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Increasing the effectiveness of known, well-tested drugs is a promising low-cost alternative to the search for new drug molecular forms. Powerful approaches to solve this problem are (a) an active drug particle size reduction down to the nanoscale and (b) thermodynamically metastable but kinetically stable crystal modifications of drug acquisition. The combined cryochemical method has been used for size and structural modifications of the antibacterial drug 2,3-quinoxalinedimethanol-1,4-dioxide (dioxidine). The main stage of the proposed technique includes the formation of a molecular vapor of the drug substance, combined with a carrier gas (CO2) flow, followed by a fast condensation of the drug substance and CO2 molecules on a cooled-by-liquid nitrogen surface of preparative cryostate. It was established that the molecular chemical structure of the drug substance remained unchanged during cryochemical modification; however, it led to a significant decrease of the drug particles’ size down to nanosizes and changes in the crystal structures of the solid drug nanoforms obtained. Varying carrier gas (CO2) flow led to changes in their solid phase composition. A higher dissolution rate and changes in antibacterial activity were demonstrated for cryomodified dioxidine samples in comparison to the properties of the initial pharmacopeia dioxidine.
Tatyana Shabatina; Yurii Morosov; Andrey Soloviev; Andrey Shabatin; Olga Vernaya; Michail Melnikov. Cryochemical Production of Drug Nanoforms: Particle Size and Crystal Phase Control of the Antibacterial Medication 2,3-Quinoxalinedimethanol-1,4-dioxide (Dioxidine). Nanomaterials 2021, 11, 1588 .
AMA StyleTatyana Shabatina, Yurii Morosov, Andrey Soloviev, Andrey Shabatin, Olga Vernaya, Michail Melnikov. Cryochemical Production of Drug Nanoforms: Particle Size and Crystal Phase Control of the Antibacterial Medication 2,3-Quinoxalinedimethanol-1,4-dioxide (Dioxidine). Nanomaterials. 2021; 11 (6):1588.
Chicago/Turabian StyleTatyana Shabatina; Yurii Morosov; Andrey Soloviev; Andrey Shabatin; Olga Vernaya; Michail Melnikov. 2021. "Cryochemical Production of Drug Nanoforms: Particle Size and Crystal Phase Control of the Antibacterial Medication 2,3-Quinoxalinedimethanol-1,4-dioxide (Dioxidine)." Nanomaterials 11, no. 6: 1588.
The presented chapter is devoted to chiral biosensing using various metal nanostructures and their hybrid nanosystems with optically active bio- and organic molecules. Plasmonic nanosystems and nanostructures provide an excellent platform for label-free detection of molecular adsorption by detecting tiny changes in the local refractive index or amplification of light-induced processes in biomolecules. Based on recent theoretical and experimental developments in plasmon-enhanced local electric fields, we consider the main types of molecular-plasmonic hybrid systems capable of generating an amplified chiroptical signal for such applications as detecting the presence of certain biomolecules and (in some cases) determination of their orientation and higher-order structure.
Vladimir E. Bochenkov; Tatyana I. Shabatina. Chiral Hybrid Nanosystems and Their Biosensing Applications. Smart Nanosystems for Biomedicine, Optoelectronics and Catalysis 2020, 1 .
AMA StyleVladimir E. Bochenkov, Tatyana I. Shabatina. Chiral Hybrid Nanosystems and Their Biosensing Applications. Smart Nanosystems for Biomedicine, Optoelectronics and Catalysis. 2020; ():1.
Chicago/Turabian StyleVladimir E. Bochenkov; Tatyana I. Shabatina. 2020. "Chiral Hybrid Nanosystems and Their Biosensing Applications." Smart Nanosystems for Biomedicine, Optoelectronics and Catalysis , no. : 1.
