Traditional medical practices have emerged as the sum of experiential accumulations from the past to the present and are increasingly used today for the purpose of protection from and treatment of diseases. The therapeutic effects of herbal medicines, which form the basis of traditional medical practices, in the treatment of many diseases, especially cancer, have been known since ancient times. Herbal medicines, since they are obtained from natural sources, are considered reliable and healthy, and recently, the interest in herbal medicines has increased even more. Thymbra capitata (L.) Cav. is a plant that grows in the Mediterranean region, is edible, belongs to the class of medicinal plants and has therapeutic properties against many diseases. T. capitata plant has high antioxidant capacity and antimicrobial properties. In our study, the possible anti-cancer effects of the water extract of T. capitata plant on MCF-7 and SH-SY5Y cancer cell lines were determined by the MTT method. As a result of the experimental data obtained, it was determined that the water extract of T. capitata (plant caused a decrease in the percentage of viability of MCF-7 and SH-SY5Y cancer cells, and thus, the water extract of T. capitata plant had anti-cancer effects on MCF-7 and SH-SY5Y cells.

Familial Mediterranean Fever disease (FMF) is an autosomal recessive genetic disease, as well as a disease that seriously impairs the quality of life, accompanied by the appearance of symptoms such as recurrent high fever, peritonitis and acute synovitis. In FMF disease, a mutation status in the MEFV gene is encountered. The presence of faulty protein synthesis as a result of this mutation mediates the emergence of the disease. It is thought that there may be a condition associated with apoptosis in the pathogenesis of this disease. Apoptosis is a form of cell death in which energy is expended and programmed with great importance in maintaining cellular balance. In this study, the levels of Caspase 3, Caspase 8, Caspase 9, Granzyme B and Apaf 1 from apoptosis-related proteins were analyzed using the ELISA method in serum samples obtained from FMF patients treated with colchicine and a healthy control group. There was no statistically significant difference between Caspase 3 (P=0, 111), Granzyme B (P=0, 304), Apaf 1 (P=0, 097) and Caspase 8 (P=0, 245) levels in the FMF patient group compared to the control group (p >0, 05). A statistically significant difference was found in the Caspase 9 levels in the FMF patient group (P=0.001) compared to the control group (p