Enas Sameer Magharbil

Dr. Enas Sameer Magharbil


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 July 2025 in Genes
Verified
Journal Article
Open access
PDF file
Mariam Mohammed Ali AlEissaMariam Mohammed Ali AlEissa
Mariam Mohammed Ali AlEissa
AAAbrar Ali Alhawsawi
Abrar Ali Alhawsawi
RARaghad Harran Alonazi
Raghad Harran Alonazi
EMEnas Sameer Magharbil
Enas Sameer Magharbil
AAAbeer Aljahdali
Abeer Aljahdali
MMMoustafa Magliyah
Moustafa Magliyah
Gene therapy has emerged as a promising treatment for several eye diseases since it may restore vision and stop blindness. Many eye diseases, including retinitis pigmentosa and macular degeneration, have historically been rather difficult to treat and usually cause permanent vision loss. However, thanks to advances in gene therapy, many disorders can now be effectively targeted and genetically changed, providing a safer, more direct, maybe even curative approach. By introducing, altering, or repairing specific genes inside the eye, gene therapy seeks to fix the defective genes causing these disorders, thereby improving general eye health and visual ability. Voretigene neparvovec is one FDA- and EMA-approved treatment for RPE65 mutations. Retinitis pigmentosa, age-related macular degeneration, X-linked retinoschisis, choroideremia, and Stargardt disease are among the several eye disorders still under clinical trials, and experimental treatment is in progress. As research on gene therapy develops, it opens the path for groundbreaking treatments that could fundamentally change the ophthalmic care scene.