The presented paper is a review article discussing existing synthesis methods and different applications of nanosized magnetic nanoparticles. It was shown that, in addition to the spectrum of properties typical for nanomaterials (primarily a large specific surface area and a high fraction of surface atoms), magnetic nanoparticles also possess superparamagnetic properties that contribute to their formation of an important class of biomedical functional nanomaterials. This primarily concerns iron oxides magnetite and maghemite, for which in vitro and in vivo studies have shown low toxicity and high biocompatibility in comparison with other magnetic nanomaterials. Due to their exceptional chemical, biological, and physical properties, they are widely used in various areas, such as magnetic hyperthermia, targeted drug delivery, tissue engineering, magnetic separation of biological objects (cells, bacteria, viruses, DNA, and proteins), and magnetic diagnostics (they are used as agents for MRS and immunoassay). In addition to discussing the main problems and prospects of using nanoparticles of magnetic iron oxides for advanced biomedical applications, information is also reflected on their structure, production methods, and properties.
Tatyana I. Shabatina; Olga I. Vernaya; Vladimir P. Shabatin; Mikhail Ya. Melnikov. Magnetic Nanoparticles for Biomedical Purposes: Modern Trends and Prospects. Magnetochemistry 2020, 6, 30 .
AMA StyleTatyana I. Shabatina, Olga I. Vernaya, Vladimir P. Shabatin, Mikhail Ya. Melnikov. Magnetic Nanoparticles for Biomedical Purposes: Modern Trends and Prospects. Magnetochemistry. 2020; 6 (3):30.
Chicago/Turabian StyleTatyana I. Shabatina; Olga I. Vernaya; Vladimir P. Shabatin; Mikhail Ya. Melnikov. 2020. "Magnetic Nanoparticles for Biomedical Purposes: Modern Trends and Prospects." Magnetochemistry 6, no. 3: 30.
The paper reviews the results of the authors on the production of hybrid nanosystems based on liquid crystalline (LC) long-chain cyano(alkyl and alkoxy)biphenyls (5CB, 5OCB, and 8CCB) including nanosized metal species. The samples were obtained through the direct incorporation of metal (silver and copper) atoms and small clusters into mesogenic CB matrices via a low temperature co-condensation technique, and the formation of biligand metal complexes were revealed by FTIR and ESR-spectroscopy. The heating of the systems led to the controlled growth of metal clusters and nanosized metal particles of the definite size beginning from 1 up to 200 nanometers, and their highly-ordered assemblies stabilized in the solid and liquid crystalline phases. It is shown that supramolecular ordering in different LC phases of cyanobiphenyl matrices determines the size and shape of nanosized metal species that are formed in the systems under investigation, as well as the morphology of their aggregates. TEM and atomic force microscopy (AFM) data revealed the existence of orientationally-ordered nanostructures in the nematic phases of 5CB and 5OCB. The growth of quasi-fractal 2D-aggregates was shown for layer-structured smectic mesophase of 8CB. The UV–Visible spectra of hybrid metal–mesogenic nanosystems Ag-5CB and Cu-5CB that were incorporated into polymeric films revealed intensive plasmonic bands at 400–450 nm, similar to silver nanoparticles, and 540–650 nm, similar to copper nanoparticles. The increasing of the metal contents in the samples caused the growth of highly anisometric shaped metal rods, with the ratio of the length to the diameter being more than 10 and plasmonic bands at region of λ ≥ 650 nm.
Tatyana I. Shabatina; Yurii N. Morosov. Hybrid Nanosystems Based on Metal-Containing Mesogenic CyanoAlkyl and Alkoxybiphenyls. Crystals 2020, 10, 77 .
AMA StyleTatyana I. Shabatina, Yurii N. Morosov. Hybrid Nanosystems Based on Metal-Containing Mesogenic CyanoAlkyl and Alkoxybiphenyls. Crystals. 2020; 10 (2):77.
Chicago/Turabian StyleTatyana I. Shabatina; Yurii N. Morosov. 2020. "Hybrid Nanosystems Based on Metal-Containing Mesogenic CyanoAlkyl and Alkoxybiphenyls." Crystals 10, no. 2: 77.
