Improvement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and Symmetry

Protein Knockdown Using Methyl Bestatin−Ligand Hybrid Molecules: Design and Synthesis of Inducers of Ubiquitination-Mediated Degradation of Cellular Retinoic Acid-Binding Proteins

Design, synthesis and biological evaluation of nuclear receptor-degradation inducers

Discovery of Small Molecules that Induce the Degradation of Huntingtin

Proximity Histidine Labeling by Umpolung Strategy Using Singlet Oxygen

Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein