Optimizing the wind environment within university dormitory areas is essential for ensuring student safety, enhancing living comfort, and improving building energy efficiency. In this study, the wind environment of multi-story university dormitories in cold regions is comprehensively investigated through computational fluid dynamics (CFD) simulations conducted with the PHONECIS software (version 2019), combined with orthogonal experimental design methods for systematic analysis and optimization. Through orthogonal experimental design, the effects of key morphological parameters—including building layout, length, width, and height—on the near-ground wind environment were evaluated. Among these, building width exerted the greatest influence, followed by building length, layout form, and finally building height. Based on the analysis, the optimal design scheme features a staggered building layout, with individual dormitory buildings measuring 60 m in length, 16 m in width, and 11.4 m in height. This optimized design was implemented in the multi-story dormitory area of the eastern section of Chang’an University’s New Campus. A comparative analysis of wind speed distribution before and after optimization, conducted specifically for the outdoor spaces during the winter season, revealed that the average near-ground wind speed was reduced from 3.3 m/s to 2.7 m/s, achieving an 18% reduction. The staggered arrangement and adjusted building proportions effectively dispersed airflow, mitigated high-velocity zones, and significantly enhanced outdoor wind comfort and pedestrian safety. This study introduces a morphology–wind environment coupling strategy from an architectural perspective to guide the design of dormitory buildings in cold regions. Rather than focusing on mathematical modeling, the research emphasizes design-oriented outcomes aimed at informing and optimizing practical architectural solutions for safer, more comfortable, and energy-efficient campus living environments.