New hybrid nanosystems containing the antibacterial substances dioxidine or gentamicin sulfate with bioactive metal (Ag, Cu) nanoparticles have been obtained by a cryogenic freeze-drying method and incorporate further the nanocomposites thus obtained into the cryogenically structured biopolymeric matrices based on gelatin, calcium alginate, and chitosan. FTIR, UV-visible, and NMR spectroscopy, TEM and SEM microscopy data show that the resulting systems consist of wide-porous polymer sponges (pore diameters, 10–200 μm) that contain antibacterial drugs and silver (2–30 nm) or copper (1–5 nm) nanoparticles. The investigation showed that these systems ensure a gradual release of dioxidine (from 40 min up to 3 days), depending on the nature of the matrix and its microstructure. The higher activity of hybrid composites based on nanometals and dioxidine or incorporated into cryostructured biopolymer matrices against the bacterial strains of Escherichia coli 52, Staphylococcus aureus 144 is demonstrated as compared to the individual components in the same matrices.
Tatyana I. Shabatina; Olga I. Vernaya; Vladimir P. Shabatin; Michail Y. Melnikov; Alexandr M. Semenov; Vladimir I. Lozinsky. Metal Nanoparticle Containing Nanocomposites of Drug Substances and Their Potential Biomedical Applications. Applied Sciences 2019, 10, 170 .
AMA StyleTatyana I. Shabatina, Olga I. Vernaya, Vladimir P. Shabatin, Michail Y. Melnikov, Alexandr M. Semenov, Vladimir I. Lozinsky. Metal Nanoparticle Containing Nanocomposites of Drug Substances and Their Potential Biomedical Applications. Applied Sciences. 2019; 10 (1):170.
Chicago/Turabian StyleTatyana I. Shabatina; Olga I. Vernaya; Vladimir P. Shabatin; Michail Y. Melnikov; Alexandr M. Semenov; Vladimir I. Lozinsky. 2019. "Metal Nanoparticle Containing Nanocomposites of Drug Substances and Their Potential Biomedical Applications." Applied Sciences 10, no. 1: 170.
This chapter reviews the methods of supramolecular chemistry and cryochemistry to study the formation, morphological and structural properties, and possible applications of hybrid nanostructures and nanosized aggregates comprising plasmonic metals (silver and copper) and several mesogenic compounds, which exhibit different liquid crystalline mesophases—nematics, smectics, and cholesterics. Low-temperature vacuum co-condensation of reagent vapors on cooled surfaces of quartz, KBr, CaF2, or polished copper was used to synthesize hybrid nanosystems including silver and copper and long-chain mesogenic derivatives of alkylcyanobiphenyls under molecular beam conditions. Controlled thermal treatment of the samples allowed the directed formation of metal nanoparticles of definite size from 2 up to 100 nm. It was shown that the procedures of temperature treatments and molecular self-organization of different liquid crystalline phases controlled the size and morphology of nanoparticles and their aggregates, which were formed in the system. Transmission electron microscopy (TEM) and atomic force microscopy (AFM) data of the samples show the formation of orientationally ordered structures in nematic mesophases. Formation of flat 2D aggregates was found in layered smectic mesophases. Optical absorbance spectra of silver/4-pentyl-4-cyanobiphenyl (Ag/5СВ) and copper/4-pentyl-4-cyanobiphenyl (Cu/5CB) samples encapsulated in polymer poly-para-xylylene at 300 K contained characteristic bands of plasmonic absorbance of metal nanoparticles at 420–440 nm and 560–600 nm. Rising metal concentration in the sample led to the performable growth of rod-like metal particles with anisometric ratio l/d > 20 and intensive absorbance at higher wavelengths (λ ≥ 650 nm). New hybrid nanosystems based on biomolecules of cholesterol or its heteroatomic analog thiocholesterol including nanosized silver particles of d = 5.0 ± 0.5 and d = 2.5 ± 0.5 nm, respectively, were obtained. Highly ordered 1D-, 2D-, and 3D structures containing silver nanoparticles were formed from concentrated organic sols at different support surfaces by removing the inert solvent from triple metal/ligand/solvent system and by cooling the binary metal/ligand system from isotropic state to the cholesteric liquid crystalline mesophase. The microstructure and composition of the hybrid nanosystems were characterized by FTIR, UV-Vis spectroscopy, TEM, and selected area electron diffraction (SAED). It was shown that hybrid nanosystems based on silver nanoparticles covered by a stabilizing layer of mesogenic molecules of thiocholesterol display selectivity in adsorption of optical isomers of the selected compounds.
