Nathaniel P. Mercer

Dr. Nathaniel P. Mercer

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 October 2023 in Foot & Ankle Orthopaedics
Verified
Journal Article
Open access
MAMohammad T. Azam
Mohammad T. Azam
JBJames J. Butler
James J. Butler
MWMatthew B. Weiss
Matthew B. Weiss
HUHugo A. Ubillus
Hugo A. Ubillus
NKNoah Kirschner
Noah Kirschner
JKJohn G. Kennedy
John G. Kennedy
Background: As no evidence-based treatment guidelines exist for chronic Achilles tendon rupture (CATR), a systematic review of the literature was performed to compare the different treatment options and recommend a literature-based algorithm. Methods: In June 2022, MEDLINE, Embase, and Cochrane Library databases were systematically reviewed based on the PRISMA guidelines. The level of evidence (LOE) and quality of evidence were evaluated, and statistics on clinical outcomes and complications were calculated. Results: Twenty-seven studies with 614 patients were included. Three studies were LOE III and 25 studies were LOE IV. The mean Achilles tendon rupture score improved from a preoperative weighted mean of 38.8 ± 12.4 to a postoperative score 90.6 ± 4.7. The overall complication rate was 11.4%. Single techniques were used in 23 studies and dual techniques were used in 5 studies. The FHL tendon transfer was the most frequently used technique. We devised an algorithmic approach based on time from injury to surgical intervention and the length of the gap between the tendon stumps: >3 months: FHL transfer; <3 months (a) gap 5 cm, semitendinosus autograft. Conclusion: Surgical management of CATR produced improvements in patient-reported outcome scores at midterm follow up, but a high complication rate (11.4%) was noted. Our proposed treatment algorithm may assist in shared decision making for this complex problem.

5 January 2022 in Foot & Ankle International
Verified
Journal Article
Closed access
PDF file
JDJari Dahmen
Jari Dahmen
SBSteve Bayer
Steve Bayer
JTJames Toale
James Toale
CMConor Mulvin
Conor Mulvin
EHEoghan T. Hurley
Eoghan T. Hurley
CMChristopher D. Murawski
Christopher D. Murawski
Background: An international consensus group of experts was convened to collaboratively advance toward consensus opinions based on the best available evidence on key topics within cartilage repair of the ankle. The purpose of this article is to present the consensus statements on osteochondral lesions of the tibial plafond (OLTP) and on ankle instability with ankle cartilage lesions developed at the 2019 International Consensus Meeting on Cartilage Repair of the Ankle. Methods: Forty-three experts in cartilage repair of the ankle were convened and participated in a process based on the Delphi method of achieving consensus. Questions and statements were drafted within 4 working groups focusing on specific topics within cartilage repair of the ankle, after which a comprehensive literature review was performed and the available evidence for each statement was graded. Discussion and debate occurred in cases where statements were not agreed on in unanimous fashion within the working groups. A final vote was then held. Results: A total of 11 statements on OLTP reached consensus. Four achieved unanimous support and 7 reached strong consensus (greater than 75% agreement). A total of 8 statements on ankle instability with ankle cartilage lesions reached consensus during the 2019 International Consensus Meeting on Cartilage Repair of the Ankle. One achieved unanimous support, and seven reached strong consensus (greater than 75% agreement). Conclusion: These consensus statements may assist clinicians in the management of these difficult clinical pathologies. Level of Evidence: Level V, mechanism-based reasoning.


17 March 2025 in Journal of Bone and Joint Surgery
Verified
Journal Article
Closed access
KNKian Niknam
Kian Niknam
BLBradley A Lezak
Bradley A Lezak
NMNathaniel P. Mercer
Nathaniel P. Mercer
JRJoseph X. Robin
Joseph X. Robin
EHErik Hansen
Erik Hansen
RSRan Schwarzkopf
Ran Schwarzkopf
Background: Arthrofibrosis is a debilitating complication of total knee arthroplasty (TKA) and may benefit from arthroscopic lysis of adhesions (LOA) to improve range of motion and decrease pain. However, the rates of periprosthetic joint infection (PJI) and of the need for future revision TKA (rTKA) have only been studied in a limited capacity in the literature. In this study, we aimed to compare PJI and revision outcomes in patients who had undergone TKA between those who subsequently underwent arthroscopic LOA and those who did not undergo arthroscopic LOA. Methods: The PearlDiver database was utilized to identify patients who had undergone primary TKA between 2016 and 2021. ICD-10 (International Classification of Diseases, Tenth Revision) and CPT (Current Procedural Terminology) codes were then used to identify patients who underwent LOA for arthrofibrosis. The rates of PJI and rTKA were compared between patients who did and did not undergo LOA. Multivariable logistic and Cox regressions, controlling for age, sex, Charlson Comorbidity Index, tobacco use, and a body mass index of >30 kg/m2, were performed to compare the rates of PJI and revision between the LOA and no-LOA groups. Results: A total of 383,143 patients were identified, of whom 703 had undergone arthroscopic LOA. Patients who underwent LOA had higher overall rates of PJI (2.7% versus 1.3%; p = 0.001) and all-cause revision (9.8% versus 1.8%; p < 0.001) than those who did not. Patients who underwent LOA had significantly higher odds of PJI (odds ratio [OR], 2.00; p < 0.014), aseptic loosening-related revision (OR, 3.31; p = 0.002), and all-cause revision (OR, 5.32; p < 0.001) within 1 year after the initial TKA. There was no significant difference in 1-year PJI-related revisions between the groups (OR, 1.71; p = 0.193). In a time-to-event analysis, patients undergoing LOA had significantly higher risks of PJI (p = 0.003) and all-cause revision (p = 0.001) but not PJI-related revision (p = 0.322) or aseptic loosening-related revision (p = 0.111). Conclusions: Arthroscopic LOA after primary TKA was associated with higher rates of PJI and subsequent revision surgery. Surgeons should consider the results of these studies when counseling patients on the importance of early rehabilitation and improving modifiable risk factors after TKA. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

1 June 2021 in Journal of Cartilage & Joint Preservation
Verified
Journal Article
Open access
YSYoshiharu Shimozono
Yoshiharu Shimozono
JDJohn F. Dankert
John F. Dankert
TDTimothy W. Deyer
Timothy W. Deyer
NMNathaniel P. Mercer
Nathaniel P. Mercer
JKJohn G. Kennedy
John G. Kennedy

5 January 2025 in Foot and Ankle Surgery
Verified
Journal Article
Closed access
NMNathaniel P. Mercer
Nathaniel P. Mercer
BLBradley A Lezak
Bradley A Lezak
DHDavis Hedbany
Davis Hedbany
JBJames J. Butler
James J. Butler
SKSebastian Krebsbach
Sebastian Krebsbach
JKJohn G. Kennedy
John G. Kennedy