Roberto Lima de Albuquerque

Dr. Roberto Lima de Albuquerque

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 August 2025 in Journal of Molecular Structure
Verified
Journal Article
Closed access
ASAmanda Santos da Silva
Amanda Santos da Silva
VFVanessa Moreira Frota
Vanessa Moreira Frota
MCMaria Gisele Medeiros Chaves
Maria Gisele Medeiros Chaves
CNCarlos Alberto Chaves Girão Neto
Carlos Alberto Chaves Girão Neto
MFMaria Kueirislene Amâncio Ferreira
Maria Kueirislene Amâncio Ferreira
Helcio Silva Dos SantosHelcio Silva Dos Santos
Helcio Silva Dos Santos

9 September 2025 in Journal of Molecular Structure
Verified
Journal Article
Closed access
CTCíntia Ramos Teixeira
Cíntia Ramos Teixeira
IRIvana Carneiro Romão
Ivana Carneiro Romão
NCNoelia Marcela Ceballos
Noelia Marcela Ceballos
FLFrancisco Nithael Melo Lucio
Francisco Nithael Melo Lucio
MFMarisa Jádna Silva Frederico
Marisa Jádna Silva Frederico
Helcio Silva Dos SantosHelcio Silva Dos Santos
Helcio Silva Dos Santos

17 December 2024 in Divers@!
Verified
Journal Article
Open access
FSFrancisco Ivanildo Simão Da Silva
Francisco Ivanildo Simão Da Silva
RARoberto Lima de Albuquerque
Roberto Lima de Albuquerque
AAAlisson Andrade Almeida
Alisson Andrade Almeida
O estudo de temas de interesse para a sociedade nas aulas de Química é estratégico, pois permite que os alunos compreendam melhor a relação entre os conceitos teóricos e práticos. Por exemplo, o tema biodiesel pode ser utilizado para abordar os processos da química aliados às questões ambientais e sociais. Dessa forma, a presente revisão bibliográfica buscou avaliar os efeitos da introdução do tema biodiesel no ensino de Química de algumas escolas do Ensino Médio. O material bibliográfico foi acessado nas plataformas Google Acadêmico e Periódicos da Capes. Os resultados destacaram os benefícios de se trabalhar o assunto biodiesel em sala de aula com o aumento na compreensão de alguns conceitos químicos, como, por exemplo, a reação de transesterificação; o que resultou no aumento do interesse dos alunos pelo aprendizado e desempenho acadêmico. Isso pode ser associado, provavelmente, a curiosidade do aluno com o mundo que o cerca.

30 July 2025 in Pharmaceutics
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Journal Article
Open access
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MFMaria Kueirislene Amâncio Ferreira
Maria Kueirislene Amâncio Ferreira
FMFrancisco Rogenio da Silva Mendes
Francisco Rogenio da Silva Mendes
EMEmmanuel Silva Marinho
Emmanuel Silva Marinho
RARoberto Lima de Albuquerque
Roberto Lima de Albuquerque
JGJesyka Macedo Guedes
Jesyka Macedo Guedes
Helcio Silva Dos SantosHelcio Silva Dos Santos
Helcio Silva Dos Santos
Background/Objectives: The incorporation of bioactive molecules into mesoporous carriers is a promising strategy to improve stability, solubility, and therapeutic efficacy. In this study, we report for the first time the encapsulation of the synthetic chalcone 4-Cl into KIT-6 mesoporous silica and evaluate its cytotoxicity, toxicological profile, and pharmacological activities (antinociceptive, anti-inflammatory, and anxiolytic) using an in vivo zebrafish (Danio rerio) model. Methods: Zebrafish were orally dosed with 4-Cl, 4-Cl/KIT-6, or KIT-6 (4, 20, 40 mg/kg) and mortality was recorded for 96 h. For analgesia, zebrafish pretreated with 4-Cl, 4-Cl/KIT-6, KIT-6, or morphine received a tail stimulus (0.1% formalin). Locomotor activity (quadrant crossings) was monitored for 30 min to assess analgesia (neurogenic: 0–5 min; inflammatory: 15–30 min). For inflammation, abdominal edema and weight gain were assessed 4 h after intraperitoneal carrageenan (1.5%). Zebrafish (n = 6/group) received 4-Cl, 4-Cl/KIT-6, or KIT-6 (4, 20, 40 mg/kg, p.o.). Controls received ibuprofen (100 mg/kg, p.o.) or 3% DMSO. Weight was measured hourly for 4 h post-carrageenan (difference between baseline and hourly weights). Results: Physicochemical characterizations confirmed successful encapsulation without compromising the ordered structure of KIT-6, as evidenced by a significant reduction in surface area and pore volume, indicating efficient drug incorporation. In vivo assays demonstrated that the 4-Cl/KIT-6 formulation maintained the pharmacological activities of the free chalcone, reduced toxicity, and, notably, revealed a significant anxiolytic effect for the first time. Conclusions: These findings highlight KIT-6 as a promising platform for chalcone delivery systems and provide a solid basis for future preclinical investigations.

17 September 2025 in Journal of Molecular Structure
Verified
Journal Article
Closed access
BOBruna Rocha de Oliveira
Bruna Rocha de Oliveira
RARoberto Lima de Albuquerque
Roberto Lima de Albuquerque
MFMaria Kueirislene Amâncio Ferreira
Maria Kueirislene Amâncio Ferreira
JMJéssica Bezerra Maciel
Jéssica Bezerra Maciel
JGJesyka Macedo Guedes
Jesyka Macedo Guedes
HSHélcio Silva dos Santos
Hélcio Silva dos Santos

28 January 2024 in Revista E-Tech: Tecnologias para Competitividade Industrial - ISSN - 1983-1838
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JNJanielly Paixão Barroso Nobre
Janielly Paixão Barroso Nobre
DSDarlane Wellen Freitas Soares
Darlane Wellen Freitas Soares
RARoberto Lima de Albuquerque
Roberto Lima de Albuquerque
JJJosé Milton Ferreira Junior
José Milton Ferreira Junior
In the textile industry, the processing of fibers and the application of dyes require high water consumption, producing high rates of industrial waste. Dyes, in turn, have great stability, which can result in highly contaminated effluents. If disposed of incorrectly, this waste can cause serious problems to the environment and human health. In this sense, it is essential to decontaminate these effluents before releasing them into water bodies. To this end, the adsorption process has proven to be very effective in removing dyes from wastewater in the textile sector. Aiming at the optimization and economic viability of this process, this investigation focuses on the use of an agro-industrial residue, the silver banana peel (Musa paradisiaca), as an alternative biosorbent. Based on an experimental and applied methodology, tests to determine pH were applied in order to determine the most suitable pH for the procedure. Variations in adsorbent concentrations were also evaluated to obtain the best use of the material in removing the methylene blue dye. The results obtained in the biosorption tests indicated 99.5% removal, demonstrating high efficiency in the process. In this way, the silver banana peel (Musa paradisiaca) presented itself as an efficient biosorbent in the adsorption of methylene blue dye, becoming a sustainable and low-cost alternative.