Artificial intelligence (AI) is rapidly reshaping agrifood systems by enabling data-driven, adaptive, and increasingly autonomous approaches across agricultural production, food manufacturing, food-safety monitoring, supply-chain management, and consumer-oriented food services. This review critically examines the expanding role of AI technologies, including machine learning, deep learning, computer vision, generative AI, multimodal foundation models, robotics, digital twins, blockchain, the Internet of Things (IoT), and edge computing, in transforming modern agrifood ecosystems. Recent advances in precision agriculture, intelligent food manufacturing, predictive food-safety systems, AI-driven traceability, and sustainable supply-chain optimization are synthesized while evaluating their technical performance, industrial relevance, and operational outcomes.Current evidence indicates that AI-assisted precision agriculture can reduce irrigation water use by 20–40%, fertilizer application by 15–25%, and pesticide utilization by more than 30% under optimized conditions. Deep-learning-based crop disease detection systems frequently achieve accuracies exceeding 95%, while predictive yield models integrating remote sensing and climatic datasets can approach forecasting accuracies of 85–90%. In food manufacturing, AI-driven process-control systems and computer-vision platforms are improving operational consistency, reducing processing inefficiencies by up to 30%, and strengthening automated quality assessment. AI-integrated food-safety systems combining spectroscopy, biosensors, blockchain, and predictive analytics are further enhancing contamination detection, shelf-life prediction, traceability, and recall management across global supply chains.Despite substantial progress, major challenges remain, including fragmented datasets, interoperability limitations, computational intensity, cybersecurity risks, algorithmic bias, regulatory uncertainty, and unequal access to digital infrastructure. Overall, responsible integration of AI with explainable governance, sustainable computational frameworks, and inclusive digital-transition strategies will be essential for developing resilient, transparent, and environmentally sustainable future agrifood systems.