Sonia Herrero-Álvarez

Dr. Sonia Herrero-Álvarez

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 March 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
AUAngela Sada Urmeneta
Angela Sada Urmeneta
MTManuel J. Tousidonis
Manuel J. Tousidonis
Carlos Navarro CuéllarCarlos Navarro Cuéllar
Carlos Navarro Cuéllar
SOSantiago Ochandiano
Santiago Ochandiano
ICIgnacio Navarro Cuéllar
Ignacio Navarro Cuéllar
JSJosé Ignacio Salmerón
José Ignacio Salmerón
Introduction: The COVID-19 pandemic has induced profound societal and healthcare transformations globally. Material and methods: This multicenter retrospective study aimed to assess potential shifts in the epidemiology and management of oromaxillofacial trauma requiring surgical intervention over a 1-year period encompassing the onset of the COVID-19 pandemic, in comparison to the preceding year. The parameters investigated included age, sex, injury mechanisms, fractured bones, and treatment modalities. The statistical significance was set at p < 0.05. Results: A notable 39.36% reduction in oromaxillofacial fractures was identified (p < 0.001), with no significant alterations in sex distribution, types of fractured bones, or treatment modalities. An appreciable increase in mean age was observed (35.92 vs. 40.26) (p = 0.006). Analysis of the causes of oromaxillofacial trauma revealed diminished incidents of interpersonal violence (41% vs. 35%) and sports-related injuries (14% vs. 8%), alongside an escalation in cases attributed to falls (27% vs. 35%), precipitation events (2% vs. 5%), and traffic accidents (12% vs. 13%). The mandible emerged as the most frequently fractured bone. Conclusion: In conclusion, the COVID-19 pandemic has decreased the number of maxillofacial fractures treated surgically and has changed the epidemiology and the etiology of facial traumas.

22 February 2025 in Journal of Cranio-Maxillofacial Surgery
Verified
Journal Article
Closed access
MBMaitê Bertotti
Maitê Bertotti
LMLuis Otávio Carvalho de Moraes
Luis Otávio Carvalho de Moraes
OCOscar De la Sen Corcuera
Oscar De la Sen Corcuera
SHSonia Herrero-Álvarez
Sonia Herrero-Álvarez
CACarlota Mazo Amoros
Carlota Mazo Amoros
RMRafael Martin-Granizo
Rafael Martin-Granizo

31 May 2025 in Cancers
Verified
Journal Article
Open access
PDF file
FFFarzin Falahat
Farzin Falahat
SÁSonia Herrero Álvarez
Sonia Herrero Álvarez
JGJoaquín Calatayud Gastardi
Joaquín Calatayud Gastardi
EVElena Vara
Elena Vara
CACarlota Mazo Amoros
Carlota Mazo Amoros
AGAna-María Gómez-Martínez
Ana-María Gómez-Martínez
Background/objectives: Second primary lung cancer frequently manifests in individuals who have survived head and neck cancer, with this occurrence often being attributed to shared risk factors. The objective of the present study is to compare the prognosis, in terms of survival rate, of patients who presented isolated bronchogenic carcinoma (BC) with that of patients who presented with a personal history of BC and associated oropharyngeal and oral cancer (OAOC). Methods: A retrospective longitudinal study was conducted, including all consecutive patients who underwent surgical resection with curative intent for BC in Hospital Clínico San Carlos (HCSC), Madrid, Spain, between December 1989 and December 2024. The survival rate was calculated and compared in two groups of patients: Group 1: 1594 patients with isolated BC and Group 2: 97 patients with BC and OAOC. Results: Group 2 did not show a significant difference in their 60-month survival rate in comparison to Group 1 (HR = 1.23, CI 95% 0.9–1.6) p = 0.14. But when comparing the 120-month survival rate, Group 1 showed a significantly higher survival rate (36.4%, CI 95% 33.9–39%) compared to Group 2, (25.54%, CI 95% 17.78–36.7%) HR= 1.28 (CI 95% 1–1.6), p = 0.04. Disease-free survival showed a non-significant trend of greater severity among patients with a previous history of OAOC. Conclusions: Lung cancer patients who presented with OAOC had worse overall survival compared to patients who presented with isolated lung cancer, and a significant difference was observed at 120 months of follow-up.

