This article delves into the interplay of neglected tropical diseases (NTDs) and Sustainable Development Goals (SDGs) within Africa, spotlighting gender disparities in NTD programs. NTDs, impacting marginalized communities, impose considerable physical, mental, and social burdens. The article underscores NTDs as equity markers for SDGs, spotlighting gender‐based imbalances in disease susceptibility, treatment accessibility, and health‐seeking tendencies. Gender's influence on NTD risks is elucidated, emphasizing the heightened susceptibility of women due to socioeconomic constraints, cultural dynamics, and gender norms. The article also highlights the absence of gender considerations in NTD programs, advocating for gender‐integrated strategies, enhanced data collection, and collaborative partnerships to rectify these inequities. By embracing a gender‐equity approach, the article underscores the necessity of gender‐balanced NTD efforts for comprehensive health, sustainable development, and gender parity, demanding cohesive actions across sectors.