Ekmel Burak Ozsenel

Dr. Ekmel Burak Ozsenel

orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 February 2015 in The International Journal of Cardiovascular Imaging
Verified
Journal Article
Closed access
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MSMurat Sunbul
Murat Sunbul
MBMehmet Bozbay
Mehmet Bozbay
CMCeyhun Mammadov
Ceyhun Mammadov
ACAltug Cincin
Altug Cincin
HAHalil Atas
Halil Atas
YBYelda Basaran
Yelda Basaran

25 October 2025 in Medicina
Verified
Journal Article
Open access
PDF file
NBNermin Mutlu Bilgiç
Nermin Mutlu Bilgiç
GKGüldan Kahveci
Güldan Kahveci
HAHüseyin Aykut
Hüseyin Aykut
YÖYasemin özer
Yasemin özer
EOEkmel Burak Ozsenel
Ekmel Burak Ozsenel
SBSema Basat
Sema Basat
Background and Objectives: Percutaneous endoscopic gastrostomy (PEG) is a widely accepted method for long-term enteral nutrition, but procedure-related complications and early mortality remain major concerns. Nutritional and inflammatory indices such as serum albumin, C-reactive protein (CRP), Prognostic Nutritional Index (PNI), and Nutrition Risk Screening (NRS-2002) may provide prognostic value, yet comparative data in PEG cohorts are limited. This study aimed to identify predictors of complications and 90-day mortality after PEG and to compare the prognostic performance of nutritional indices. Materials and Methods: A retrospective cohort of 122 consecutive adult patients undergoing PEG between January and December 2024 was analyzed. Demographic, clinical, and laboratory parameters were collected, including albumin, CRP, PNI, and NRS-2002. Complications were categorized as early (≤30 days) or late (>30 days), and all-cause mortality was assessed at 30 and 90 days. Univariate and multivariate logistic regression models were used to evaluate predictors of complications and 90-day mortality. To address multicollinearity, albumin, PNI, and NRS-2002 were separately tested in adjusted models, with model performance assessed by AIC, BIC, Nagelkerke R2, and C-index. Results: Early complications occurred in 4.9% and late complications in 8.2% of patients, for a total complication rate of 13.1%. Thirty-day mortality was 4.1%, 90-day mortality 17.2%, and total in-hospital mortality during the study year 30.3%. Neuromuscular indication was independently associated with increased risk of complications (aOR 5.0, 95% CI 1.2–20.0, p = 0.028) but reduced 90-day mortality (aOR 0.15, 95% CI 0.03–0.80, p = 0.025). Lower baseline albumin independently predicted higher 90-day mortality (aOR 0.92, 95% CI 0.86–0.99, p = 0.034). Elevated CRP demonstrated a borderline association with mortality (p = 0.051), while NRS-2002 ≥5 and Δ-PNI showed borderline trends toward increased mortality risk. In model comparison, none of the nutritional indices achieved independent statistical significance, but all demonstrated similar performance (AIC = 114, C-index 0.72–0.74). Conclusions: PEG outcomes are strongly influenced by baseline indication and nutritional–inflammatory status. Neuromuscular patients and patients with dysphagia face higher complication risk but lower short-term mortality, while hypoalbuminemia, elevated CRP, and high NRS-2002 or declining PNI identify patients at greater risk of death. Systematic integration of albumin, CRP, PNI, and NRS-2002 may improve risk stratification and management in PEG candidates.

Verified
Journal Article
Open access
PDF file
EOEkmel Burak Ozsenel
Ekmel Burak Ozsenel
GKGüldan Kahveci
Güldan Kahveci
YPYıldız Pekcioğlu
Yıldız Pekcioğlu
BGBEYTULLAH GÜNER
BEYTULLAH GÜNER
SBSema Basat
Sema Basat
Background: Malnutrition is increasingly prevalent due to rising life expectancy, oncological cases, and chronic diseases. Early detection is crucial for rehabilitation, complication prevention, and cost reduction. However, nutritional support is often suboptimal. This study aimed to determine malnutrition prevalence and nutritional support status within our hospital. Methods: A point prevalence study was conducted in adult inpatient clinics (excluding pediatrics, infectious diseases, and intensive care) by a 12-member team following ethical approval. NRS-2002 scores, arm/calf circumferences, BMI, and laboratory data (albumin, leukocytes, lymphocytes, neutrophils, hemoglobin, CRP, creatinine) were assessed. Enteral and parenteral nutrition treatments were recorded. Patients with NRS-2002 scores ≥ 3 were classified as at risk of malnutrition. Results: Among 178 patients, 24.7% were at risk of malnutrition. Surgical clinics had a higher malnutrition risk (32.3%) than internal medicine clinics (20.3%). Only 27.1% of at-risk patients received nutritional support (surgical: 19%, internal medicine: 44%). Patients at risk of malnutrition exhibited significantly lower arm circumference (p: 0.000), calf circumference (p: 0.002), lymphocyte counts (p: 0.000), hemoglobin (p: 0.018), albumin (p: 0.001), and BMI (p: 0.038), as well as significantly higher age (p: 0.000) and CRP levels (p: 0.000). Conclusions: Nutritional support remains inadequate despite increased attention to malnutrition. Intensified nutrition education, particularly in surgical inpatient clinics, is needed to improve patient rehabilitation and outcomes.

