Basal cell carcinoma (BCC) is considered to be the most common cancer in humans. It has a slow growth rhythm, and for this reason, metastases are rare. For our retrospective study, we selected 180 patients from those who underwent surgery for a variety of skin tumours between January 2019 and August 2022 and whose histopathological examination revealed basal cell carcinoma. All surgeries were performed by plastic surgeons at the “St. John” hospital in Bucharest. The aim of this article is to provide observational data regarding BCC—in terms of histopathology and diagnostic and therapeutic management and to integrate these data into the current knowledge of this pathology.

Background and Objectives: Extensive burns are devastating injuries, especially in children, associating high risk of morbidity and mortality in the absence of immediate and appropriate treatment. Negative-pressure wound therapy (NPWT) has emerged as a versatile tool for the local treatment of burn wounds. This study aims to present our approach in using NPWT for extensive burns in children, emphasizing the indications and outcomes of these very challenging cases, and proposing an algorithm for NPWT use for extensive burn patients, even in low-resource settings. Materials and Methods: We retrospectively analyzed pediatric burn patients admitted between January 2020 and December 2024, selecting the cases with at least 20% TBSA burn and the application of NPWT during treatment, recording indications and parameters of use, treatment period, and results. Results: We identified 12 patients with a burn surface ranging from 20% to 80% TBSA, caused by high-voltage electrical current (6 cases), flame (4 cases), and scalds (2 cases). NWPT was used for 3–25% TBSA for obtaining granulation tissue in very deep burn wounds with bone and tendon exposure, for reducing edema and enhancing spontaneous re-epithelialization in intermediate circumferential burns, and for preparing the wound bed for re-grafting after local infection and graft failure. There were no complications related with the NPWT use and no fatalities. Conclusions: NPWT represents a reliable option for several clinical situations in local burn treatment, for temporary closure of burn areas, graft fixation, burn wound preparation, local infection control, or enhancing re-epithelialization. The proposed algorithm offers a comprehensive overview of indications of NPWT for burn local management and may guide clinical decisions, easing the identification of the best situation and moment to use the device. Our study contributes to the body of knowledge that enforces the evidence of the safe and effective use of NPWT for burn management in the pediatric population.

Background: Labial adhesion in adult women is a rare condition characterized by the complete or partial fusion of the labia minora. According to a 2024 literature review, only 112 cases have been documented over a 38-year period. Methods: We performed a retrospective study, analyzing the files of all patients admitted to the Plastic Surgery Department of “Saint John” Hospital in Bucharest, Romania, over the last 12 years for any cases of labial adhesion. From the medical files, we summarized demographic data, clinical presentation, risk factors, comorbidities, surgical findings, outcomes, follow-up and histopathology results. During the investigated period, we identified three patients admitted to our hospital with labial adhesion with ages between 67 and 79 years. All of them had complete labial fusion with symptomatic complications at the time of diagnosis, and all three required surgery. Tissue samples were collected from all selected patients and sent for histopathological examination, which highlighted several different types of changes. All three cases had a follow-up period of one year. Conclusions: Labial coalescence in adult women is a rare condition more commonly associated with the postmenopausal period. All patients presented with complete labial coalescence, making surgical intervention necessary as topical therapy was not an option. Histopathological examination was crucial to confirm the diagnosis. These results provide important clinical insights and contribute to the limited literature on this rare condition.