Objectives Natural remedies are becoming increasingly popular and important in the public and scientific communities. Historically, natural remedies have been shown to present interesting biological and pharmacological activity and are used as chemotherapeutic agents. For centuries Cordyceps, which is a genus of more than 400 species in the family Clavicipitaceae, has been used in traditional Chinese medicine. This study highlights the chemistry and pharmacology of Cordyceps, especially Cordyceps sinensis (Berk.) Sacc. and C. militaris (Fr.) L. Information was obtained from Google Scholar and the journal databases PubMed and Scopus. Key findings Many bioactive components of Cordyceps have been extracted, such as cordycepin, cordycepic acid, ergosterol, polysaccharides, nucleosides and peptides. Studies show that Cordyceps and its active principles possess a wide range of pharmacological actions, such as anti‐inflammatory, antioxidant, antitumour, antihyperglycaemic, antiapoptosis, immunomodulatory, nephroprotective, and hepatoprotective. Summary More research is required to discover the full extent of the activity of Cordyceps.
Elevated nitrogen (N) deposition alters the terrestrial carbon (C) cycle, which is likely to feed back to further climate change. However, how the overall terrestrial ecosystem C pools and fluxes respond to N addition remains unclear. By synthesizing data from multiple terrestrial ecosystems, we quantified the response of C pools and fluxes to experimental N addition using a comprehensive meta-analysis method. Our results showed that N addition significantly stimulated soil total C storage by 5.82% ([2.47%, 9.27%], 95% CI, the same below) and increased the C contents of the above- and below-ground parts of plants by 25.65% [11.07%, 42.12%] and 15.93% [6.80%, 25.85%], respectively. Furthermore, N addition significantly increased aboveground net primary production by 52.38% [40.58%, 65.19%] and litterfall by 14.67% [9.24%, 20.38%] at a global scale. However, the C influx from the plant litter to the soil through litter decomposition and the efflux from the soil due to microbial respiration and soil respiration showed insignificant responses to N addition. Overall, our meta-analysis suggested that N addition will increase soil C storage and plant C in both above- and below-ground parts, indicating that terrestrial ecosystems might act to strengthen as a C sink under increasing N deposition.