Mirthala Flores-García, PhD, is a Biomedical Researcher in the Department of Molecular Biology at
the Instituto Nacional de
Cardiología Ignacio Chávez. Her research
integrates cardiovascular pharmacology, molecular biology, and translational
medicine to investigate the mechanisms regulating platelet function,
thrombosis, and cardiometabolic risk.
Her work has focused on the pharmacological modulation of
platelet aggregation and the identification of bioactive molecules with
potential antiplatelet and antithrombotic properties. Early studies examined
the influence of environmental exposures on cardiovascular pathology and
thrombotic risk. Subsequent research addressed the discovery and
characterization of novel compounds capable of modulating platelet activation
and thrombin generation, including copper-based complexes and naturally derived
bioactive molecules that inhibit platelet aggregation without significantly
altering coagulation pathways.
More recently, her research has expanded toward molecular
and translational approaches to cardiovascular disease, including the study of
circulating biomarkers such as microRNAs and extracellular vesicles
(microvesicles and exosomes) involved in vascular dysfunction and
cardiometabolic disorders. Her work has also contributed to the identification
of genetic and transcriptomic factors associated with peripheral artery
disease, providing insights into molecular pathways underlying vascular
pathology and thrombotic complications
Mirthala Flores-García, PhD, is a Biomedical Researcher in the Department of Molecular Biology at
the Instituto Nacional de
Cardiología Ignacio Chávez. Her research
integrates cardiovascular pharmacology, molecular biology, and translational
medicine to investigate the mechanisms regulating platelet function,
thrombosis, and cardiometabolic risk.
Her work has focused on the pharmacological modulation of
platelet aggregation and the identification of bioactive molecules with
potential antiplatelet and antithrombotic properties. Early studies examined
the influence of environmental exposures on cardiovascular pathology and
thrombotic risk. Subsequent research addressed the discovery and
characterization of novel compounds capable of modulating platelet activation
and thrombin generation, including copper-based complexes and naturally derived
bioactive molecules that inhibit platelet aggregation without significantly
altering coagulation pathways.
More recently, her research has expanded toward molecular
and translational approaches to cardiovascular disease, including the study of
circulating biomarkers such as microRNAs and extracellular vesicles
(microvesicles and exosomes) involved in vascular dysfunction and
cardiometabolic disorders. Her work has also contributed to the identification
of genetic and transcriptomic factors associated with peripheral artery
disease, providing insights into molecular pathways underlying vascular
pathology and thrombotic complications