1. The addition of yeast cell wall (YCW) mannan fractions or low concentrations of antibiotics to the diet of broilers positively affects gut health by improving intestinal cell morphology and improves feed efficiency and performance; however the exact mechanisms are unclear. Based on these production responses, the objective of this study was to compare the effects of supplementing YCW and bacitracin methylene disalicylate (BMD) in the diet on mRNA levels in the jejunum of 6-week-old broilers. 2. Dietary treatments were a maize-soya control diet and the control diet with the addition of YCW or BMD. Birds (n = 7) from each dietary treatment were randomly selected and killed at d 42. Whole jejunum (with serosa) samples were collected for RNA isolation. Gene expression analysis was performed using the AffymetrixGeneChip Chicken Genome Array (Santa Clara, CA, USA). 3. Supplementation with YCW resulted in 928 genes that were significantly changed (456 down-regulated, 472 up-regulated) and supplementation with BMD resulted in 857 genes that significantly changed (408 down-regulated, 449 up-regulated). In addition, 316 genes were significantly changed by both YCW and BMD (146 down-regulated, 170 up-regulated). 4. BMD increased the expression of genes involved in lipid and carbohydrate metabolism and decreased expression of genes associated with T-helper cell pathways. Gene expression profiles from birds fed on diets containing YCW showed changes on a genomic level that correspond to slower gut cell turnover and therefore increased energy preservation for growth. 5. In conclusion, supplementation with BMD or YCW had similar influences on the number of differentially expressed genes in the jejunum. Biological functions common to both YCW and BMD with positive activation scores included antiviral response and antimicrobial response. Genes that were affected by BMD or YCW classified into both different and common biological functions and pathways related to improved metabolism and health in the jejunum.
23 November 2022 in Geochemistry, Geophysics, Geosystems
Inclination is the angle of a magnetization vector from horizontal. Clastic sedimentary rocks often experience inclination shallowing whereby syn‐ to post‐depositional processes result in flattened detrital remanent magnetizations relative to local geomagnetic field inclinations. The deviation of recorded inclinations from true values presents challenges for reconstructing paleolatitudes. A widespread approach for estimating flattening factors (f) compares the shape of an assemblage of magnetization vectors to that derived from a paleosecular variation model (the elongation/inclination [E/I] method). Few studies exist that compare the results of this statistical approach with empirically determined flattening factors and none in the Proterozoic Eon. In this study, we evaluate inclination shallowing within 1.1 billion‐year‐old, hematite‐bearing red beds of the Cut Face Creek Sandstone that is bounded by lava flows of known inclination. Taking this inclination from the volcanics as the expected direction, we found that detrital hematite remanence is flattened with whereas the pigmentary hematite magnetization shares a common mean with the volcanics. Using the pigmentary hematite direction as the expected inclination results in . These flattening factors are consistent with those estimated through the E/I method supporting its application in deep time. However, all methods have significant uncertainty associated with determining the flattening factor. This uncertainty can be incorporated into paleomagnetic poles with the resulting ellipse approximated with a Kent distribution. Rather than seeking to find “the flattening factor,” or assuming a single value, the inherent uncertainty in flattening factors should be recognized and incorporated into paleomagnetic syntheses.
The Ouarzazate Group in the Anti-Atlas Belt of southern Morocco, part of the West African Craton (WAC), is a significant Proterozoic lithostratigraphic unit formed during the late Ediacaran period. It includes extensive volcanic rocks associated with the early stages of Iapetus Ocean opening. Zircon U-Pb dating and geochemical analyses of the Oued Dar’a Caldera (ODC) volcanic succession in the Saghro Massif reveal two major eruptive cycles corresponding to the lower and upper Ouarzazate Group. The 1st cycle (588–563 Ma) includes pre- and syn-caldera volcanic succession characterized by basaltic andesite to rhyolitic rocks, formed in a volcanic arc setting through lithospheric mantle-derived mafic magmatism and crustal melting. A major caldera-forming eruption occurred approximately 571–562 Ma, with associated rhyolitic dyke swarms indicating a larger caldera extent than previously known. The 2nd cycle (561–543 Ma) features post-caldera bimodal volcanism, with tholeiitic basalts and intraplate felsic magmas, signaling a shift to continental flood basalts and silicic volcanic systems. The entire volcanic activity spans approximately 23–40 million years. This succession is linked to late Ediacaran intracontinental super-eruptions tied to orogenic collapse and continental extension, likely in association with the Central Iapetus Magmatic Province (CIMP), marking a significant transition in the geodynamic evolution of the WAC.
Paleogeography of the Ediacaran Period has remained poorly understood because of paleomagnetic studies commonly yielding perplexing or conflicting data. Here, we report new magnetostratigraphic data from the Ediacaran Ouarzazate Group in the Anti-Atlas Mountains of Morocco, which have primary magnetizations supported by a positive conglomerate test and stratigraphically consistent directions within volcanic units across multiple localities. Comprehensive magnetostratigraphic sampling shows highly variable directions, consistent with a rapidly changing geomagnetic field along a longitudinally preferred band. High-precision geochronology constrains the geomagnetic variability to ~568 to 562 million years and suggests rates that are likely too rapid for true polar wander or plate tectonic interpretations. Comparison of igneous- and sedimentary-derived data, using a new statistical approach combining Bingham and Fisher distributions, indicates a high-inclination paleomagnetic direction that is compatible with independent evidence for regional glaciation. Our analysis produces a late Ediacaran paleogeographic reconstruction that is consistent with paleomagnetic and geologic constraints.
The paleogeography of Laurentia throughout the Neoproterozoic is critical for reconstructing global paleogeography due to its central position in the supercontinent Rodinia. We develop a new paleomagnetic pole from red siltstones and fine‐grained sandstones of the early Neoproterozoic Jacobsville Formation which is now constrained to be ca. 990 Ma in age. High‐resolution thermal demagnetization experiments resolve detrital remanent magnetizations held by hematite. These directions were reoriented within siltstone intraclasts and pass intraformational conglomerate tests—giving confidence that the magnetization is detrital and primary. An inclination‐corrected mean paleomagnetic pole position for the Jacobsville Formation indicates that Laurentia's motion slowed down significantly following the onset of the Grenvillian orogeny. Prior rapid plate motion associated with closure of the Unimos Ocean between 1,110 and 1,090 Ma transitioned to slow drift of Laurentia across the equator in the late Mesoproterozoic to early Neoproterozoic. We interpret the distinct position of this well‐dated pole from those in the Grenville orogen that have been assigned a similar age to indicate that the ages of the poles associated with the Grenville Loop likely need to be revised to be younger due to prolonged exhumation.
15 March 2025 in Journal of Geophysical Research: Solid Earth