Adriana Maria Canciu

Ms. Adriana Maria Canciu


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
12 November 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
Adriana Maria CanciuAdriana Maria Canciu
Adriana Maria Canciu
APAlina Liliana Pintea
Alina Liliana Pintea
CDCosmina Diaconu
Cosmina Diaconu
FPFlorina Ligia Popa
Florina Ligia Popa
HDHorațiu-Paul Domnariu
Horațiu-Paul Domnariu
CDCarmen Daniela Domnariu
Carmen Daniela Domnariu
Background/Objectives: Post-stroke disability is a prevalent complication in patients who have experienced a stroke. It is imperative that patients suffering from associated disability be hospitalised in rehabilitation wards, with a view to minimising their disability. The primary objective of the present study is to analyse the direct medical costs associated with the rehabilitation of patients with post-stroke disability who are admitted to a rehabilitation clinic for the first time. Methods: This retrospective study was conducted in a public hospital in Romania between January 2021 and December 2024. Patient information was retrieved from the hospital database and included the following: socio-demographic and clinical characteristics; disability score assessed using the modified Rankin scale (mRS); number of days of hospitalisation; and direct medical costs related to hospitalisation. Results: A total of 584 patients were included in this study. The average age was 68.04 years, 82% had suffered an ischaemic stroke, and 18% had suffered a haemorrhagic stroke. The mRS disability scores for ischaemic stroke were 2 (28.54%); 3 (24.79%); 4 (30.41%); and 5 (16.25%). The mRS scores for haemorrhagic stroke were 4 (33.65%); 5 (29.80%); 3 (20.19%); and 2 (16.34%). Hypertension was present in 80% of patients. The average length of hospital stay was 12.44 days. The total cost of hospitalisation per patient averaged RON 5295.33 thousand (approximately EUR 1031). Pearson’s correlation indicates a statistically significant positive association between higher mRS disability scores and higher hospitalisation costs (p < 0.001). Conclusions: The financial burden imposed on healthcare systems in Romania by medical expenses related to the rehabilitation of patients with post-stroke disability is significant. It is imperative to implement measures that will reduce the financial burden associated with hospitalising these patients and minimise the duration of their hospital stay.

13 November 2025 in Applied Sciences
Verified
Journal Article
Open access
PDF file
MTMihaela Adriana Tiţa
Mihaela Adriana Tiţa
Adelina Maria ConstantinescuAdelina Maria Constantinescu
Adelina Maria Constantinescu
CGCecilia Georgescu
Cecilia Georgescu
Adriana Maria CanciuAdriana Maria Canciu
Adriana Maria Canciu
MIMaria Lidia Iancu
Maria Lidia Iancu
TITA OVIDIUTITA OVIDIU
TITA OVIDIU
(1) Background: Research into incorporating plant powders into dairy products is growing because they significantly increase the nutritional value of the finished products, making them a more attractive option for consumers seeking healthier alternatives. The objective of this study is to develop a novel dairy product by incorporating camu-camu powder into fresh cow’s cheese. The material has been identified as a promising candidate due to its multiple health benefits and high antioxidant content, particularly vitamin C; (2) Methods: The stability of the product during storage was therefore evaluated by analysing its acidity, pH, dry matter content, water activity, syneresis and water holding capacity. The impact of camu-camu powder on the antioxidant activity of the cheese samples was determined using the DPPH method. A sensory evaluation was conducted to ascertain the potential functional properties and consumer acceptability of the subject; (3) Results: The bioactive compounds present in the powder have been shown to enhance the antioxidant capacity of fresh cheese, with the 2% sample demonstrating the most effective antioxidant performance. From a sensory perspective, the 1.5% sample received the highest ratings from tasters. The 1% sample is distinguished by its notable colour stability during storage. Physicochemical analysis shows that camu-camu powder is a sustainable ingredient that improves the quality and extends the shelf life of the finished product; (4) Conclusions: This information is indispensable for the evaluation of the safety and efficacy of camu-camu powder in dairy products. Moreover, it may serve as a point of departure for future studies involving the development of other food products with bioactive compounds using unconventional raw materials.

12 October 2026 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
CDCosmina Diaconu
Cosmina Diaconu
AVAnca Vidrighin
Anca Vidrighin
EPEmi Marinela Preda
Emi Marinela Preda
CDCRISTINEL GABRIEL DIACONU
CRISTINEL GABRIEL DIACONU
CDCarmen Daniela Domnariu
Carmen Daniela Domnariu
Corina PorrCorina Porr
Corina Porr
Nail-patella syndrome (NPS) is a rare autosomal dominant multisystem disorder characterized by a variable combination of nail abnormalities, patellar hypoplasia or dysplasia, elbow involvement, and iliac horns, with possible renal, ophthalmological, neurological, and skeletal manifestations. Recognition may be substantially delayed when individual abnormalities are assessed separately or attributed to age-related and degenerative musculoskeletal disease. We report the case of a 76-year-old woman evaluated for progressive bilateral knee pain, gait impairment, and chronic multisite musculoskeletal symptoms. Congenital thumbnail abnormalities and long-standing restriction of elbow extension had been present since childhood. Suspicion of NPS was first raised at the age of 43 years after bilateral iliac horns were identified radiographically in one of her grandsons. Clinical examination demonstrated bilateral thumbnail hypoplasia with partial absence of the ulnar nail plate, triangular lunulae, reduced dorsal distal interphalangeal creases, bilateral fifth-finger flexion contractures, marked limitation of elbow extension with restricted pronation and supination, and clinically hypoplastic patellae. Bilateral Lester sign and glaucoma were also documented. Radiographic assessment revealed bilateral patellar hypoplasia, lateral displacement of the left patella, bilateral knee osteoarthritis, and characteristic bilateral iliac horns. Additional findings included bilateral hip osteoarthritis, lumbar degenerative changes, pes planus, a bifid configuration of the left fifth metatarsal, osteopenia, and sensory abnormalities. Walking pain was 70 mm on a 100-mm visual analogue scale, and the WOMAC score was 42/96. Following a 10-day rehabilitation program, walking pain decreased from 70 to 50 mm on the visual analogue scale, while the WOMAC total score improved from 42/96 to 37/96, indicating short-term symptomatic and functional improvement. Routine urinalysis showed no proteinuria or hematuria. Molecular testing for a pathogenic LMX1B variant was not performed. The diagnosis was established on the basis of the highly characteristic integrated clinical and radiographic phenotype. This case illustrates how NPS may remain incompletely recognized for decades despite congenital manifestations and emphasizes the clinical value of pattern recognition across multiple organ systems. In particular, the coexistence of characteristic nail changes, patellar abnormalities, elbow involvement, and bilateral iliac horns should prompt consideration of NPS and appropriate multidisciplinary surveillance.