value of subjective measures, including patient-reported parameters, in comparison to the objective findings of PSG. This study included 562 patients who underwent clinical evaluation and PSG testing at the Hospital of Lithuanian University of Health Sciences Kaunas Clinics between 2018 and 2024. We report diagnostic accuracy of different sleep questionnaires (Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), Berlin Questionnaire (BQ), Ullanlina Narcolepsy Scale (UNS), Innsbruck REM Sleep Behaviour Disorder Inventory (RBD-I), REM Sleep Behaviour Disorder Single-Question Screen (RBD1Q), Paris Arousal Disorders Severity Scale (PADSS)) to detect various sleep disorders in our population. When comparing our findings with previous literature, we found that the screening tools generally demonstrated slightly lower performance in our population. However, our results suggest that certain individual questions from comprehensive questionnaires may provide comparable diagnostic value while reducing patient burden. We propose a targeted screening approach that integrates fundamental clinical parameters, key screening questions, and selected validated questionnaires, enabling primary care and outpatient clinicians to more efficiently identify patients who may require referral for specialized sleep evaluation and treatment.