Iosafat Pinto

Dr. Iosafat Pinto

orcid
Consultant Orthopaedic Surgeon

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 May 2021 in MUSCULOSKELETAL SURGERY
Verified
Journal Article
Closed access
PDF file
LKLazaros Kostretzis
Lazaros Kostretzis
PKP. Konstantinou
P. Konstantinou
Iosafat PintoIosafat Pinto
Iosafat Pinto
Maged ShahinMaged Shahin
Maged Shahin
KDK. Ditsios
K. Ditsios
PPP. Papadopoulos
P. Papadopoulos

1 January 2017 in Case Reports in Orthopedics
Verified
Journal Article
Open access
PDF file
KDKonstantinos Ditsios
Konstantinos Ditsios
EIEirini Iosifidou
Eirini Iosifidou
LKLazaros Kostretzis
Lazaros Kostretzis
PKPanagiotis Konstantinou
Panagiotis Konstantinou
Iosafat PintoIosafat Pinto
Iosafat Pinto
IHIppokratis Hatzokos
Ippokratis Hatzokos
Infected nonunion of a forearm fracture complicated by a considerable skin‐muscle defect poses a great challenge to orthopaedic surgeons. The treatment strategy comprises eradication of the infection, ensuring bony union and soft tissue coverage along with functional restoration. We report a case of a 23‐year‐old man with an open Gustilo‐Anderson IIIb fracture complicated by infected nonunion after internal fixation. After thorough surgical debridement, a considerable soft tissue defect, extensor muscle loss, and posterior interosseous nerve laceration had to be addressed. He was finally treated with bone transportation and bone lengthening followed by tendon transfers.

7 October 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
Iosafat PintoIosafat Pinto
Iosafat Pinto
PKPanagiotis Konstantinou
Panagiotis Konstantinou
LKLazaros Kostretzis
Lazaros Kostretzis
TDTryfon Ditsios
Tryfon Ditsios
CCChrysanthos K Chrysanthou
Chrysanthos K Chrysanthou
KDKonstantinos Ditsios
Konstantinos Ditsios
Background: Depression has been identified as an important determinant of outcomes in hip and knee arthroplasty, but its impact on total ankle arthroplasty (TAA) remains unclear. Given the growing use of TAA as a treatment for end-stage ankle arthritis, understanding psychosocial risk factors is critical for optimizing surgical outcomes. This study aims to assess the effect of preoperative depression on clinical and functional outcomes following total ankle arthroplasty. Methods: A systematic review was conducted in accordance with PRISMA guidelines and prospectively registered with the Open Science Framework. PubMed, Cochrane Library, and CINAHL were searched through August 2025 for studies reporting outcomes of TAA stratified by depression status. Eligible designs included randomized trials, cohort studies and case series. Risk of bias was assessed using the Newcastle–Ottawa Scale (NOS). Given heterogeneity in study designs, depression definitions, and outcome measures, findings were synthesized narratively and summarized using a revised effect-direction plot. Results: Six unique studies involving approximately 9000 patients met inclusion criteria. Five studies were rated as good quality on the Newcastle–Ottawa Scale, while one study was judged to be of moderate quality. Four studies assessing pain outcomes consistently demonstrated worse postoperative pain or less improvement in patients with depression. Three of five studies assessing functional or disability outcomes reported reduced improvement, while two studies found no independent association. Two studies evaluating complications showed higher risks of adverse events, including prolonged hospital stay, non-home discharge, osteophytosis, and implant subsidence, among depressed patients. Revised effect-direction synthesis confirmed a consistent trend toward poorer outcomes across pain, function, and complication domains. Conclusions: Depression is associated with worse pain and higher complication rates following TAA, while its influence on functional recovery was not demonstrated uniformly. These findings support the importance of routine preoperative screening and targeted management of depression. Further prospective, multicenter studies and interventional trials are needed to clarify causality and optimize perioperative care.

17 July 2016 in Case Reports in Orthopedics
Verified
Journal Article
Open access
PDF file
KDKonstantinos Ditsios
Konstantinos Ditsios
NPNikolaos Papadakis
Nikolaos Papadakis
ITIoannis Theodoroudis
Ioannis Theodoroudis
LKLazaros Kostretzis
Lazaros Kostretzis
PKPanagiotis Konstantinou
Panagiotis Konstantinou
ACAnastasios Christodoulou
Anastasios Christodoulou
Osteoid osteoma is a benign bone tumor that appears most frequently in young patients. It is more common in males and it concerns mostly the long bones of the lower limb. A 20-year-old young woman presented to our outpatient department with pain in her left elbow. The symptoms began four years ago. At first, her symptoms were attributed to ulnar neuritis, confirmed by nerve conduction studies. In the following two years, she had undergone two surgical operations for decompression of the ulnar nerve. As a result, she reported poor results, which forced her to take frequently anti-inflammatory drugs for some years. When the patient presented to us, we planned a three-phase bone scan and an elbow MRI, which revealed the lesion. Based on the image findings of osteoid osteoma, we proceeded to the surgical removal of the tumor. Since then, the patient is pain-free and has a full range of motion of the affected elbow. Osteoid osteoma usually mimics multiple pathologies in the upper limb especially joint disease posing a challenge for the physician. The diagnosis requires high index of suspicion and a prompt diagnostic and surgical management.

1 September 2022 in Acta Orthopaedica Belgica
Verified
Journal Article
Closed access
Iosafat PintoIosafat Pinto
Iosafat Pinto
NPNikolaos Patsiogiannis
Nikolaos Patsiogiannis
AKAntonios M. Koumpias
Antonios M. Koumpias
DLDavid Limb
David Limb
PGPeter Giannoudis
Peter Giannoudis
Our aim was to systematically review literature of trauma related rotator cuff tears in order to evaluate the outcome and healing integrity in relation to time of surgery. Our research question was whether earlier surgical repair leads to superior functional results. This review was conducted according to PRISMA statement. A literature search of Pubmed, Embase, Cohrane was conducted, with two researchers assessing studies for eligibility and quality. A total of 20 studies, published between 1980 and 2019, met the inclusion criteria and were divided into two groups based on duration of symptoms before surgery. Group A comprised of studies in which duration was < 3 months and Group B > 3 months. Within each group there was a statistically significant improvement in the CS from pre-operative to post-operative outcome, but the improvement for Group A was statistically higher in comparison to Group B (P=0.01). Nevertheless, there was no significant difference in the final outcome for the two groups (P=0.29). The re-tear rate per 100 patients was calculated 28.5(+/- 7.2) for Group A, and 17.2 (+/- 12.56) for Group B (P=0.056). Our results suggest that functional outcome and tendon healing may not be valid arguments for early surgical repair. Therefore, repair of traumatic RCTs could be recommended whenever technically possible.

5 September 2019 in Journal of Hand Surgery (European Volume)
Verified
Journal Article
Closed access
PDF file
KDKonstantinos Ditsios
Konstantinos Ditsios
LKLazaros Kostretzis
Lazaros Kostretzis
Iosafat PintoIosafat Pinto
Iosafat Pinto