FRANCISCO JAVIER RUBIO CASTAÑEDA

Dr. FRANCISCO JAVIER RUBIO CASTAÑEDA

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Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 January 2017
Verified
Journal Article
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FCFRANCISCO JAVIER RUBIO CASTAÑEDA
FRANCISCO JAVIER RUBIO CASTAÑEDA
CAConcepción Tomás Aznar
Concepción Tomás Aznar
CBCarmen Muro Baquero
Carmen Muro Baquero

1 December 2015 in Revista Espanola de Salud Publica
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FCFRANCISCO JAVIER RUBIO CASTAÑEDA
FRANCISCO JAVIER RUBIO CASTAÑEDA
CAConcepción Tomás Aznar
Concepción Tomás Aznar
CBCarmen Muro Baquero
Carmen Muro Baquero
JGJohanna Chico Guerra
Johanna Chico Guerra
People over 65 are the ones who have higher levels of functional limitations. There are many instruments to measure mobility in this age range that causes a lack of international consensus on what are the most suitable for this purpose. The aim is to analyze and identify which instruments provide greater data reliability and validity in measuring mobility in elderly people. Systematic review of the instruments used to measure mobility in people over 65 years published between 2001-2013, conducted in PubMed and Science Direct. The 34 items selected instruments were grouped into 4 categories: doubly labeled water (DLW), motion detectors, objective measures of mobility and questionnaires. We identified, 23 are questionnaires, 4 accelerometers, 3 to objective measures of mobility and 2 both pedometers as DLW. The other 2 to combined analysis of different instruments. We conclude that assessing objective and subjective data obtains the most accurate measures of mobility. To obtain objective data, objective measures of mobility will be opposed to pedometers and accelerometers, while questionnaires were selected for subjective data due to its ease of use and sociodemographic data that provides. Among these instruments, the Short Physical Performance Battery (SPPB) and Minnesota Leisure Time are the most appropriate instruments to estimate the mobility of the elderly in Spain.

10 October 2025 in Journal of Clinical Medicine
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Journal Article
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ELEmilia Ferrer López
Emilia Ferrer López
RBRaúl López Blasco
Raúl López Blasco
FCFRANCISCO JAVIER RUBIO CASTAÑEDA
FRANCISCO JAVIER RUBIO CASTAÑEDA
VLVíctor Cantin Lahoz
Víctor Cantin Lahoz
AJAguilón-Leiva Juan José
Aguilón-Leiva Juan José
FUFernando Urcola-Pardo
Fernando Urcola-Pardo
Background/Objectives: Weight gain after kidney transplantation is frequent but heterogeneous, often accompanied by changes in body composition that influence long-term outcomes. This study analysed one-year changes in body compartments and their demographic and clinical determinants. Methods: A prospective cohort of 112 adult kidney recipients transplanted between September 2020 and June 2022 at a Spanish tertiary hospital was followed. Body weight, muscle mass, fat mass, visceral fat and total body water were assessed by multi-frequency bioelectrical impedance at discharge, and at 3, 6 and 12 months. Associations with sociodemographic, clinical and comorbidity variables were examined using repeated-measures ANOVA and comparative tests. Results: At 12 months, mean weight gain was 3.6 ± 6.5 kg (5.1%). Increases were greater in men, younger patients, non-dialysis candidates, those with previous transplantation and living donor grafts. Muscle mass rose during the first three months and then stabilised, with greater gains in men and haemodialysis patients. Fat mass decreased initially and then increased, particularly in women, younger recipients and living donor transplants. Visceral fat progressively increased after three months, with higher levels in men and older patients. Total body water declined in women, younger recipients and first transplant patients. Patients with new-onset diabetes gained less weight, while smokers gained more. Conclusions: Post-transplant body composition is shaped by sex, age, BMI, comorbidities and donor type. Monitoring compartments beyond body weight may allow early detection of adverse metabolic trajectories. Tailored nutritional and lifestyle interventions are needed to optimise long-term outcomes.

30 June 2024 in Enfermería Nefrológica
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FCFRANCISCO JAVIER RUBIO CASTAÑEDA
FRANCISCO JAVIER RUBIO CASTAÑEDA
MNManuel Fernández Núñez
Manuel Fernández Núñez
ASAna Isabel Sierra Sánchez
Ana Isabel Sierra Sánchez
MSMaría Amaya Mateo Sánchez
María Amaya Mateo Sánchez
VLVíctor Cantin Lahoz
Víctor Cantin Lahoz
ELEmilia Ferrer López
Emilia Ferrer López
Introduction: Different first-generation methods exist for the detection of stenosis. Objective: To determine the accuracy of first-generation methods in detecting stenosis in native arteriovenous fistulas. Method: Retrospective observational study. Sample: Patients with functioning native arteriovenous fistulas. First-generation methods include physical examination, manual tests, pulse increase test and arm elevation test, indirect methods, Kt/V, and arteriovenous fistula recirculation. The diagnosis of stenosis was confirmed by Doppler ultrasound. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of first-generation methods based on Doppler ultrasound were calculated. Results: Sample 39 patients, 79.48% male. Ultrasound detected 19 stenoses, nonsignificant. Physical examination: sensitivity 31.5%, specificity 80%, PPV 60%, NPV 55.1%, accuracy 56.4%. Pulse rise test: sensitivity 5.2%, specificity 90%, PPV 33.3%, NPV 50%, accuracy 48.7%. Arm elevation test: sensitivity 52.6%, specificity 70%, PPV 62.5%, NPV 60.8%, accuracy 61.5%. Indirect methods: sensitivity 15.7%, specificity 55%, PPV 25%, NPV 40.7%, accuracy 35.9%. Kt/V: sensitivity 10.5%, specificity 75%, PPV 28.5%, NPV 46.8%, accuracy 43.5%. AVF recirculation: sensitivity 10.5%, specificity 100%, PPV 100%, NPV 54.1%, accuracy 56.4%. Conclusions: All first-generation methods have high specificity and low sensitivity. The degree of stenosis (significant or non-significant) could influence the sensitivity of the physical examination but not the specificity. The arm elevation test is the most accurate first-generation method of detecting stenosis.

