A new hydrosoluble triazatruxene derivative (AZATRUX) is reported to selectively bind to G-quadruplex DNA, as derived by ESI-MS measurements and competition experiments.

In this review article, the phytochemistry of the species belonging to the Araucariaceae family is explored. Among these, in particular, it is given a wide overview on the phytochemical profile of Wollemia genus, for the first time. In addition to this, the ethnopharmacology and the general biological activities associated to the Araucariaceae species are singularly described. Lastly, the chemotaxonomy at the genus and family levels is described and detailed.