Tatyana I. Shabatina. Self-Assembled Nanostructures Formation in Hybrid Metal-Mesogenic Systems. Nanostructures in Energy Generation, Transmission and Storage 2019, 1 .
AMA StyleTatyana I. Shabatina. Self-Assembled Nanostructures Formation in Hybrid Metal-Mesogenic Systems. Nanostructures in Energy Generation, Transmission and Storage. 2019; ():1.
Chicago/Turabian StyleTatyana I. Shabatina. 2019. "Self-Assembled Nanostructures Formation in Hybrid Metal-Mesogenic Systems." Nanostructures in Energy Generation, Transmission and Storage , no. : 1.
Biosensing requires fast, selective, and highly sensitive real-time detection of biomolecules using efficient simple-to-use techniques. Due to a unique capability to focus light at nanoscale, plasmonic nanostructures provide an excellent platform for label-free detection of molecular adsorption by sensing tiny changes in the local refractive index or by enhancing the light-induced processes in adjacent biomolecules. This review discusses the opportunities provided by surface plasmon resonance in probing the chirality of biomolecules as well as their conformations and orientations. Various types of chiral plasmonic nanostructures and the most recent developments in the field of chiral plasmonics related to biosensing are considered.
Vladimir E. Bochenkov; Tatyana I. Shabatina. Chiral Plasmonic Biosensors. Biosensors 2018, 8, 120 .
AMA StyleVladimir E. Bochenkov, Tatyana I. Shabatina. Chiral Plasmonic Biosensors. Biosensors. 2018; 8 (4):120.
Chicago/Turabian StyleVladimir E. Bochenkov; Tatyana I. Shabatina. 2018. "Chiral Plasmonic Biosensors." Biosensors 8, no. 4: 120.
Magnetite nanoparticles 2–20 nm in size, forming agglomerates up to 70 nm in size, are obtained by cryochemical synthesis.
O. I. Vernaya; V. P. Shabatin; T. I. Shabatina. Cryochemical Synthesis of Magnetite Nanoparticles. Moscow University Chemistry Bulletin 2018, 73, 257 -259.
AMA StyleO. I. Vernaya, V. P. Shabatin, T. I. Shabatina. Cryochemical Synthesis of Magnetite Nanoparticles. Moscow University Chemistry Bulletin. 2018; 73 (5):257-259.
Chicago/Turabian StyleO. I. Vernaya; V. P. Shabatin; T. I. Shabatina. 2018. "Cryochemical Synthesis of Magnetite Nanoparticles." Moscow University Chemistry Bulletin 73, no. 5: 257-259.
The structures of small silver clusters (Ag2, Ag3, Ag13) and their interaction with ligands of the cholesterol series, namely, cholesterol (Ch) and thiocholesterol (TCh), are calculated by the density functional theory (DFT) methods and the second-order Møller–Plesset perturbation theory (MP2). Trends in the geometric structure and interaction energy of the silver–cholesterol ligand cluster are estimated depending on the size of the metal cluster and the replacement of cholesterol by the sulfur-containing analogue. For Ch–Ag13 and TCh–Ag13 systems, the geometric structure of the metallic subsystem is a slightly distorted icosahedron with the Ag–Ag bond length ranged 2.8–3.0 Å. Cholesterol is coordinated to the icosahedral facet so that the shortest Ag–O distances range from 2.3 to 2.4 Å. In the case of thiocholesterol, a configuration in which the ligand is coordinated by the edge of the icosahedron with two approximately equal distances of Ag–S (2.537 and 2.547 Å) is preferable.
A. Yu. Ermilov; E. S. Lukyanova; Ya. A. Gromova; T. I. Shabatina. Interaction of Silver Clusters with Cholesterol Ligands. Moscow University Chemistry Bulletin 2018, 73, 251 -256.
AMA StyleA. Yu. Ermilov, E. S. Lukyanova, Ya. A. Gromova, T. I. Shabatina. Interaction of Silver Clusters with Cholesterol Ligands. Moscow University Chemistry Bulletin. 2018; 73 (5):251-256.