30 December 2022 in Enfermería Nefrológica
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Journal Article
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FCFRANCISCO JAVIER RUBIO CASTAÑEDA
FRANCISCO JAVIER RUBIO CASTAÑEDA
MFManuel Fernández-Núñez
Manuel Fernández-Núñez
ASAna Isabel Sierra-Sánchez
Ana Isabel Sierra-Sánchez
VCVíctor Cantín-Lahoz
Víctor Cantín-Lahoz
EFEmilia Ferrer-López
Emilia Ferrer-López
MMMaría Amaya Mateo-Sánchez
María Amaya Mateo-Sánchez
Introduction: Doppler ultrasound and dilutional methods allow monitoring of vascular access flow. The presence of collateral veins may influence the determination of vascular access flow.Objective: To determine the influence of collateral veins on the vascular access flow measurement by Doppler ultrasound and by the thermodilution method. Material and Method: Observational and prospective study. Native arteriovenous fistulas that met the selection criteria were selected. An annual measurement of vascular access flow by Doppler ultrasound and two quarterly thermodilution measurements (thermodilution-1 and thermodilution-2) were performed. Ultrasound was used to determine the presence of collateral veins.Results: Thirty-eight native arteriovenous fistulae were analysed. Males accounted for 78.9% of the sample. Collateral veins were present in 23.6% of cases. Analysing the whole sample, a linear correlation was obtained between ultrasound-Doppler flows with thermodilution-1 (0.694) and thermodilution-2 (0.678), [both p<0.001]. When stratified by collateral veins, when no collateral veins were present, there was a significant correlation between Doppler ultrasound with thermodilution-1 (0.698) and thermodilution-2 (0.696) [both p<0.001)]; whereas the correlation was non-significant when collateral veins were present.Conclusions: There is correlation between vascular access flow measurement obtained by Doppler ultrasound and thermodilution; the presence of collateral veins modifies such relationship. It is necessary to implement vascular access surveillance programs that include different monitoring methods in order to mitigate the effect of collateral veins on vascular access flow determination.

20 May 2025 in Healthcare
Verified
Journal Article
Open access
ELEmilia Ferrer López
Emilia Ferrer López
VLVíctor Cantin Lahoz
Víctor Cantin Lahoz
FCFRANCISCO JAVIER RUBIO CASTAÑEDA
FRANCISCO JAVIER RUBIO CASTAÑEDA
AJAguilón-Leiva Juan José
Aguilón-Leiva Juan José
MMMaría García- Magán
María García- Magán
FUFernando Urcola-Pardo
Fernando Urcola-Pardo
Background/Objectives: Individuals with chronic kidney disease often face significant physical and clinical challenges, such as muscle weakness, fatigue, and reduced cardiorespiratory capacity, that impact their quality of life. Physical activity has emerged as an effective intervention to counteract these effects, with clinical guidelines recommending exercise as a standard treatment for kidney transplant recipients. The aim of this study was to assess pretransplant physical activity levels in a cohort of transplant patients and analyze their relationships with cardiovascular risk factors. Methods: A cross-sectional, analytical, and correlational study was conducted from September 2020 to June 2022 with a sample of 122 kidney transplant recipients assessed before kidney transplantation. Sociodemographic data, anthropometric data, comorbidities, renal replacement therapy types, and clinical and analytical data were collected from the patients’ clinical records. Physical activity was assessed via the International Physical Activity Questionnaire. Results: The average time spent waiting for transplantation was 423 ± 405 days, which was longer (387 ± 524) in the group of those under 65 years than in those over 65 years (194 ± 256) (p = 0.010). The median energy expenditure was 1742 (IQR = 1719) METs. In addition, 15.6% of the participants reported inactivity. Men reported higher physical activity levels (median: 2076 METs/week; IQR: 2037) than women did (median: 1386 METs/week; IQR: 1238). A higher level of physical activity was found in non-dialysis patients, overweight patients, and those with a history of stroke. A significant positive correlation was found between physical activity levels and serum urea. Conclusions: Increased physical activity levels were observed in men and in participants under 65 years of age. Patients with cardiovascular risk factors, such as hypertension, diabetes mellitus, dyslipidemia, overweight and obesity, reported lower activity levels, whereas those with a prior history of cerebrovascular accidents engaged in more physical activity. This study highlights the importance of assessing physical activity and promoting exercise for chronic kidney disease patients awaiting kidney transplantation. Further research is needed to explore the evolution of physical activity in this population and its impact post-transplantation.