Chen Chen

Dr. Chen Chen

Department of Electrical & Computer Engineering, University of North Carolina at Charlotte, Charlotte, NC 28223, USA

Research Focus & Metrics

Academic Career Length

41Years (1986-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 August 2023 in ACM Computing Surveys
Verified
Journal Article
Open access
CZCe Zheng
Ce Zheng
WWWenhan Wu
Wenhan Wu
CCChen Chen
Chen Chen
TYTaojiannan Yang
Taojiannan Yang
SZSijie Zhu
Sijie Zhu
MSMubarak Shah
Mubarak Shah
Human pose estimation aims to locate the human body parts and build human body representation (e.g., body skeleton) from input data such as images and videos. It has drawn increasing attention during the past decade and has been utilized in a wide range of applications including human-computer interaction, motion analysis, augmented reality, and virtual reality. Although the recently developed deep learning-based solutions have achieved high performance in human pose estimation, there still remain challenges due to insufficient training data, depth ambiguities, and occlusion. The goal of this survey article is to provide a comprehensive review of recent deep learning-based solutions for both 2D and 3D pose estimation via a systematic analysis and comparison of these solutions based on their input data and inference procedures. More than 260 research papers since 2014 are covered in this survey. Furthermore, 2D and 3D human pose estimation datasets and evaluation metrics are included. Quantitative performance comparisons of the reviewed methods on popular datasets are summarized and discussed. Finally, the challenges involved, applications, and future research directions are concluded. A regularly updated project page is provided: https://github.com/zczcwh/DL-HPE .

1 February 2005 in PLOS Biology
Verified
Journal Article
Open access
PDF file
JYJun Yu
Jun Yu
JWJun Wang
Jun Wang
WLWei Lin
Wei Lin
SLSonggang Li
Songgang Li
HLHeng Li
Heng Li
HYHuanming Yang
Huanming Yang
We report improved whole-genome shotgun sequences for the genomes of indica and japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over the drafts of 2002. Tested against a nonredundant collection of 19,079 full-length cDNAs, 97.7% of the genes are aligned, without fragmentation, to the mapped super-scaffolds of one or the other genome. We introduce a gene identification procedure for plants that does not rely on similarity to known genes to remove erroneous predictions resulting from transposable elements. Using the available EST data to adjust for residual errors in the predictions, the estimated gene count is at least 38,000–40,000. Only 2%–3% of the genes are unique to any one subspecies, comparable to the amount of sequence that might still be missing. Despite this lack of variation in gene content, there is enormous variation in the intergenic regions. At least a quarter of the two sequences could not be aligned, and where they could be aligned, single nucleotide polymorphism (SNP) rates varied from as little as 3.0 SNP/kb in the coding regions to 27.6 SNP/kb in the transposable elements. A more inclusive new approach for analyzing duplication history is introduced here. It reveals an ancient whole-genome duplication, a recent segmental duplication on Chromosomes 11 and 12, and massive ongoing individual gene duplications. We find 18 distinct pairs of duplicated segments that cover 65.7% of the genome; 17 of these pairs date back to a common time before the divergence of the grasses. More important, ongoing individual gene duplications provide a never-ending source of raw material for gene genesis and are major contributors to the differences between members of the grass family.

1 December 2005 in Endocrinology
Verified
Journal Article
Closed access
YHYeon-Hee Hong
Yeon-Hee Hong
YNYukihiko Nishimura
Yukihiko Nishimura
DHDaisuke Hishikawa
Daisuke Hishikawa
HTHiroaki Tsuzuki
Hiroaki Tsuzuki
HMHisae Miyahara
Hisae Miyahara
SSShinichi Sasaki
Shinichi Sasaki
It has recently been discovered that G protein-coupled receptors (GPCR) 41 and 43 are characterized by having the short chain fatty acids acetate and propionate as their ligands. The objective of this study was to investigate the involvement of GPCR41, GPCR43, and their ligands in the process of adipogenesis. We measured the levels of GPCR41 and GPCR43 mRNA in both adipose and other tissues of the mouse. GRP43 mRNA expression was higher in four types of adipose tissue than in other tissues, whereas GPCR41 mRNA was not detected in any adipose tissues. A high level of GPCR43 expression was found in isolated adipocytes, but expression level was very low in stromal-vascular cells. Expression of GPCR43 was up-regulated in adipose tissues of mice fed a high-fat diet compared with those fed a normal-fat diet. GPCR43 mRNA could not be detected in confluent and undifferentiated 3T3-L1 adipocytes; however, the levels rose with time after the initiation of differentiation. GPCR41 expression was not detected in confluent and differentiated adipocytes. Acetate and propionate treatments increased lipids present as multiple droplets in 3T3-L1 adipocytes. Propionate significantly elevated the level of GPCR43 expression during adipose differentiation, with up-regulation of PPAR-γ2. Small interfering RNA mediated a reduction of GPCR43 mRNA in 3T3-L1 cells and blocked the process of adipocyte differentiation. In addition, both acetate and propionate inhibited isoproterenol-induced lipolysis in a dose-dependent manner. We conclude that acetate and propionate short chain fatty acids may have important physiological roles in adipogenesis through GPCR43, but not through GPCR41.