Chicago/Turabian StyleA. Yu. Ermilov; E. S. Lukyanova; Ya. A. Gromova; T. I. Shabatina. 2018. "Interaction of Silver Clusters with Cholesterol Ligands." Moscow University Chemistry Bulletin 73, no. 5: 251-256.
Nanoforms of the antimicrobial drug substance 2,3-bis-(hydroxymethyl) quinoxaline-N,N′-dioxide with particles sizes between 50 and 300 nm were obtained by cryochemical modification of the initial pharmaceutical substance using a freeze-drying technique and were characterized by different physicochemical methods (FTIR, UV-Vis, 1H-NMR, DSC, TG and X-ray diffraction) and transmission electron microscopy (TEM). The data obtained from FTIR- and UV–Vis-spectroscopy confirmed the unaltered chemical structure of dioxidine molecules due to the cryochemical modification method. At the same time, X-ray diffraction and thermal analysis data show the change of the crystal structure compared to the parameters of the initial pharmaceutical dioxidine substance. A higher dissolution rate was revealed for cryomodified dioxidine nanoforms. The existence of three polymorphic crystal phases was established for cryomodified dioxidine samples possessed by some thermal activation processes: two anhydrous polymorphic phases, triclinic (T) and monoclinic (M), and one hydrated form (H).
Tatyana I. Shabatina; Olga I. Vernaya; Vladimir P. Shabatin; Iuliia V. Evseeva; Michail Ya Melnikov; Andrew N. Fitch; Vladimir V. Chernyshev. Cryochemically Obtained Nanoforms of Antimicrobial Drug Substance Dioxidine and Their Physico-chemical and Structural Properties. Crystals 2018, 8, 298 .
AMA StyleTatyana I. Shabatina, Olga I. Vernaya, Vladimir P. Shabatin, Iuliia V. Evseeva, Michail Ya Melnikov, Andrew N. Fitch, Vladimir V. Chernyshev. Cryochemically Obtained Nanoforms of Antimicrobial Drug Substance Dioxidine and Their Physico-chemical and Structural Properties. Crystals. 2018; 8 (7):298.
Chicago/Turabian StyleTatyana I. Shabatina; Olga I. Vernaya; Vladimir P. Shabatin; Iuliia V. Evseeva; Michail Ya Melnikov; Andrew N. Fitch; Vladimir V. Chernyshev. 2018. "Cryochemically Obtained Nanoforms of Antimicrobial Drug Substance Dioxidine and Their Physico-chemical and Structural Properties." Crystals 8, no. 7: 298.
Hybrid nanocomposites consisting of an antibacterial drug, dioxidine, and copper nanoparticles are obtained by cryochemical synthesis. It is shown by UV spectroscopy, X-ray diffraction, PAM, and low temperature argon adsorption that the obtained hybrid systems represent dioxidine particles with a size of 100 to 400 nm, including copper particles with the size of 50 to 150 nm. The resulting composites possessed higher antibacterial activity against E. coli 52 than the initial dioxidine and copper nanoparticles.
O. I. Vernaya; D. I. Khvatov; A. V. Nuzhdina; V. V. Fedorov; V. P. Shabatin; A. M. Semenov; T. I. Shabatina. Cu/dioxidine hybrid nanocomposites: cryochemical synthesis and antibacterial activity. Moscow University Chemistry Bulletin 2017, 72, 224 -226.
AMA StyleO. I. Vernaya, D. I. Khvatov, A. V. Nuzhdina, V. V. Fedorov, V. P. Shabatin, A. M. Semenov, T. I. Shabatina. Cu/dioxidine hybrid nanocomposites: cryochemical synthesis and antibacterial activity. Moscow University Chemistry Bulletin. 2017; 72 (5):224-226.
Chicago/Turabian StyleO. I. Vernaya; D. I. Khvatov; A. V. Nuzhdina; V. V. Fedorov; V. P. Shabatin; A. M. Semenov; T. I. Shabatina. 2017. "Cu/dioxidine hybrid nanocomposites: cryochemical synthesis and antibacterial activity." Moscow University Chemistry Bulletin 72, no. 5: 224-226.
