Since 2005, the decline in HIV incidence has slowed down, and there is a need to optimise prevention services among young people to sustain and accelerate the HIV decline. This study aimed to describe HIV prevention practices among university students in South Africa. The Arksey and O’Malley Framework for conducting scoping reviews was used. South African studies that described the HIV prevention practices among university students, published in English from 2015 to 2025, were included. The search strategy was developed on the 8 December 2024, then on the 7 November 2025, and five databases were searched using key search terms: university students, HIV prevention, and South Africa. Two reviewers selected articles and extracted data using an extraction tool developed by the researchers. Extracted data was analysed using content analysis. Consultation was performed with students, conveniently selected from one university, and data was collected using interviews. Data from these students was analysed using Braun and Clarke’s thematic analysis. Thirteen studies were included in the review. Most (30.8%) were from KwaZulu-Natal province. A total of 15 students aged between 19 and 22 years were consulted. Most (53.3%) students were female. HIV prevention interventions used included HIV testing, which was sub-optimal due to stigma. Students also used condoms, although female condom use was minimal. Biomedical HIV prevention interventions used included post-exposure prophylaxis and pre-exposure prophylaxis, and these were used together with other HIV prevention interventions. Gaps remain to ensure optimal HIV prevention practices, and it is recommended that other biological HIV prevention methods like voluntary medical male circumcision, should be utilised.

Pre-eclampsia affects several physiological systems, often changing the course of pregnancy and manifesting with both maternal and foetal adversities, with a higher burden in rural Sub-Saharan African settings. This study presents maternal and foetal adverse outcomes associated with pre-eclampsia at a rural tertiary hospital in the Eastern Cape Province of South Africa. A prospective analytical case-control study was conducted with 250 pregnant women planned for delivery at the study setting’s labour unit. Pregnant women with pre-eclampsia were considered cases, whereas pregnant women without pre-eclampsia were considered controls. Cases were enrolled first, followed by a matched pair of controls based on their gravidity. A consecutive sampling technique was used to recruit eligible cases and controls. Data was collected using a self-designed questionnaire followed by descriptive and inferential analysis. Adverse foetal outcomes associated with pre-eclampsia were low birth weight [Adjusted odds ratio (AOR) = 2.1, p = 0.006] and foetal distress (AOR = 2.5, p < 0.001). Maternal outcomes associated with pre-eclampsia were haemolysis, elevated liver enzymes, and low platelets syndrome (AOR = 42.7, p < 0.001), as well as preterm delivery (AOR = 3.0, p = 0.001). Early antenatal visits, continuous monitoring of pre-eclamptic pregnant women, and implementation of preventive and curative measures to reduce the possibilities of this condition and its adverse outcomes are needed.