Esmee Cerfonteijn

Ms. Esmee Cerfonteijn


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 June 2025 in Bioengineering
Verified
Journal Article
Open access
PDF file
ESEsther van Santbrink
Esther van Santbrink
VSValérie Schuermans
Valérie Schuermans
ECEsmee Cerfonteijn
Esmee Cerfonteijn
MBMarcel Breeuwer
Marcel Breeuwer
ASAnouk Y.J.M. Smeets
Anouk Y.J.M. Smeets
TBToon Boselie
Toon Boselie
Background: Qualitative motion analysis revealed that the cervical spine moves according to a consistent pattern. This analysis calculates the relative rotation between vertebral segments to determine the sequence in which they contribute to extension, demonstrating a mean sensitivity of 90% and specificity of 85%. However, the extensive time that is required limits its applicability. This study investigated the feasibility of implementing a deep-learning model to analyze qualitative cervical motion. Methods: A U-Net architecture was implemented as 2D and 2D+t models. Dice similarity coefficient (DSC) and Intersection over Union (IoU) were used to assess the performance of the models. Intraclass Correlation Coefficient (ICC) was used to compare the relative rotation of individual vertebrae and segments to the ground truth. Results: IoU ranged from 0.37 to 0.74 and DSC ranged from 0.53 to 0.80. The ICC scores for relative rotation ranged from 0.62 to 0.96 for individual vertebrae and from 0.28 to 0.72 for vertebral segments. For segments, 2D+t models presented higher ICC scores compared to 2D models. Conclusions: This study showed the feasibility of implementing deep-learning models to analyze qualitative cervical motion in dynamic X-ray recordings. Future research should focus on improving model segmentation by enhancing recording contrast and applying post-processing methods. Improved segmentation accuracy will enable routine use of the analysis of motion patterns in clinical research. The absence or presence of a motion pattern, or identification of new patterns has the potential to aid in clinical decision-making.

13 May 2025 in Preprints.org
Verified
Preprint
Open access
PDF file
ESEsther van Santbrink
Esther van Santbrink
VSValérie Schuermans
Valérie Schuermans
ECEsmee Cerfonteijn
Esmee Cerfonteijn
MBMarcel Breeuwer
Marcel Breeuwer
ASAnouk Y.J.M. Smeets
Anouk Y.J.M. Smeets
TBToon Boselie
Toon Boselie
Background: Qualitative motion analysis revealed that the cervical spine moves according to a consistent pattern. This analysis calculates the relative rotation between vertebral segments to determine the sequence in which they contribute to extension, demonstrating high sensitivity and specificity. However, the extensive time required limits its applicability. This study investigated the feasibility of implementing a deep-learning model to analyze qualitative cervical motion. Methods: A U-Net architecture was implemented as 2D and 2D+t models. Dice similarity coefficient (DSC) and Intersection over Union (IoU) were used to assess the performance of the models. Intraclass Correlation Coefficient (ICC) was used to compare the relative rotation of individual vertebrae and segments to the ground truth. Results: IoU ranged from 0.37 to 0.74 and DSC ranged from 0.53 to 0.80. The ICC scores for relative rotation ranged from 0.62 to 0.96 for individual vertebrae and from 0.28 to 0.72 for vertebral segments. For segments, 2D+t models presented higher ICC scores compared to 2D models. Conclusion: This study showed the feasibility of implementing deep-learning models to analyze qualitative cervical motion in dynamic X-ray recordings. Future research should focus on improving model segmentation by enhancing recording contrast and applying post-processing methods.