ALISON KILLEN

Dr. ALISON KILLEN

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Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 June 2014 in Journal of Happiness Studies
Verified
Journal Article
Closed access
PDF file
AKALISON KILLEN
ALISON KILLEN
AMAnn Macaskill
Ann Macaskill

1 June 2018 in Clinical Neurophysiology
Verified
Journal Article
Open access
MSMyrto Stylianou
Myrto Stylianou
NMNicholas Murphy
Nicholas Murphy
LPLuis Ramon Peraza
Luis Ramon Peraza
SGSara Graziadio
Sara Graziadio
RCRuth Cromarty
Ruth Cromarty
JTJohn-Paul Taylor
John-Paul Taylor
We investigated for quantitative EEG (QEEG) differences between Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) patients and healthy controls, and for QEEG signatures of cognitive fluctuations (CFs) in DLB. We analysed eyes-closed, resting state EEGs from 18 AD, 17 DLB and 17 PDD patients with mild dementia, and 21 age-matched controls. Measures included spectral power, dominant frequency (DF), frequency prevalence (FP), and temporal DF variability (DFV), within defined EEG frequency bands and cortical regions. DLB and PDD patients showed a leftward shift in the power spectrum and DF. AD patients showed greater DFV compared to the other groups. In DLB patients only, greater DFV and EEG slowing were correlated with CFs, measured by the clinician assessment of fluctuations (CAF) scale. The diagnostic accuracy of the QEEG measures was 94% (90.4-97.9%), with 92.26% (80.4-100%) sensitivity and 83.3% (73.6-93%) specificity. Although greater DFV was only shown in the AD group, within the DLB group a positive DFV - CF correlation was found. QEEG measures could classify DLB and AD patients with high sensitivity and specificity. The findings add to an expanding literature suggesting that EEG is a viable diagnostic and symptom biomarker in dementia, particularly DLB.

2 September 2015 in International Psychogeriatrics
Verified
Journal Article
Open access
PDF file
AKALISON KILLEN
ALISON KILLEN
DFDarren Flynn
Darren Flynn
Aoife De BrúnAoife De Brún
Aoife De Brún
NONicola O’bRien
Nicola O’bRien
JOJohn O'Brien
John O'Brien
JTJohn-Paul Taylor
John-Paul Taylor
Background: There is a lack of knowledge regarding the information and support needs of people with dementia with Lewy bodies (DLB) and their families around the time of diagnosis. Methods: A volunteer sample of patients with DLB and their family members completed a web survey hosted by the UK based Lewy Body Society in May 2014. This focused on past experiences of information and support received and what information and support needs would have been beneficial at the time of diagnosis. Results: One hundred and twenty five adults responded to the survey. The majority were first degree relatives or spouses of people with DLB (n = 107, 86%). Approximately 50% (n = 61) reported they had not received any tangible support at diagnosis. Thirteen categories of information needs were identified. Conclusions: People with DLB and their family members are currently inadequately supported at diagnosis. There is a need to address information needs related to symptomology, medication and prognosis, including provision of emotional and instrumental social support. Seeking the views of recipients of information and support is important in ensuring relevance and appropriateness prior to the development of interventions to improve the knowledge and coping skills of people with DLB and caregivers.

3 August 2020 in International Journal of Geriatric Psychiatry
Verified
Journal Article
Open access
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AKALISON KILLEN
ALISON KILLEN
KOKirsty Olsen
Kirsty Olsen
IMIan G. McKeith
Ian G. McKeith
ATAlan J. Thomas
Alan J. Thomas
JOJohn O'Brien
John O'Brien
JTJohn-Paul Taylor
John-Paul Taylor
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25 June 2021 in Dementia
Verified
Journal Article
Open access
PDF file
AKALISON KILLEN
ALISON KILLEN
DFDarren Flynn
Darren Flynn
NONicola O’bRien
Nicola O’bRien
JTJohn-Paul Taylor
John-Paul Taylor
Objectives: Psychosocial support for people with dementia with Lewy bodies (DLB) and family care partners is frequently lacking, despite the need expressed by those with lived experience. Our objective was to examine the feasibility and acceptability of an intervention designed to build coping capability. Design: The design was non-randomised with all participants receiving the intervention. Setting: The setting was a Memory Assessment and Management Service in the Northeast of England. Participants: Participants comprised 19 dyads consisting of a person with DLB and a family care partner. Intervention: The intervention was group-based, with weekly sessions attended for up to four successive weeks. It was informed by Social Cognitive Theory. Measurements: Data were collected on recruitment, attendance and attrition, self-efficacy, mood, stress and participant experience. Results: Recruitment was achieved with minimal attrition and three successive groups were delivered. Care partners felt more in control and able to cope in at least 3 of 13 areas with 73% feeling this way in eight or more areas. Three themes were identified from post-intervention interviews: people like us, outcomes from being a group member and intervention design. Conclusions: A DLB-specific group intervention is acceptable to people with DLB and family care partners, and recruitment is feasible within a specialist service. Participation may enhance understanding of this condition and reduce social isolation. It may improve care partners’ coping capability particularly if targeted towards those with low prior understanding of DLB and more stress. Means of evaluating outcomes for people with DLB need further development.

13 February 2020 in International Journal of Applied Positive Psychology
Verified
Journal Article
Open access
PDF file
AKALISON KILLEN
ALISON KILLEN
AMAnn Macaskill
Ann Macaskill
Life expectancy is increasing globally, which makes understanding what contributes to well-being in older adults crucial for social and economic reasons. This is the first study to categorize positive life events in community dwelling older adults, to explore their fit with psychological well-being models. Volunteers self-defined as well (N = 88), completed diaries identifying three positive events daily for 14 days. Diary entries combated negative stereotypes of ageing by describing older adults with active lives contributing to society. Of nine themes identified through thematic analysis of over 3500 events; seven supported existing well-being models, being activities delivering positive affect and life satisfaction (hedonic model) and demonstrating competence, autonomy, relatedness, self-acceptance, purpose in life, and personal growth (eudemonic models). However, two well-supported new dimensions were also identified within the themes ‘interaction with the physical environment’ and ‘personal well-being’. These new dimensions were labelled ‘life-affirmation and ‘mindfulness’. This suggests the existence of additional considerations related to well-being specifically for older populations, which may indicate a need to broaden the existing models.