3 September 2026 in Cancers
Verified
Journal Article
Open access
PDF file
FFFarzin Falahat
Farzin Falahat
SHSonia Herrero-Álvarez
Sonia Herrero-Álvarez
EMElisa María Molanes-López
Elisa María Molanes-López
RLroy Camacho Leone
roy Camacho Leone
Carlos Alfredo Fraile OliveroCarlos Alfredo Fraile Olivero
Carlos Alfredo Fraile Olivero
AGAna-María Gómez-Martínez
Ana-María Gómez-Martínez
Background/Objectives: Surgical pulmonary resection in lung cancer remains the cornerstone of curative treatment; however, it is associated with considerable postoperative pulmonary complications. Patients previously treated for head and neck cancer (HNC) have a significantly increased risk of developing second primary lung cancer (LC) and a higher incidence of adverse pulmonary outcomes after LC resective surgery due to increased baseline frailty. Methods: A retrospective observational longitudinal study was conducted on 1679 patients who underwent surgical resection with curative intent for LC at the Thoracic Surgery Department of Hospital Clínico San Carlos, Madrid, Spain, between December 1989 and December 2024. Patients were divided into two groups based on the presence or absence of prior HNC: 87 with HNC vs. 1592 without. Special attention was paid to respiratory complications, particularly bronchopleural fistula (BPF), empyema, atelectasis, and pneumonia. Variables significantly associated with BPF and HNC in univariate analyses (excluding those related to other complications to avoid collinearity), as well as clinically relevant baseline differences between groups, were included in a stepwise multivariable logistic regression modeling procedure to identify independent risk factors associated with BPF. Results: In comparison with the control group, significantly higher rates of postoperative BPF (12.6% vs. 3.6%), empyema (10.3% vs. 2.8%), atelectasis (14.9% vs. 8.3%) and need of reintervention (10.3% vs. 4.2%) were found in the HNC group under unadjusted approach and stratified by surgery period. Sex, history of HNC, chronic obstructive pulmonary disease (COPD) and length of preoperative hospital stay were independently associated with BPF according to several multivariable logistic regression fits, which showed a moderate discriminatory capacity (AUC values ranging from 0.723 to 0.732). In particular, the presence of HNC was significantly associated with BPF, with adjusted odds ratio (aOR) estimates ranging from 3.562 (95% CI: 1.773 to 7.156) to 3.789 (95% CI: 1.863 to 7.709). Conclusions: In our study, COPD, male sex, preoperative hospital stay as well as HNC history were found independently associated with an increased odds of BPF after surgical treatment for LC. In particular, patients previously treated for HNC had more than threefold higher odds of developing BPF than those without a history of HNC, with this association remaining consistent over the 35-year study period.

7 June 2023 in Preprints.org
Verified
Preprint
Open access
PDF file
AUAngela Sada Urmeneta
Angela Sada Urmeneta
JSJosé Ignacio Salmerón
José Ignacio Salmerón
Carlos Navarro CuéllarCarlos Navarro Cuéllar
Carlos Navarro Cuéllar
EOEduardo Olavarria
Eduardo Olavarria
GSGregorio Sanchez-Aniceto
Gregorio Sanchez-Aniceto
MTManuel J. Tousidonis
Manuel J. Tousidonis
The Covid-19 pandemic has produced a change in the way of living, socializing and a modification in Health Systems around the world. A multicentre retrospective study was carried out to study orofacial trauma in one of the regions most affected during the first wave of the pandemic, with the participation of the five main tertiary hospitals in Madrid. The aim of this study is to evaluate the epidemiology of orofacial surgical trauma during the 1 year of COVID pandemic and compared to de prior year. Age, sex, mechanism, localization, and treatment were studied. P-value <0.05 was considered statically significative. Reduction of 39.36% (<0.001) in maxillofacial fractures was observed, without significance change in sex, localization or treatment. Significant increase in age (35,92 vs. 40,26) (p = 0.006) was observed. Significant decline in mechanism was noted (p = 0.025), decreasing personal violence (41% vs 35%) and sports (14% vs 8%); increasing in falls (27% vs 35%), precipitation (2 vs 5%), and traffic accidents (12% vs 13%). The mandible was the most frequent fractured bone. The COVID pandemic has produced epidemiological variations in orofacial trauma, making it necessary to monitor social and legal changes that may require reorganization to adjust to population needs.