This paper reviews existing literature on digital health innovation ecosystems. It aims to explore the terms digital health, innovation and digital ecosystems to identify components towards presenting a conceptual framework for a digital health innovation ecosystem as part of a larger study. A systematic literature review was conducted on four academic databases: ACM, ScienceDirect, IEEE Xplore and SpringerLink. Due to the dearth in initial search results, the search was broadened to include non-academic publications and practitioner case reports. The study identified components of digital health, components of innovation relevant to the healthcare domain and components of digital ecosystems. It further suggests, within the context, a comprehensive definition of digital health innovation ecosystems. A conceptual framework for digital health innovation ecosystems is proposed. The findings from this study could conceivably be a step towards enabling a common understanding of practitioners, professionals and academics within the digital health domain as well as a basis for further studies on digital health innovation ecosystems

Information and Communication Technology (ICT) solutions (e.g. e-health, telemedicine, e-education) are often viewed as vehicles to bridge the digital divide between rural and urban healthcare centres and to resolve shortcomings in the rural health sector. This study focused on factors perceived to influence the uptake and use of ICTs as e-health solutions in selected rural Eastern Cape healthcare centres, and on structural variables relating to these facilities and processes. Attention was also given to two psychological variables that may underlie an individual's acceptance and use of ICTs: usefulness and ease of use. Recommendations are made with regard to how ICTs can be used more effectively to improve health systems at five rural healthcare centres where questionnaire and interview data were collected: St. Lucy's Hospital, Nessie Knight Hospital, the Tsilitwa Clinic, the Madzikane Ka-Zulu Memorial Hospital and the Nelson Mandela General Hospital.