Apurva Vashist

Dr. Apurva Vashist


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 August 2024 in INTERNATIONAL JOURNAL OF EXPERIMENTAL RESEARCH AND REVIEW
Verified
Journal Article
Open access
PDF file
AVApurva Vashist
Apurva Vashist
ASAnil Kumar Sagar
Anil Kumar Sagar
AGAnjali Goyal
Anjali Goyal
One of the biggest risks facing women in the twenty-first century is breast cancer. Invasion lobular carcinoma and invasion ductal carcinoma are the two main categories into which it is divided. Omics data is used to identify predictive biomarker signatures for clinical applications to detect breast cancer. Predictive performance has significantly improved because of recent advancements in machine learning techniques. Here, we are using an approach built on symbolic regression called the QLattice on a variety of clinical omics data sets. Through the identification of potential regulatory interactions between biomolecules, this method creates efficient, high-performing models that can forecast and explain the results of a specific omics experiment. The models have the potential to make it easier to find new biomarker signatures due to their clarity and obvious functional shape, which make them simple and easy to comprehend. A comprehensive experimental investigation was conducted to assess the machine learning model's efficacy in terms of the Area under the Curve (AUC) for breast cancer. The outcomes, which were contrasted with other approaches, demonstrate the suggested framework's efficacy and capacity to beat the alternative algorithms in terms of AUC, which is 0.66. Here, we profiled breast tumors in detail, including ductal carcinoma, mixed carcinoma, and invasive lobular carcinoma, by using the Gaussian method and TNXB gene.

1 December 2024 in IAES International Journal of Artificial Intelligence (IJ-AI)
Verified
Journal Article
Open access
PDF file
AVApurva Vashist
Apurva Vashist
ASAnil Kumar Sagar
Anil Kumar Sagar
AGAnjali Goyal
Anjali Goyal
Breast cancer is the most frequent cancer in women and the second-leading cause of cancer-related deaths globally. The main problems in managing breast cancer are high heterogeneity and the formation of therapeutic resistance. White blood cells, omics and large Wisconsin diagnostic breast cancer datasets present the three-decade genomic revolution and advance the understanding of cellular function. The precision of cancer diagnosis has also increased over the past decades. High throughput sequencing, screening, and artificial intelligence technologies have significantly improved and increased the methodologies used for diagnosis, prognosis, and therapy. This paper follows several phases of breast cancer, studies datasets and evaluate many algorithms of machine learning (ML) used for analysis and feature selection i.e. k-means, similarity correlation, genetic algorithm, and principal component analysis, have been used to recognize the subset of proteins with the highest significance for breast cancer prediction by using different biomarkers. The best correlation, as determined by Pearson correlation, between copy number and protein is 0.014, and the accuracy achieved by the genetic algorithm is 93.5% using multi-omics datasets.

11 October 2023
Verified
Book Chapter
Closed access
PDF file
AVApurva Vashist
Apurva Vashist
ASAnil Kumar Sagar
Anil Kumar Sagar
AGAnjali Goyal
Anjali Goyal

1 January 2023 in JIMS8I International Journal of Information Communication and Computing Technology
Verified
Journal Article
Closed access
PDF file
AVApurva Vashist
Apurva Vashist
Big data analytics may be used in future smart cities to better understand how residents use the area. Transportation companies may be better able to assess the quality of their services if they have a greater grasp of consumers' travel habits. The triangulation of mobile phone data from millions of anonymous users has made it possible to forecast frequent drivers. Surveys conducted locally and nationally could show how useful the paradigm is it is possible to incorporate data from smart carts, metro and bus vehicle positions, and other sources to estimate how long it takes for passengers to board and deboard trains. In this paper, the Delphi method to compare modern metropolises to forthcoming smart cities. The estimate-talk-estimate approach (ETE), also referred to as the Delphi methodology, is a methodical and qualitative way of forecasting that involves asking a series of questions of experts to elicit their perspectives. The research methodology presents an evaluation and model performance by using deep learning algorithms.


1 January 2024 in JIMS8I International Journal of Information Communication and Computing Technology
Verified
Journal Article
Closed access
PDF file
TNTanishq Negi
Tanishq Negi
AVApurva Vashist
Apurva Vashist
This research delves into the fusion of machine learning (ML) and deep learning (DL) methodologies for the early detection of glaucoma, acknowledging its status as the primary cause of irreversible blindness. Through the utilization of diverse imaging modalities such as optical coherence tomography (OCT) scans and fundus photographs, these algorithms demonstrate proficiency in identifying crucial features indicative of glaucomatous changes. The paper evaluates techniques including support vector machines, random forests, and convolutional neural networks, emphasizing their effectiveness in analyzing data pertaining to the eye. Additionally, it addresses challenges such as class imbalance and data heterogeneity, emphasizing the importance of extensive datasets and transfer learning. Ultimately, the study underscores the necessity of early glaucoma detection and explores the potential of ML and DL techniques in achieving this aim.