1 October 2019 in Cell Metabolism
Verified
Journal Article
Closed access
JYJing Yuan
Jing Yuan
CCChen Chen
Chen Chen
JCJinghua Cui
Jinghua Cui
JLJing Lu
Jing Lu
CYChao Yan
Chao Yan
DLDi Liu
Di Liu

10 May 2018 in IEEE Transactions on Image Processing
Verified
Journal Article
Closed access
SLShangzhen Luan
Shangzhen Luan
CCChen Chen
Chen Chen
Baochang ZhangBaochang Zhang
Baochang Zhang
JHJungong Han
Jungong Han
JLJianzhuang Liu
Jianzhuang Liu
In steerable filters, a filter of arbitrary orientation can be generated by a linear combination of a set of “basis filters”. Steerable properties dominate the design of the traditional filters e.g., Gabor filters and endow features the capability of handling spatial transformations. However, such properties have not yet been well explored in the deep convolutional neural networks (DCNNs). In this paper, we develop a new deep model, namely Gabor Convolutional Networks (GCNs or Gabor CNNs), with Gabor filters incorporated into DCNNs such that the robustness of learned features against the orientation and scale changes can be reinforced. By manipulating the basic element of DCNNs, i.e., the convolution operator, based on Gabor filters, GCNs can be easily implemented and are readily compatible with any popular deep learning architecture. We carry out extensive experiments to demonstrate the promising performance of our GCNs framework and the results show its superiority in recognizing objects, especially when the scale and rotation changes take place frequently. Moreover, the proposed GCNs have much fewer network parameters to be learned and can effectively reduce the training complexity of the network, leading to a more compact deep learning model while still maintaining a high feature representation capacity. The source code can be found at https://github.com/bczhangbczhang.

20 June 2018 in IEEE Transactions on Geoscience and Remote Sensing
Verified
Journal Article
Closed access
Junjun JiangJunjun Jiang
Junjun Jiang
Jiayi MaJiayi Ma
Jiayi Ma
CCChen Chen
Chen Chen
ZWZhongyuan Wang
Zhongyuan Wang
ZCZhihua Cai
Zhihua Cai
Lizhe WangLizhe Wang
Lizhe Wang
As an unsupervised dimensionality reduction method, the principal component analysis (PCA) has been widely considered as an efficient and effective preprocessing step for hyperspectral image (HSI) processing and analysis tasks. It takes each band as a whole and globally extracts the most representative bands. However, different homogeneous regions correspond to different objects, whose spectral features are diverse. Therefore, it is inappropriate to carry out dimensionality reduction through a unified projection for an entire HSI. In this paper, a simple but very effective superpixelwise PCA (SuperPCA) approach is proposed to learn the intrinsic low-dimensional features of HSIs. In contrast to classical PCA models, the SuperPCA has four main properties: 1) unlike the traditional PCA method based on a whole image, the SuperPCA takes into account the diversity in different homogeneous regions, that is, different regions should have different projections; 2) most of the conventional feature extraction models cannot directly use the spatial information of HSIs, while the SuperPCA is able to incorporate the spatial context information into the unsupervised dimensionality reduction by superpixel segmentation; 3) since the regions obtained by superpixel segmentation have homogeneity, the SuperPCA can extract potential low-dimensional features even under noise; and 4) although the SuperPCA is an unsupervised method, it can achieve a competitive performance when compared with supervised approaches. The resulting features are discriminative, compact, and noise-resistant, leading to an improved HSI classification performance. Experiments on three public data sets demonstrate that the SuperPCA model significantly outperforms the conventional PCA-based dimensionality reduction baselines for HSI classification, and some state-of-the-art feature extraction approaches. The MATLAB source code is available at https://github.com/junjun-jiang/SuperPCA.