Paata Pruidze

Dr. Paata Pruidze

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Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 November 2023 in Journal of Anatomy
Verified
Journal Article
Open access
JWJeremias T. Weninger
Jeremias T. Weninger
PPPaata Pruidze
Paata Pruidze
GDGiorgi Didava
Giorgi Didava
TRTobias Rossmann
Tobias Rossmann
SGStefan Geyer
Stefan Geyer
WWWolfgang J. Weninger
Wolfgang J. Weninger
Connective or muscular tissue crossing the axilla is named axillary arch (of Langer). It is known to complicate axillary surgery and to compress nerves and vessels transiting from the axilla to the arm. Our study aims at systematically researching the frequency, insertions, tissue composition and dimension of axillary arches in a large cohort of individuals with regard to gender and bilaterality. In addition, it aims at evaluating the ability of axillary arches to cause compression of the axillary neurovascular bundle. Four hundred axillae from 200 unembalmed and previously unharmed cadavers were investigated by careful anatomical dissection. Identified axillary arches were examined for tissue composition and insertion. Length, width and thickness were measured. The relation of the axillary arch and the neurovascular axillary bundle was recorded after passive arm movements. Twenty‐seven axillae of 18 cadavers featured axillary arches. Macroscopically, 15 solely comprised muscular tissue, six connective tissue and six both. Their average length was 79.56 mm, width 7.44 mm and thickness 2.30 mm. One to three distinct insertions were observed. After passive abduction and external rotation of the arm, 17 arches (63%) touched the neurovascular axillary bundle. According to our results, 9% of the Central European population feature an axillary arch. Approximately 50% of it bilaterally. A total of 40.74% of the arches have a thickness of 3 mm or more and 63% bear the potential of touching or compressing the neuromuscular axillary bundle upon arm movement.

13 July 2021 in Clinical Anatomy
Verified
Journal Article
Open access
PDF file
PPPaata Pruidze
Paata Pruidze
PMPlamena Mincheva
Plamena Mincheva
JWJeremias T. Weninger
Jeremias T. Weninger
LRLukas Reissig
Lukas Reissig
AHAndreas Hainfellner
Andreas Hainfellner
WWWolfgang J. Weninger
Wolfgang J. Weninger
Nasopharyngeal swabs are performed to collect material for diagnosing diseases affecting the respiratory system, such as Covid‐19. Yet, no systematic anatomical study defines concrete prerequisites for successfully targeting the nasopharyngeal mucosa. We therefore aim at simulating nasopharyngeal swabs in human body donors to characterize parameters allowing and supporting to enter the nasopharynx with a swab, while avoiding endangering the cribriform plate. With the aid of metal probes and commercial swabs a total of 314 nasopharyngeal swabs in anatomical head/neck specimens stemming from 157 body donors were simulated. Important anatomical parameters were photo‐documented and measured. We provide information on angles and distances between prominent anatomical landmarks and particularly important positions the probe occupies during its advancement through the nares to the upper and lower parts of the nasopharynx and cribriform plate. Based on these data we suggest a simple and safe three‐step procedure for conducting nasopharyngeal swabs. In addition, we define easily recognizable signals for its correct performance. Evaluations prove that this procedure in all specimens without deformations of the nasal cavity allows the swab to enter the nasopharynx, whereas a widespread used alternative only succeeds in less than 50%. Our data will be the key for the successful collection of nasopharyngeal material for detecting and characterizing pathogens, such as SARS‐CoV‐2, which have a high affinity to pharyngeal mucosa. They demonstrate that the danger for damaging the cribriform plate or olfactory mucosa with swabs is unlikely, but potentially higher when performing nasal swabs.

10 November 2023 in Journal of Plastic, Reconstructive & Aesthetic Surgery
Verified
Journal Article
Open access
VKVilliam Vejbrink Kildal
Villiam Vejbrink Kildal
SMStefan Meng
Stefan Meng
PPPaata Pruidze
Paata Pruidze
LRLukas Reissig
Lukas Reissig
WWWolfgang J. Weninger
Wolfgang J. Weninger
ARAndrés Rodriguez-Lorenzo
Andrés Rodriguez-Lorenzo
Myectomies of the lower lip depressor muscles have unexplained high failure rates. This study aimed to examine the depressor anguli oris (DAO) muscle using high-resolution ultrasound to identify potential anatomical explanations for surgical failures and to determine the accuracy of utilizing preoperative ultrasound assessment to improve myectomies. Anatomical features of DAO and the surrounding anatomy were examined in 38 hemifaces of human body donors using high-resolution ultrasound and dissection. The ultrasound and dissection measurements showed the DAO muscle width to be 16.2 ± 2.9 versus 14.5 ± 2.5 mm, respectively, and the location of the lateral muscle border 54.4 ± 5.7 versus 52.3 ± 5.4 mm lateral to the midline. In 60% of the cases, the facial artery was either completely covered by lateral DAO muscle fibers or was found to be in direct contact with the lateral border. Significant muscle fiber continuity was present between the DAO and surrounding muscles in 5% of cases, whereas continuity between the depressor labii inferioris and surrounding muscles was considerably more common and pronounced. High-resolution ultrasound can accurately reveal important preoperative anatomical information in myectomies. Two potential explanations for the surgical failures were discovered: an overlap of lateral DAO muscle fibers over the facial artery could lead to inadequate resections and continuity with the surrounding muscles might lead to muscle function takeover despite adequate resections. Both can be uncovered preoperatively by the surgeon through a brief, directed ultrasound examination, which may allow for modification of the surgical plan to reduce surgical failure.

