Chungkwon Yoo

Prof. Dr. Chungkwon Yoo

orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 May 2021 in Scientific Reports
Verified
Journal Article
Open access
PDF file
JPJi-Hye Park
Ji-Hye Park
CYChungkwon Yoo
Chungkwon Yoo
HCHyun Woo Chung
Hyun Woo Chung
YKYong Yeon Kim
Yong Yeon Kim
Prostaglandin (PG) analogues are usually prescribed as a first-line therapy in patients with glaucoma because of its once-daily dosing benefit and effective intraocular pressure (IOP) reduction. However, the mechanism of PG analogues is not completely understood. In this study, we investigated the effect of PG analogues on the anterior scleral thickness (AST) in treatment-naïve eyes with primary open-angle glaucoma using anterior segment optical coherence tomography. The AST was measured at the location of the scleral spur, 1000 μm, and 2000 μm posterior to the scleral spur and was compared before and after using the medications for 3 months and 1 year. Among 54 patients enrolled in this study, 31 patients used prostaglandin analogues and 23 patients used dorzolamide/timolol fixed combination (DTFC) drugs. There was no significant difference in untreated IOP, glaucoma severity, and baseline AST values between the two groups. While there was no significant changes in AST after using the DTFC drugs, the AST at all 3 locations showed a significant reduction in both the nasal and temporal sectors after using PG analogues for 1 year (all, P < 0.05). These findings suggest that the AST reduction after using PG analogues might be related with the increased uveoscleral outflow.

27 September 2018 in Acta Ophthalmologica
Verified
Journal Article
Closed access
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YCYeoun Sook Chun
Yeoun Sook Chun
KSKyung Rim Sung
Kyung Rim Sung
CChan Kee Park
Chan Kee Park
HKHwang Ki Kim
Hwang Ki Kim
CYChungkwon Yoo
Chungkwon Yoo
FSfor the LIGHT (Life Quality of Glaucoma Patients Who Underwent Treatment) study of the Korean Glaucoma Society
for the LIGHT (Life Quality of Glaucoma Patients Who Underwent Treatment) study of the Korean Glaucoma Society

17 January 2019 in Acta Ophthalmologica
Verified
Journal Article
Closed access
PDF file
YCYeoun Sook Chun
Yeoun Sook Chun
KSKyung Rim Sung
Kyung Rim Sung
CChan Kee Park
Chan Kee Park
HKHwang Ki Kim
Hwang Ki Kim
CYChungkwon Yoo
Chungkwon Yoo
TSthe LIGHT (Life Quality of Glaucoma Patients Who Underwent Treatment) study of the Korean Glaucoma Society
the LIGHT (Life Quality of Glaucoma Patients Who Underwent Treatment) study of the Korean Glaucoma Society

1 January 2019 in Optometry and Vision Science
Verified
Journal Article
Closed access
JPJi‐Hye Park
Ji‐Hye Park
CYChungkwon Yoo
Chungkwon Yoo
EYEunjoo Yoo
Eunjoo Yoo
YKYong Yeon Kim
Yong Yeon Kim

1 April 2018 in American Journal of Ophthalmology
Verified
Journal Article
Closed access
KNKun-Hoo Na
Kun-Hoo Na
CYChungkwon Yoo
Chungkwon Yoo
JPJi-Hye Park
Ji-Hye Park
YKYong Yeon Kim
Yong Yeon Kim

16 December 2019 in Scientific Reports
Verified
Journal Article
Open access
PDF file
JPJi-Hye Park
Ji-Hye Park
CYChungkwon Yoo
Chungkwon Yoo
YKYong Yeon Kim
Yong Yeon Kim
Although primary open-angle glaucoma (OAG) generally occurs in older individuals and manifests in eyes with elevated intraocular pressure (IOP), it may also occur in young patients or in eyes with an IOP that always measures within the statistically normal range. Recent advances in optical coherence tomography angiography have enabled noninvasive visualization of the vasculature around the optic disc. In this study, we investigated the clinical features of young Korean patients with OAG and compared the peripapillary vessel density of patients with normal-tension glaucoma (NTG) to those with high-tension glaucoma (HTG). The peripapillary vessel density was reduced in eyes with HTG compared with that in normal subjects (HTG: 23.18 ± 2.06% vs. normal subjects: 24.74 ± 1.88%, P value = 0.013). In contrast, the peripapillary vessel density of eyes with NTG was comparable with that of normal eyes (NTG: 23.98 ± 2.30% vs. normal subjects: 24.74 ± 1.88%, P value = 0.505). These findings suggest that young patients with HTG show greater peripapillary microvascular attenuation than healthy subjects or young patients with NTG, indicating that different levels of the initial untreated IOP may have different effects on the peripapillary vessel density in young patients with OAG.