Background: IgE‐mediated food allergy (FA) is a global health concern with substantial individual and societal implications. While diverse intervention strategies have been researched, inconsistencies in reported outcomes limit evaluations of FA treatments. To streamline evaluations and promote consistent reporting, the Core Outcome Measures for Food Allergy (COMFA) initiative aimed to establish a Core Outcome Set (COS) for FA clinical trials and observational studies of interventions.Methods: The project involved a review of published clinical trials, trial protocols and qualitative literature. Outcomes found as a result of review were categorized and classified, informing a two‐round online‐modified Delphi process followed by hybrid consensus meeting to finalize the COS.Results: The literature review, taxonomy mapping and iterative discussions with diverse COMFA group yielded an initial list of 39 outcomes. The iterative online and in‐person meetings reduced the list to 13 outcomes for voting in the formal Delphi process. One more outcome was added based on participant suggestions after the first Delphi round. A total of 778 participants from 52 countries participated, with 442 participating in both Delphi rounds. No outcome met a priori criteria for inclusion, and one was excluded as a result of the Delphi. Thirteen outcomes were brought to the hybrid consensus meeting as a result of Delphi and two outcomes, ‘allergic symptoms’ and ‘quality of life’ achieved consensus for inclusion as ‘core’ outcomes.Conclusion: In addition to the mandatory reporting of adverse events for FA clinical trials or observational studies of interventions, allergic symptoms and quality of life should be measured as core outcomes. Future work by COMFA will define how best to measure these core outcomes.
Background: The COVID-19 pandemic has affected the supply, cost, and demand for certain foods, but it is not clear how these changes have affected food-allergic households.Objective: To describe the changes in food-related costs that have followed COVID-19, as reported by higher- and lower-income households with a food-allergic member.Methods: Between May 1-June 30, 2020, Canadian households, with at least one food-allergic member, completed an online survey on food shopping and preparation habits before and during the COVID-19 pandemic. The sample was divided into binary groups, either higher or lower than the sample median income. Data were analyzed using descriptive statistics and multiple regression.Results: The sample was comprised of 102 participants (i.e., 51/ income group). The three most common food allergies amongst both groups were peanuts, tree nuts and milk. Since the start of the pandemic, both groups reported greater monthly direct grocery costs, although costs amongst the higher-income group were twice as high as the lower-income group ($212.86 vs. $98.89, respectively). Indirect food preparation costs were similarly elevated. Higher-income households with food procurement difficulties reported increased indirect shopping costs following the outbreak of COVID-19, whereas those without such difficulties reported decreased costs. Lower-income households with allergies to milk, wheat, or eggs (i.e., staple allergy) experienced a larger change in indirect food preparation costs following the outbreak of COVID-19 relative to those with other food allergies ($244.58 vs. –$20.28, respectively; p = 0.03).Conclusion: Both higher and lower income households with food allergy reported greater direct food costs and indirect food preparation costs following the COVID-19. Households with staple allergy and those with difficulties finding their typical food items were particularly affected.
28 March 2023 in Current Opinion in Allergy and Clinical Immunology
Purpose of review: To provide an overview of the magnitude and sources of food allergy-related costs, with a particular emphasis on the recent literature. We also aim to identify clinical and demographic factors associated with differences in food allergy-related costs. Recent findings: Recent research has expanded upon previous studies by making greater use of administrative health data and other large sample designs to provide more robust estimates of the financial burden of food allergy on individuals and the healthcare system. These studies shed new light on the role of allergic comorbidities in driving costs, and also on the high costs of acute food allergy care. Although research is still largely limited to a small group of high-income countries, new research from Canada and Australia suggests that the high costs of food allergy extend beyond the United States and Europe. Unfortunately, as a result of these costs, newly emerging research also suggests that individuals managing food allergy, may be left at greater risk of food insecurity. Summary: Findings underscore the importance of continued investment in efforts aimed at reducing the frequency and severity of reactions, as well as programs designed towards helping offset individual/household level costs.
Caregivers of children with chronic conditions face daily challenges and a lower quality of life, which may be improved through peer support. This scoping review explored the literature on formal caregiver-to-caregiver mentorship programs, identifying strategies to inform future programs. Using Arskey and O’Malley’s framework, we searched five databases for peer-reviewed literature on caregiver-to-caregiver mentorship programs for adult caregivers caring for children (≤18 years) with chronic conditions. Thematic analysis was performed on relevant articles. Of the 10 064 search hits, 109 were included after full-text screening. Theme 1, “Mentorship adds to medical support”, reflected how mentorship can complement medical care provided by healthcare teams. Theme 2, “Successful mentorship requires the right mentors”, highlighted the qualities of mentors crucial for effective mentorship, mentor-matching practices, and training areas for mentors. Theme 3, “Mentorship programs should balance structure and flexibility”, emphasized the importance of allowing for flexibility to accommodate diverse family needs. Theme 4, “Mentorship programs face common challenges”, summarized the challenges frequently faced when implementing mentorship programs. The study findings suggest that the success of mentorship programs hinge on factors including a flexible program structure, knowledgeable and dedicated mentors, and an infrastructure in place for supporting both the mentors and the financial needs of the program.