The increasing prevalence of diet-related diseases calls for an improvement in nutritional advice. Personalized nutrition aims to solve this problem by adapting dietary and lifestyle guidelines to the unique circumstances of each individual. With the latest advances in technology and data science, researchers can now automatically collect and analyze large amounts of data from a variety of sources, including wearable and smart devices. By combining these diverse data, more comprehensive insights of the human body and its diseases can be achieved. However, there are still major challenges to overcome, including the need for more robust data and standardization of methodologies for better subject monitoring and assessment. Here, we present the AI4Food database (AI4FoodDB), which gathers data from a nutritional weight loss intervention monitoring 100 overweight and obese participants during 1 month. Data acquisition involved manual traditional approaches, novel digital methods and the collection of biological samples, obtaining: (i) biological samples at the beginning and the end of the intervention, (ii) anthropometric measurements every 2 weeks, (iii) lifestyle and nutritional questionnaires at two different time points and (iv) continuous digital measurements for 2 weeks. To the best of our knowledge, AI4FoodDB is the first public database that centralizes food images, wearable sensors, validated questionnaires and biological samples from the same intervention. AI4FoodDB thus has immense potential for fostering the advancement of automatic and novel artificial intelligence techniques in the field of personalized care. Moreover, the collected information will yield valuable insights into the relationships between different variables and health outcomes, allowing researchers to generate and test new hypotheses, identify novel biomarkers and digital endpoints, and explore how different lifestyle, biological and digital factors impact health. The aim of this article is to describe the datasets included in AI4FoodDB and to outline the potential that they hold for precision health research. Database URL https://github.com/AI4Food/AI4FoodDB

In chronic respiratory diseases (CRDs), oxidative stress and inflammation are closely linked, driving disease onset, progression, and comorbidities. Oxidative stress activates inflammatory pathways, while chronic inflammation promotes further reactive oxygen species (ROS) production, creating a vicious cycle leading to airway remodeling, reduced lung function, and exacerbations. This review highlights the central roles of inflammation and oxidative stress in chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA). In COPD, chronic hypoxemia associates with emphysema, appearing with disease progression. In OSA, beyond systemic consequences, pulmonary inflammation and oxidative stress contribute to lung injury as well. Although COPD and OSA are distinct conditions, some patients present with “overlap syndrome”, a term used in this review to describe the coexistence of both. This combination poses unique diagnostic and therapeutic challenges. We also examine the role of hypoxia and its transcriptional effects via hypoxia-inducible factors (HIFs) in promoting oxidative stress and inflammation. Finally, we explore how artificial intelligence (AI) offers promising tools to improve diagnosis, monitoring, and management of CRDs and may help elucidate mechanistic links between hypoxia, inflammation, and oxidative stress, contributing to more personalized therapeutic strategies.

This work introduces an innovative method for estimating attention levels (cognitive load) using an ensemble of facial analysis techniques applied to webcam videos. Our method is particularly useful, among others, in e-learning applications, so we trained, evaluated, and compared our approach on the mEBAL2 database, a public multi-modal database acquired in an e-learning environment. mEBAL2 comprises data from 60 users who performed 8 different tasks. These tasks varied in difficulty, leading to changes in their cognitive loads. Our approach adapts state-of-the-art facial analysis technologies to quantify the users’ cognitive load in the form of high or low attention. Several behavioral signals and physiological processes related to the cognitive load are used, such as eyeblink, heart rate, facial action units, and head pose, among others. Furthermore, we conduct a study to understand which individual features obtain better results, the most efficient combinations, explore local and global features, and how temporary time intervals affect attention level estimation, among other aspects.We find that global facial features are more appropriate for multimodal systems using score-level fusion, particularly as the temporal window increases. On the other hand, local features are more suitable for fusion through neural network training with score-level fusion approaches. Our method outperforms existing state-of-the-art accuracies using the public mEBAL2 benchmark.

We present edBB-Demo, a demonstrator of an AI-powered research platform for student monitoring in remote education. The edBB platform aims to study the challenges associated to user recognition and behavior understanding in digital platforms. This platform has been developed for data collection, acquiring signals from a variety of sensors including keyboard, mouse, webcam, microphone, smartwatch, and an Electroencephalography band. The information captured from the sensors during the student sessions is modelled in a multimodal learning framework. The demonstrator includes: i) Biometric user authentication in an unsupervised environment; ii) Human action recognition based on remote video analysis; iii) Heart rate estimation from webcam video; and iv) Attention level estimation from facial expression analysis.

This work presents the IMPROVE dataset, a multimodal resource designed to evaluate the effects of mobile phone usage on learners during online education. It includes behavioral, biometric, physiological, and academic performance data collected from 120 learners divided into three groups with different levels of phone interaction, enabling the analysis of the impact of mobile phone usage and related phenomena such as nomophobia. A setup involving 16 synchronized sensors—including EEG, eye tracking, video cameras, smartwatches, and keystroke dynamics—was used to monitor learner activity during 30-minute sessions involving educational videos, document reading, and multiple-choice tests. Mobile phone usage events, including both controlled interventions and uncontrolled interactions, were labeled by supervisors and refined through a semi-supervised re-labeling process. Technical validation confirmed signal quality, and statistical analyses revealed biometric changes associated with phone usage. The dataset is publicly available for research through GitHub and Science Data Bank, with synchronized recordings from three platforms (edBB, edX, and LOGGE), provided in standard formats (.csv, .mp4, .wav, and .tsv), and accompanied by a detailed guide.