A number of dengue viruses can seriously impact public health, and their spread has long been a concern. The development and administration of antiviral drugs have played a crucial role in combating viral infections in recent years. These drugs have shown that they can effectively inhibit viral replication and alleviate associated viral complications. The aim of this article is to provide an overview of current evidence on the effectiveness of administered antiviral drugs in controlling viral replication and treating viral problems. In the present study, the PyRx tool was used to docked proteins and ligands. In summary, the present study shows that rosmarinic acid has remarkable docking values against various dengue viral targets. Specifically, it shows a docking value of −8.0 for DENV1-E111, -8.1 for the RNA-dependent RNA polymerase (NS5), −8.2 for the non-structural A chain protein 1 (NS1), and −8.6 for the RNA helicase. These results suggest that rosmarinic acid may have an antiviral effect against the virus's target proteins. Further research is needed to investigate the therapeutic effects of rosmarinic acid in fighting viral infections. In addition, many enzymatic activities of rosmarinic acid have been reported by the PASS (Prediction of Activity Spectra for Substances) tool. The present investigation led to the definitive conclusion that rosmarinic acid possesses remarkable antiviral properties. The present study is promising for future applications, particularly in the search for a drug molecule that can effectively combat a variety of viral infections.
This review paper examines Climate-Smart Agriculture (CSA) as a crucial approach to mitigate greenhouse gas emissions from India's agriculture sector. It analyzes various CSA practices implemented in India, focusing on their effectiveness in reducing emissions while enhancing food security and farmer livelihoods. The paper explores crop management techniques like improved varieties, nutrient management, and water management, alongside soil management practices such as conservation agriculture and agroforestry. Additionally, it delves into livestock management strategies, including improved feeding practices and manure management. The review highlights the role of government policies and programs in promoting CSA adoption, such as the National Mission for Sustainable Agriculture and the Parampara at Krishi Vikas Yojana. Challenges hindering wider CSA adoption, including financial constraints, lack of awareness, and data gaps, are discussed. The paper concludes by emphasizing the need to address these challenges and leverage opportunities like strengthening extension services, promoting farmer-to-farmer learning, and utilizing technology to unlock the full potential of CSA in India.