The Accelerated SuFEx Click Chemistry (ASCC) protocol, adapted to a 96-well plate format, has been applied to the late-stage derivatization of bioactive molecules and array synthesis of anticancer agents, showcasing its potential for drug discovery.
The structure and dynamics of an antibody (anti-EGFP VHH), antigen (EGFP) and their complex are studied using circular dichroism, fluorescence correlation spectroscopy and smFRET.
A novel bi-functional liposome delivers docetaxel specifically to melanoma cancer cells targeting integrin (α4β1) and ephrin (EphA2) receptors and enhances the efficacy of docetaxel.
About Me
I am a chemical biologist, working on nucleic acid chemistry, peptide chemistry, and molecular-chemo-genetics research area.
I am a chemical biologist, working on nucleic acid chemistry, peptide chemistry, and molecular-chemo-genetics research area.