The objective of this study is to evaluate the impact of EEG biofeedback training under normoxic and normobaric hypoxic conditions on both simple and complex reaction times in judo athletes, and to identify the optimal training frequency and environmental conditions that substantially enhance reaction times in the examined athlete groups. The study comprised 20 male judo athlete members of the Polish national judo team in the middleweight and heavyweight categories. We randomly assigned participants to an experimental group and a control group. We conducted the research over four cycles, varying the frequency of EEG biofeedback sessions and environmental circumstances for both the experimental and control groups. Every research cycle had 15 training sessions. The results showed that the experimental group, following the theta/beta regimen, got significantly faster at complex reactions after a training cycle that included sessions every other day at normal oxygen levels. Following daily training sessions in normoxic circumstances, we noted enhancements in simple reaction speeds. Under normobaric hypoxia conditions, the judo athletes showed deterioration in both simple and complex reaction times. The control group showed no similar changes. Daily EEG training in normoxic settings markedly improved simple reaction time, but EEG-BF training conducted every other day greatly raised complicated reaction time. In contrast, training under normobaric hypoxia settings did not result in enhancements in basic or complicated reaction times following EEG training.

Background: Neurofeedback training (NFT) enhances athletic performance through alpha modulation, but optimal inter-session intervals and individual response variability remain poorly understood. Objective: This is the first randomized controlled trial to systematically compare neurofeedback periodization (2-day vs. 3-day inter-session intervals) on neurophysiological adaptations, strength performance, and retention in elite judo athletes. Methods: Thirty-one national-level judokas completed 15 alpha enhancement sessions in 2-day (n = 12), 3-day (n = 12), or control (n = 7) groups, receiving pseudo-neurofeedback with randomized, non-contingent feedback. Primary outcomes included Frontal Alpha Index changes (ΔFAI; frontal alpha power modulation ratio) and squat performance (35–100% 1RM), with secondary assessment of 48/72 h retention and response phenotypes. Results: Mean ΔFAI was modest (E15G-2d: 0.005 ± 0.205; E15G-3d: 0.052 ± 0.202), with early peak responses followed by stabilization. E15G-3d demonstrated superior retention (90.2 ± 3.4% at 72 h vs. 76.8 ± 4.1% at 48 h; p < 0.001) despite similar peaks. Both training groups showed significant strength improvements versus controls (E15G-2d: 2.37 ± 0.66 reps; E15G-3d: 2.00 ± 0.53 reps), yet neurophysiological-performance correlations were non-significant (p > 0.072), indicating strength adaptations via mechanisms independent of alpha modulation. Three response phenotypes emerged (high: 29.0%, moderate: 51.6%, low: 19.4%), representing the first empirical classification of neurofeedback responsiveness in athletes. Conclusions: Three-day intervals uniquely optimize retention through enhanced consolidation, establishing evidence-based periodization guidelines for elite athletes. The dissociation between neural and performance adaptations challenges traditional neurofeedback theory, while individual heterogeneity necessitates personalized protocols for optimal NFT periodization.

Background: The majority of parotid gland tumors are benign, e.g., pleomorphic adenoma (PA) and Warthin’s tumor (WT). From a biomedical point of view, oxidative stress is of significant importance due to its established association with the initiation and progression of various types of cancer, including parotid gland cancers. This study aimed to assess whether blood prooxidant–antioxidant markers could aid in diagnosing and guiding surgery for recurrent malignancies after parotid tumor treatment. Methods: We examined patients (n = 20) diagnosed with WT (n = 14) and PA (n = 6) using histopathological verification and computed tomography (CT) who qualified for surgical treatment. Blood samples were taken before the surgery and again 10 days later for biochemical analysis. The activities of the antioxidant enzymes (SOD, CAT and GPx), the non-enzymatic antioxidants (GSH and UA) and oxidative stress markers (MDA and TOS) were determined in the blood. The activities of CK and LDH and the concentrations of Cor and TAS were measured in the serum. Hb and Ht were determined in whole blood. Results: The patients’ SOD, CAT, and GPx activities after surgery did not differ significantly from their preoperative levels. However, following surgery, their serum TOS levels were significantly elevated in all the patients compared to baseline. In contrast, the plasma MDA concentrations were markedly reduced after surgery. Similarly, the GSH concentrations showed a significant decrease postoperatively. No significant changes were observed in the CK and LDH activities, TAS concentrations, or levels of Hb, Ht and Cor following surgery. Conclusions: The surgical removal of salivary gland tumors did not result in a reduction in oxidative stress at 10 days after surgery. Therefore, further studies are needed to determine the effectiveness of endogenous defense mechanisms in counteracting the oxidative stress induced by salivary gland tumors.