Cynthia L. Green

Dr. Cynthia L. Green


Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 November 2019 in Journal of Bone and Joint Surgery
Verified
Journal Article
Open access
JBJanet Prvu Bettger
Janet Prvu Bettger
CGCynthia L. Green
Cynthia L. Green
DHDaJuanicia N. Holmes
DaJuanicia N. Holmes
ACAnang Chokshi
Anang Chokshi
RMRichard C. Mather
Richard C. Mather
EPEric D. Peterson
Eric D. Peterson
Background: Financial burden for patients, providers, and payers can reduce access to physical therapy (PT) after total knee arthroplasty (TKA). The purpose of the present study was to examine the effect of a virtual PT program on health-care costs and clinical outcomes as compared with traditional care after TKA. Methods: At least 10 days before unilateral TKA, patients from 4 clinical sites were enrolled and randomized 1:1 to the virtual PT program (involving an avatar [digitally simulated] coach, in-home 3-dimensional biometrics, and telerehabilitation with remote clinician oversight by a physical therapist) or to traditional PT care in the home or outpatient clinic. The primary outcome was total health-care costs for the 12-week post-hospital period. Secondary (noninferiority) outcomes included 6 and 12-week Knee injury and Osteoarthritis Outcome Score (KOOS); 6-week knee extension, knee flexion, and gait speed; and 12-week safety measures (patient-reported falls, pain, and hospital readmissions). All outcomes were analyzed on a modified intent-to-treat basis. Results: Of 306 patients (mean age, 65 years; 62.5% women) who were randomized from November 2016 to November 2017, 290 had TKA and 287 (including 143 in the virtual PT group and 144 in the usual care group) completed the trial. Virtual PT had lower costs at 12 weeks after discharge than usual care (median, $1,050 compared with $2,805; p < 0.001). Mean costs were $2,745 lower for virtual PT patients. Virtual PT patients had fewer rehospitalizations than the usual care group (12 compared with 30; p = 0.007). Virtual PT was noninferior to usual PT in terms of the KOOS at 6 weeks (difference, 0.77; 90% confidence interval [CI], −1.68 to 3.23) and 12 weeks (difference, −2.33; 90% CI, −4.98 to 0.31). Virtual PT was also noninferior to usual care at 6 weeks in terms of knee extension, knee flexion, and gait speed and at 12 weeks in terms of pain and hospital readmissions. Falls were reported by 19.4% of virtual PT patients and 14.6% of usual care patients (difference, 4.83%; 90% CI, −2.60 to 12.25). Conclusions: Relative to traditional home or clinic PT, virtual PT with telerehabilitation for skilled clinical oversight significantly lowered 3-month health-care costs after TKA while providing similar effectiveness. These findings have important implications for patients, health systems, and payers. Virtual PT with clinical oversight should be considered for patients managed with TKA. Level of Evidence: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.

27 April 2018 in BMC Cancer
Verified
Journal Article
Open access
PDF file
ALAlexander Lazarides
Alexander Lazarides
Julia VisgaussJulia Visgauss
Julia Visgauss
DNDaniel P. Nussbaum
Daniel P. Nussbaum
CGCynthia L. Green
Cynthia L. Green
DBDan G. Blazer
Dan G. Blazer
WEWilliam C. Eward
William C. Eward
In the United States, race and socioeconomic status are well known predictors of adverse outcomes in several different cancers. Existing evidence suggests that race and socioeconomic status may impact survival in soft tissue sarcoma (STS). We investigated the National Cancer Database (NCDB), which contains several socioeconomic and medical variables and contains the largest sarcoma patient registry to date. Our goal was to determine the impact of race, ethnicity and socioeconomic status on patient survival in patients with soft tissue sarcoma of the extremities (STS-E). We retrospectively analyzed 14,067 STS-E patients in the NCDB from 1998 through 2012. Patients were stratified based on race, ethnicity and socioeconomic status. Univariate and multivariate analyses were used to correlate specific outcomes and survival measures with these factors. Then, long-term survival between groups was evaluated using the Kaplan-Meier (KM) method with comparisons based on the log-rank test. Multiple variables were analyzed between two groups. Of the 14,067 patients analyzed, 84.9% were white, 11% were black and 4.1% were Asian. Black patients were significantly more likely (7.18% vs 5.65% vs 4.47%) than white or Asian patients to receive amputation (p = 0.027). Black patients were also less likely to have either an above-median education level or an above-median income level (p < 0.001). In addition, black patients were more likely to be uninsured (p < 0.001) and more likely to have a higher Charleson Comorbidity Score than white or Asian patients. Tumors were larger in size upon presentation in black patients than in white or Asian patients (p < 0.001). Black patients had significantly poorer overall survival than did white or Asian patients (p < 0.001) with a KM 5-year survival of 61.4% vs 66.9% and 69.9% respectively, and a 24% higher independent likelihood of dying in a multivariate analysis. This large database review reveals concerning trends in black patients with STS-E. These include larger tumors, poorer resources, a greater likelihood of amputation, and poorer survival than white and Asian patients. Future studies are warranted to help ensure adequate access to effective treatment for all patients.

1 February 2022 in Journal of Shoulder and Elbow Surgery
Verified
Journal Article
Closed access
DGDaniel E. Goltz
Daniel E. Goltz
RBRobert A. Burnett
Robert A. Burnett
JLJay M. Levin
Jay M. Levin
JWJohn R. Wickman
John R. Wickman
EBElshaday S. Belay
Elshaday S. Belay
CKChristopher S. Klifto
Christopher S. Klifto

1 March 1997 in International Journal of Geriatric Psychiatry
Verified
Journal Article
Closed access
PDF file
BLBrian Lawlor
Brian Lawlor
PAPaul S. Aisen
Paul S. Aisen
CGCynthia L. Green
Cynthia L. Green
EFElizabeth Fine
Elizabeth Fine
JSJames Schmeidler
James Schmeidler

23 March 2023 in Environmental Research
Verified
Journal Article
Closed access
VRVictor L. Roggl
Victor L. Roggl
CGCynthia L. Green
Cynthia L. Green
BLBeiyu Liu
Beiyu Liu
JCJohn M. Carney
John M. Carney
CGCarolyn H. Glass
Carolyn H. Glass
EPElizabeth N. Pavlisko
Elizabeth N. Pavlisko

1 February 2004 in JACC
Verified
Journal Article
Closed access
MRMatthew T Roe
Matthew T Roe
CGCynthia L. Green
Cynthia L. Green
RGRobert P Giugliano
Robert P Giugliano
C Michael GibsonC Michael Gibson
C Michael Gibson
KBKenneth Baran
Kenneth Baran
MKMitchell W Krucoff
Mitchell W Krucoff