Dynamic sublimation in a stream of heated carrier gas and low-temperature condensation are used to perform structural and dimensional modification of nonsteroidal anti-inflammatory preparation of 4-hydroxy-2-methyl-N-(2-pyridinyl)-2Н-1,2-benzothiazin-3-carboxamide 1,1-dioxide (piroxicam) and to obtain its nanoscale form. Thus obtained samples correspond to the known thermodynamically metastable Form III of the compound. The average particle size of the preparation is d av = 300 ± 30 nm. The resulting nanosized form of piroxicam is relatively stable with respect to structural and dimensional transformations for at least four years.
Yu. N. Morozov; V. V. Fedorov; V. P. Shabatin; O. I. Vernaya; V. V. Chernyshev; A. S. Abel; I. V. Arhangel’Skii; T. I. Shabatina; G. B. Sergeev. Cryochemical modification of drugs: Nanosized form III piroxicam and its physical and chemical properties. Moscow University Chemistry Bulletin 2016, 71, 287 -294.
AMA StyleYu. N. Morozov, V. V. Fedorov, V. P. Shabatin, O. I. Vernaya, V. V. Chernyshev, A. S. Abel, I. V. Arhangel’Skii, T. I. Shabatina, G. B. Sergeev. Cryochemical modification of drugs: Nanosized form III piroxicam and its physical and chemical properties. Moscow University Chemistry Bulletin. 2016; 71 (5):287-294.
Chicago/Turabian StyleYu. N. Morozov; V. V. Fedorov; V. P. Shabatin; O. I. Vernaya; V. V. Chernyshev; A. S. Abel; I. V. Arhangel’Skii; T. I. Shabatina; G. B. Sergeev. 2016. "Cryochemical modification of drugs: Nanosized form III piroxicam and its physical and chemical properties." Moscow University Chemistry Bulletin 71, no. 5: 287-294.
One way to increase bioavailability and efficiency of drug substances is to decrease their particles up to nanoscale level and to change their crystal structure. A new stable nanoscale form of a polymorphic antibacterial 2,3-bis-(hydroxymethyl)-quinoxaline-N,N′-dioxyde (dioxidine) modification characterized with a gas chromatography, NMR, XRF, TEM, and thermoanalytic methods (TG, DTG, DSC) was obtained via cryochemical synthesis. The new polymorphic dioxidine modification was proved to be more active in growth inhibition processes of gram-positive M. cyaneum 98 and gram-negative E. coli bacterial strains than officinal modification.
O. I. Vernaya; V. P. Shabatin; A. M. Semenov; T. I. Shabatina. Obtaining ultradispersed dioxidine powder modified via cryochemical synthesis and determining its antibacterial activity. Moscow University Chemistry Bulletin 2016, 71, 295 -298.
AMA StyleO. I. Vernaya, V. P. Shabatin, A. M. Semenov, T. I. Shabatina. Obtaining ultradispersed dioxidine powder modified via cryochemical synthesis and determining its antibacterial activity. Moscow University Chemistry Bulletin. 2016; 71 (5):295-298.
Chicago/Turabian StyleO. I. Vernaya; V. P. Shabatin; A. M. Semenov; T. I. Shabatina. 2016. "Obtaining ultradispersed dioxidine powder modified via cryochemical synthesis and determining its antibacterial activity." Moscow University Chemistry Bulletin 71, no. 5: 295-298.
Ya. A. Gromova; E. S. Anistratova; T. I. Shabatina; N. B. Rozhmanova; E. N. Shapovalova; O. A. Shpigun. Production of chiral matrices with hybrid silver–thiocholesterol nanosystems and study of their properties. Moscow University Chemistry Bulletin 2016, 71, 16 -20.
AMA StyleYa. A. Gromova, E. S. Anistratova, T. I. Shabatina, N. B. Rozhmanova, E. N. Shapovalova, O. A. Shpigun. Production of chiral matrices with hybrid silver–thiocholesterol nanosystems and study of their properties. Moscow University Chemistry Bulletin. 2016; 71 (1):16-20.
