The recanalization rate and clinical outcome of mechanical thrombectomy for acute ischemic stroke manifesting with basilar artery occlusion are worse for patients with in situ atherosclerotic thrombosis compared with those with embolic origin. BackgroundAcute stroke because of basilar artery occlusion (BAO) represents 1% of all ischemic strokes. However, recanalization rates and treatment outcome for the different pathologic subtypes of BAO stroke are not fully understood.PurposeTo compare the recanalization rate and clinical outcomes of mechanical thrombectomy in different subtypes of BAO.Materials and MethodsEighty-two patients (46 men and 36 women; mean age, 73 years; age range, 20–90 years; mean age in men, 70 years [age range, 20–90 years]; mean age in women, 75 years [age range; 61–90 years]) with acute BAO who underwent mechanical thrombectomy between March 2010 and December 2017 were retrospectively analyzed. Patients were classified into three groups: embolism without vertebral artery (VA) steno-occlusion (group 1), embolism from tandem VA steno-occlusion (group 2), and in situ atherosclerotic thrombosis (group 3). Clinical and angiographic characteristics, recanalization rate, procedure times, and clinical outcomes were compared betwe...

OBJECTIVE: Rete middle cerebral artery (MCA) is extremely rare and has not been frequently discussed. Rete MCA is a weblike anomaly of the MCA that does not coalesce and forms a prominent, large single branch from the plexiform vessels in the fetal stage. The purpose of this study was to further elucidate the clinical and radiological characteristics of patients with rete MCA.METHODS: A total of 2262 cerebral digital subtraction angiography procedures were performed on 1937 patients at the authors’ institution from February 2013 to May 2017. Data analysis included age, sex, clinical symptoms, underlying diseases, coexisting cerebral arterial anomalies, and operative methods and findings.RESULTS: Rete MCAs were found in 13 patients, and the incidence of this anomaly was 0.67% (13 of 1937) in this study. Of the 13 patients, 3 had hemorrhagic strokes, 6 had ischemic strokes, and 4 had no symptoms. Eight patients underwent conservative treatment, and 5 patients underwent surgical treatment. Rete MCA is considered a congenital disease of the cerebral vasculature with the possibility of an acquired abnormality, such as an aneurysm, caused by hemodynamic stress. Although an epidemiological survey of rete MCA was not conducted, it is assumed that rete MCA has a high prevalence in Asia. Ischemic and hemorrhagic stroke events are fairly common in rete MCA.CONCLUSIONS: Clinicians should understand the radiological and clinical features of patients with rete MCA to avoid misdiagnosis and unnecessary treatment. This anomaly should be differentiated from other vascular diseases and patients presenting incidentally should be carefully monitored because of their vulnerability to both hemorrhagic and ischemic strokes.

Jang CK, et al. Brain Tumor Res Treat. 2015 Oct;3(2):103-107. https://doi.org/10.14791/btrt.2015.3.2.103

BACKGROUND AND PURPOSE: Flow-diverter treatment for previously stented aneurysms has been reported to be less effective and prone to complications. In this study, we evaluated the effectiveness and safety of flow diverters for recurrent aneurysms after stent-assisted coiling. MATERIALS AND METHODS: Patients who underwent flow-diverter placement for recurrent aneurysms after stent-assisted coiling between March 2015 and March 2019 were recruited. Clinical and radiographic characteristics and clinical and angiographic outcomes were retrospectively evaluated. RESULTS: Among 133 patients who underwent flow-diverter insertion, 17 (male/female ratio = 5:12; mean age, 53.8 years) were treated for recurrent aneurysms after stent placement with (n = 16) or without (n = 1) coiling. Eight patients initially presented with subarachnoid hemorrhage; 7, with headache; and 2, with visual field defects. Angiographic morphology included large/giant saccular in 12 patients, dissecting in 2, fusiform in 1, traumatic pseudoaneurysm in 1, and ruptured blood blister-like aneurysm in 1. The duration between the first treatment and flow-diverter placement ranged from 2 weeks to 15 months (median, 6 months). Flow-diverter placement was successful in all cases without any complications. All patients had favorable outcomes (mRS, 0–2), without any newly appearing symptoms. Aneurysms were followed up with conventional angiography at least once in 6–18 months. Sixteen aneurysms showed complete occlusion, and 1 aneurysm was enlarged. CONCLUSIONS: Results from this case series investigating flow-diverter placement for recurrent aneurysms after stent-assisted coiling suggested that the procedure is safe and effective. Further study in a larger population may be warranted.

Kim S, et al. J Clin Neurol. 2020 Oct;16(4):624-632. https://doi.org/10.3988/jcn.2020.16.4.624