7 January 2023 in Ultrasound in Medicine & Biology
Verified
Journal Article
Closed access
PPPaata Pruidze
Paata Pruidze
TRTobias Rossmann
Tobias Rossmann
JWJeremias T. Weninger
Jeremias T. Weninger
GDGiorgi Didava
Giorgi Didava
AMAtieh Seyedian Moghaddam
Atieh Seyedian Moghaddam
SMStefan Meng
Stefan Meng

6 January 2026 in European Journal of Cardio-Thoracic Surgery
Verified
Journal Article
Open access
EOEmilio Osorio-Jaramillo
Emilio Osorio-Jaramillo
JEJasmine El-Nashar
Jasmine El-Nashar
SKSatoshi Kainuma
Satoshi Kainuma
EUEwald Unger
Ewald Unger
WSWilhelm Schreiner
Wilhelm Schreiner
MEMarek P Ehrlich
Marek P Ehrlich
Objectives: To evaluate a novel aortic anastomotic device designed for end-to-end anastomosis between a vascular prosthesis and the native aorta, aiming to facilitate aortic replacement and shorten circulatory arrest times. Methods: Ascending aortic replacements with Dacron grafts and external Teflon felt strips were performed in 10 fresh human cadavers. Five procedures were performed using a continuous 4-0 polypropylene running suture, and 5 with the aortic anastomotic device. The device deploys single straight needle pins through the aortic wall and felt, securing them externally with a cap. Explanted graft-aorta specimens were connected to a pressure pump filled with glycerol/H2O solution (170/90 mm Hg, 5 minutes). The primary end-point was anastomotic time; secondary end-points were fluid loss and tissue trauma assessed macroscopically and microscopically. Results: Median time for end-to-end anastomosis was significantly shorter with the aortic anastomotic device (05:39 [interquartile range, IQR 04:22-06:30] minutes:seconds) compared to conventional suture (09:17 [IQR 06:53-10:34]; P = .016). The number of pins per anastomosis was lower than the number of stitches (17 [15-18] vs 22 [21-24]; P = .008). Fluid loss was comparable between groups (100 [52.5-174.5] mL vs 45 [21.8-104.0] mL; P = .310). Microscopy revealed intimal tears in all sutured specimens but in none of the device group, P = .008. Conclusions: In this preliminary human cadaver study, the novel aortic anastomotic device proved to be technically feasible, significantly faster than conventional suturing, and produced less tissue trauma while maintaining comparable sealing. The device may shorten circulatory arrest times and improve anastomotic quality in aortic surgery. Further in vivo studies are warranted. Clinical trial registration: This was a prospective experimental cadaver study, not eligible for registration in a public registry for clinical trials.

3 December 2024 in Frontiers in Cardiovascular Medicine
Verified
Journal Article
Open access
PDF file
PPPaata Pruidze
Paata Pruidze
JWJeremias T. Weninger
Jeremias T. Weninger
GDGiorgi Didava
Giorgi Didava
KSKaroline M. Schwendt
Karoline M. Schwendt
SGStefan H. Geyer
Stefan H. Geyer
WWWolfgang J. Weninger
Wolfgang J. Weninger
Objective: Spinal cord ischemia due to damage or occlusion of the orifices of aortic segmental arteries (ASA) is a serious complication of open and endovascular aortic repair. Our study aims to provide detailed descriptions of the proximal course of the ASAs and metric information on their origins.Materials and methods: Initially, 200 randomly selected, embalmed cadavers of human body donors were anatomically dissected and systematically examined. On macroscopic inspection, 47 showed severe pathologies and were excluded. Of the remaining 153, 73 were males and 80 females.Results: In total, 69.9% of the aortae showed 26–28 ASA orifices. In 59.5% the most proximal ASA, at least unilaterally, was the third posterior intercostal artery, which originated from the descending aorta at approximately 10% of its length. In 56.2%, the left and right ASAs had a common origin in at least one body segment. This mainly affected the abdominal aorta and L4 in particular (54.2%). The ASAs of lumber segments 1–3 originated strictly segmentally. In contrast, in 80.4%, at least one posterior intercostal artery originated from a cranially or caudally located ipsilateral ASA. Such an arrangement was seen along the entire thoracic aorta. Further descriptions of variants and metric data on ASA orifices are presented.Conclusion: Our large-scale study presents a detailed topographic map of ASAs. It underscores the value of preoperative CT councils and provides crucial information for interpreting the results. Furthermore, it aids in planning and conducting safe aortic intervention and assists in deciding on single- or two-staged stent graft procedures.