Chicago/Turabian StyleYa. A. Gromova; E. S. Anistratova; T. I. Shabatina; N. B. Rozhmanova; E. N. Shapovalova; O. A. Shpigun. 2016. "Production of chiral matrices with hybrid silver–thiocholesterol nanosystems and study of their properties." Moscow University Chemistry Bulletin 71, no. 1: 16-20.
T. I. Shabatina; A. A. Belyaev; Yu. N. Morosov. Molecular Organisation and Phase-Structural States of Hybrid Metal-Mesogenic Nanosystems Based on Alkylcyanobiphenyls and their Optical Properties. Liquid Crystals and their Application 2015, 15, 40 -47.
AMA StyleT. I. Shabatina, A. A. Belyaev, Yu. N. Morosov. Molecular Organisation and Phase-Structural States of Hybrid Metal-Mesogenic Nanosystems Based on Alkylcyanobiphenyls and their Optical Properties. Liquid Crystals and their Application. 2015; 15 (4):40-47.
Chicago/Turabian StyleT. I. Shabatina; A. A. Belyaev; Yu. N. Morosov. 2015. "Molecular Organisation and Phase-Structural States of Hybrid Metal-Mesogenic Nanosystems Based on Alkylcyanobiphenyls and their Optical Properties." Liquid Crystals and their Application 15, no. 4: 40-47.
New hybrid nanosystems based on biomolecules of cholesterol and its heteroatomic analog thiocholesterol including nanosized silver particles of d = 5.0 ± 0.5 and d = 2.5 ± 0.5 nm, correspondingly, have been obtained by two-phase chemical synthesis. Ordered 1D, 2D, and 3D structures including silver nanoparticles were formed on different support surfaces by removing of inert solvent from triple metal/ligand/solvent system and by cooling of binary metal/ligand system from isotropic state to liquid crystalline mesophase. The microstructure and composition of the hybrid nanosystems were characterized by Fourier transform infrared spectroscopy, UV–vis spectroscopy, and transmission electron microscopy.
Tatyana I. Shabatina; Anatolii A. Belyaev; Gleb B. Sergeev. Self-Assembled Nanostructures in Silver–Cholesterol and Silver–Thiocholesterol Systems. BioNanoScience 2013, 3, 289 -294.
AMA StyleTatyana I. Shabatina, Anatolii A. Belyaev, Gleb B. Sergeev. Self-Assembled Nanostructures in Silver–Cholesterol and Silver–Thiocholesterol Systems. BioNanoScience. 2013; 3 (3):289-294.
Chicago/Turabian StyleTatyana I. Shabatina; Anatolii A. Belyaev; Gleb B. Sergeev. 2013. "Self-Assembled Nanostructures in Silver–Cholesterol and Silver–Thiocholesterol Systems." BioNanoScience 3, no. 3: 289-294.
Linear aggregates including nanosized silver particles (d = 2.5 ± 0.5 nm) stabilized in a cholesteric mesophase of thiocholesterol forming by cooling from the isotropic state are obtained. The composition and the structure of the aggregates are determined by FTIR, UV-Vis spectroscopy, transmission electron microscopy, and electronic diffraction. The optical properties of the silver-thiocholesterol and silver-thiocholesterol-toluene systems are studied.
A. A. Belyaev; T. I. Shabatina; G. B. Sergeev. Nanosized silver/thiocholesterol aggregates. Moscow University Chemistry Bulletin 2009, 64, 182 -185.
AMA StyleA. A. Belyaev, T. I. Shabatina, G. B. Sergeev. Nanosized silver/thiocholesterol aggregates. Moscow University Chemistry Bulletin. 2009; 64 (4):182-185.
Chicago/Turabian StyleA. A. Belyaev; T. I. Shabatina; G. B. Sergeev. 2009. "Nanosized silver/thiocholesterol aggregates." Moscow University Chemistry Bulletin 64, no. 4: 182-185.
The nanoscale particles of silver and copper coated with amorphous carbon (Ag/C and Cu/C) react with liquid carbon tetrachloride at 25–30°C to selectively form hexachloroethane in 60% yield.
