Background: Liver Cirrhosis is a growing cause of morbidity and mortality worldwide, but significant knowledge gaps remain regarding disparities in the place of patient death. This study aims to analyze the place of death trends for cirrhosis patients in the United States from 1999 to 2020, to direct preventive and palliative care measures.Methods: In this descriptive study, death certificates were examined using the Centers for Disease Control and Prevention Wide‐Ranging Online Data for Epidemiologic Research (CDC WONDER) database, using ICD codes K70.3, K71.7, and K74. The variables studied were the year, sex, age, race, rural–urban, census regions, and state. Percentages of deaths in each location were trended over time for interpretation.Results: Between 1999 and 2020, a total of 1 090 420 deaths were attributed to cirrhosis. The majority of these fatalities occurred in inpatient medical facilities (48.75%), followed by the decedent's home (25.71%). Men consistently exhibited higher deaths in all settings, especially in medical facility—inpatient settings (31.39%), and the highest deaths were for the 55–64 age group. NH White population reported the highest mortality in all places of death, whereas the South led mortality records among census regions. The least deaths occurred in non‐core (non‐metro) areas, and state‐wise analysis revealed California to have the highest number of deaths (75 723), seconded by Texas (55 447).Conclusion: Mortality due to cirrhosis increased gradually from 1999 to 2019, with a steep rise observed in 2019–2020. Men, the White race, 55–65 years age bracket, and residents of rural and Southern census regions reported the highest number of deaths from cirrhosis.

Background and Aims: Mortality attributed to anaesthetics and therapeutic gases is a public health concern. Recognition of this issue has increased over the years, yet research is limited. This study aimed to explore the trends and geographical differences in the United States. Methods: Deaths attributed to toxicity, adverse effects, and underdosing of anaesthetics were traced from 1999 to 2022 using the data available on the Centers for Disease Control and Prevention’s Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) website. The data were analysed according to gender, age, race, and geographic region. Results: Between 1999 and 2022, there were 10,157 anaesthesia-related deaths. The age-adjusted mortality rate (AAMR) increased from 0.1 to 0.4 from 1999 to 2022. AAMR stayed the same from 1999 to 2014, that is, 0.1 [annual percent change (APC) -0.12; 95% confidence interval (CI): -3.9 to 3.4] and increased from 2014 to 2020 to 0.4 (APC: 27.28; 95% CI: 20.8 to 49.4) and from 2020 to 2022 at 0.42 (APC: 3.54; 95% CI: -4.6 to 17.1). Among Hispanics/Latinos, mortality decreased before having a sharp increase after 2019 (AAMR 0.09, 95% CI: 0.07–0.13). Non-Hispanics (NHs) showed a similar pattern, with a notable increase seen after 2016 (Overall AAMR 0.14, 95% CI: 0.13–0.16). The northeast region exhibited an AAMR of 0.21 (0.18–0.25), 95% CI. Conclusion: Following a period of decline, mortality has increased in the United States since 2014. AAMRs were high among males, NHs, and residents of the Northeast region. The study highlights the increasing mortality along with the presence of disparities among gender, race, and region.