29 April 2024 in Clinical Science of Nutrition
Verified
Journal Article
Open access
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GKGüldan Kahveci
Güldan Kahveci
EOEkmel Burak Ozsenel
Ekmel Burak Ozsenel
SBSema Basat
Sema Basat
Percutaneous endoscopic gastrostomy (PEG) is a safe, practical, and effective method for enteral nutrition. Minor and major complications may occur after the placement of a PEG tube. In the content of the education provided to caregivers, information should be given about the potential complications and the importance of communicating with the nutrition support team when these issues arise. In this case, we present a patient who was fed through a PEG tube and experienced infections and hypergranulation tissue processes during a thirty-seven-month follow-up, which included one tube replacement. Through this case, we aim to demonstrate that minor complications associated with the PEG tube can be addressed without hospitalization, through collaboration between the patient and the nutrition support team, allowing for an extended period of PEG tube usage.

12 March 2024 in Sakarya Medical Journal
Verified
Journal Article
Open access
EOEkmel Burak Ozsenel
Ekmel Burak Ozsenel
GKGüldan Kahveci̇
Güldan Kahveci̇
ZÇZuhal Çalişkan
Zuhal Çalişkan
SBSema Uçak Basat
Sema Uçak Basat
Background This study retrospectively evaluated the early and late complications of patients who had a percutaneous endoscopic gastrostomy (PEG) tube placed, discussed complication frequency of different diseases and finally pointed on some advices to reduce complications. Methods The study was conducted with 99 patients who had a PEG tube placed in the endoscopy unit of a training and research hospital. Patients’ age, gender, diagnosis, types of early and late complications, and complication development rates were evaluated. Results Mean age of the patients was 70.42±16.75(18-94) years and 48.5% were male. Early complications occurred in 11.1%, of which 6.05% were bleeding at the entry site of the PEG tube, and 5.05% were peristomal infection. 39.4% of the patients had late complications, including tube dislodgement in 18%, infection in 8.1%, aspiration pneumonia in 7.1% and other complications in 6%. No complications were observed in 51.5% of the patients, and early or late complications were observed in 48.5% of the patients. 2% of the patients had both early and late complications. The incidence of late complications was significantly higher in patients with Alzheimer’s disease (p=0.027). Conclusion In the follow-up of patients who had a PEG tube placed in the previous six months, the most common early complication was bleeding in 6.05%, and the most common late complication was tube dislodgement in 18%. Despite its potential complications, the PEG tube is a safe method for long-term enteral feeding. Alzheimer patients are at risk for late complications more than other diseases.

21 October 2026 in British Journal of Hospital Medicine
Verified
Journal Article
Open access
PDF file
NBNermin Mutlu Bilgiç
Nermin Mutlu Bilgiç
GKGüldan Kahveci
Güldan Kahveci
HAHüseyin Aykut
Hüseyin Aykut
EOEkmel Burak Ozsenel
Ekmel Burak Ozsenel
BÖBeytullah Özcan
Beytullah Özcan
SBSema Basat
Sema Basat
Aims/Background: Percutaneous endoscopic gastrostomy (PEG) provides long-term enteral access in selected older palliative-care inpatients, but its clinical value depends on prognosis, post-procedure trajectory, and recurrent tube-related interventions. This study aimed to evaluate PEG utilisation, repeat PEG-related procedural burden, and post-PEG outcomes among palliative-care inpatients aged 65 years or older at nutritional risk. Methods: This retrospective single-centre cohort included older palliative-care inpatients who underwent PEG placement or PEG-related procedures between January 2020 and December 2025. Among patients with available Nutrition Risk Screening 2002 (NRS-2002) screening data, all met the standard nutritional-risk threshold (score ≥3). The primary outcome was 90-day all-cause mortality after the index PEG date. Kaplan-Meier methods, univariable comparisons, parsimonious logistic regression, and a 90-day censored Cox model were used. Missing-data denominators, survival follow-up availability, and multicollinearity diagnostics were reported. Results: The analytic cohort included 141 patients aged 65 years or older; median age was 82.0 years (range 65–112), 60.3% were aged ≥80 years, and 60.3% were female. NRS-2002 score was ≥5 in 84 of 138 patients (60.9%), and serum albumin was <30 g/L in 110 of 141 patients (78.0%). Overall, 181 PEG-related procedures were recorded, and repeat PEG-related procedures occurred in 23 patients (16.3%). Valid survival follow-up was available for 105 patients. Kaplan-Meier mortality estimates were 5.7% at 30 days, 25.7% at 90 days, 43.8% at 180 days, and 53.3% at 365 days; median post-PEG survival was 326 days. In multivariable models, age, lower albumin, and log2-transformed NLR were not statistically significant independent predictors of 90-day mortality. Conclusion: Older palliative-care inpatients undergoing PEG placement or PEG-related procedures had substantial nutritional risk, early and 365-day mortality, and measurable repeat-procedure burden. Findings support cautious, goal-oriented PEG decision-making rather than causal inference about procedural benefit.