Victor Timoshenko; Alexey V. Bogdanov; Tatyana I. Shabatina; Alexey A. Mysik; Mikhail A. Uimin; Anatoly E. Ermakov; Gleb B. Sergeev. Reaction of carbon tetrachloride with the nanoscale particles of silver and copper in a liquid phase. Mendeleev Communications 2008, 18, 322 -323.
AMA StyleVictor Timoshenko, Alexey V. Bogdanov, Tatyana I. Shabatina, Alexey A. Mysik, Mikhail A. Uimin, Anatoly E. Ermakov, Gleb B. Sergeev. Reaction of carbon tetrachloride with the nanoscale particles of silver and copper in a liquid phase. Mendeleev Communications. 2008; 18 (6):322-323.
Chicago/Turabian StyleVictor Timoshenko; Alexey V. Bogdanov; Tatyana I. Shabatina; Alexey A. Mysik; Mikhail A. Uimin; Anatoly E. Ermakov; Gleb B. Sergeev. 2008. "Reaction of carbon tetrachloride with the nanoscale particles of silver and copper in a liquid phase." Mendeleev Communications 18, no. 6: 322-323.
The main scope of the work is to combine the unique properties of metal atoms, clusters and nanoparticles with different organic and inorganic substances, particularly polymers and liquid crystals using methods of cryochemistry. The joint and layer-by-layer condensation of metal (Ag, Mg, Cu, Pb, Sm and Eu) and different active and inert organic and inorganic compounds vapors on the cooled surfaces at 10–300 K have been made. The problems of stabilization and of activity and selectivity in competitive reactions of metal species are discussed.
Gleb B. Sergeev; Tatyana I. Shabatina. Cryochemistry of nanometals. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2008, 313-314, 18 -22.
AMA StyleGleb B. Sergeev, Tatyana I. Shabatina. Cryochemistry of nanometals. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2008; 313-314 ():18-22.
Chicago/Turabian StyleGleb B. Sergeev; Tatyana I. Shabatina. 2008. "Cryochemistry of nanometals." Colloids and Surfaces A: Physicochemical and Engineering Aspects 313-314, no. : 18-22.
It is shown by IR-Fourier and UV-visible spectroscopy that two biligand complexes of different stoichiometric composition Ln�2L and 2Ln�2L (Ln = Eu; L = 4-pentyl-4′-cyanophenylpyridine) are formed in the course of low-temperature co-condensation of metal and ligand vapors on the surfaces cooled with liquid nitrogen. Quantum-chemical modeling of the equilibrium structures of the mono-and binuclear complexes of europium with unsubstituted cyanophenylpyridyl and para-ethylcyanophenylpyridyl ligands was carried out. The main geometrical parameters of these compounds were determined. For mononuclear complexes, there is a competition between two mechanisms of coordination of the metal atom: formation of sandwich π complexes by interactions with the π orbitals of the aromatic ligand system and σ coordination at the nitrogen atoms of the pyridine ring. The sandwich structures of the binuclear complexes with 4-ethylcyanophenylpyridine are stabilized by N…H intermolecular contacts between the N atom of the cyano group and the terminal H atom of the ethyl group. The spectral shifts and the relative thermal stability of complexes with varying nuclearity are discussed.
T. I. Shabatina; A. V. Vlasov; A. Yu. Ermilov; S. V. Konyukhov; S. V. Nemukhin; G. B. Sergeev. Low-temperature complexes of europium atoms and dimers with cyanophenylpyridines and alkylcyanophenylpyridines. Journal of Structural Chemistry 2007, 48, 765 -773.
AMA StyleT. I. Shabatina, A. V. Vlasov, A. Yu. Ermilov, S. V. Konyukhov, S. V. Nemukhin, G. B. Sergeev. Low-temperature complexes of europium atoms and dimers with cyanophenylpyridines and alkylcyanophenylpyridines. Journal of Structural Chemistry. 2007; 48 (4):765-773.
Chicago/Turabian StyleT. I. Shabatina; A. V. Vlasov; A. Yu. Ermilov; S. V. Konyukhov; S. V. Nemukhin; G. B. Sergeev. 2007. "Low-temperature complexes of europium atoms and dimers with cyanophenylpyridines and alkylcyanophenylpyridines." Journal of Structural Chemistry 48, no. 4: 765-773.