Background. In children with intellectual disability (ID), the acquisition of reading skills constitutes a basic step towards the possibility of independent living, social inclusion and participation. Methods. We carried out a narrative review of the literature on reading fluency and accuracy of individuals with ID resulting from different genetic syndromes (Fragile X, Williams, Velocardiofacial, Prader-Willi, and Down syndrome). Our aim was to define their reading profiles in light of the dual-route reading model. For this purpose, studies that examined both word and non-word reading in children with ID were included in the analysis. Results. Seventeen studies emerged based on the selection criteria. The results were different depending on the control group used. A deficit in reading non-words emerged in studies that used the reading-level match design but not when standardized scores were used, when controls were age-matched or when a mental age matching was used. Thus, a deficit in reading non-words emerged only in studies that used the reading-level match design. However, severe methodological criticisms were recently raised about the use of this matching design. Conclusions. In view of the methodological problems in using grade equivalents, it is premature to draw definite conclusions about the reading profile of children with ID resulting from different genetic syndromes. In any case, the reviewed evidence provides little support for the idea that children with ID have selective difficulty in phonological reading. Thus, the reading profile of children with ID remains an open question that needs to be investigated by means of methodologically sound research.

We report the second case, to the best of our knowledge, of a mother with Prader–Willi syndrome (PWS) who gave birth to a daughter with Angelman syndrome (AS). The menarche occurred when she was 16, and the following menstrual cycles were irregular, but she never took sexual hormone replacement therapy. At the age of 26, our patient with PWS became pregnant. The diagnosis was confirmed by molecular genetic testing that revealed a ~5.7 Mb deletion in the 15q11.1–15q13 region on the paternal allele in the mother with PWS and the maternal one in the daughter with AS, respectively. Both the mother with PWS and the daughter with AS showed peculiar clinical and genetic features of the two syndromes. Our case report reaffirms the possible fertility in PWS; therefore, it is very important to develop appropriate socio-sexual education programs and fertility assessments in order to guarantee the expression of a healthy sexuality.

Background: A substantial proportion of children with autism spectrum disorder (ASD) also have an intellectual disability (ID). However, the academic achievement levels of students with ASD and ID (ASD-ID) are poorly documented and known. Method: We systematically reviewed studies on school skills (reading, spelling, and math) in children and adolescents with ASD-ID. The search was conducted in seven bibliographic databases: Embase, Pubmed/MEDLINE, PsycINFO, Cochrane Library, Ebscohost, Proquest, and Scopus until 28 May 2022. Results: We identified 33,750 reports, four of which met the inclusion criteria for the review. The studies, characterized by Level III evidence (non-randomized controlled trials), included 535 students, 266 in the ASD-ID group and 269 in the ASD-no ID group. A random-effects model meta-analysis revealed that students with ASD-ID had significantly lower reading, spelling, and math scores than students with ASD-no ID. The effect sizes associated with reading score differences were large, although with significant heterogeneity; similarly, the effect sizes associated with spelling and math score differences were also large, although to a lesser extent than for reading. Conclusions: The co-presence of ASD and ID is associated with significant deficits in reading, spelling, and math. However, the present meta-analytic results rest on a limited number of studies. This contrasts with the substantial proportion of children with ASD who have ID and highlights the need for further research to fill a significant gap regarding the profile of academic abilities of students with ASD-ID.

Background: Savant syndrome is a rare condition, in which persons with serious intellectual disabilities demonstrate extraordinary capacities or abilities in contrast to their overall disability. This paper presents the savant abilities of a child with autism spectrum disorder, who showed exceptional arithmetic skills and higher word decoding ability. Methods: A protocol of academic skills evaluation was administered. Assessment of calculation skills included tests on written calculations; numerical knowledge indicating the semantic, syntactic and lexical level; and accuracy and speed measurement. Results: Performances in number elaboration showed an adequate access to semantic and verbal number information. In the written and mental calculation task and in fact retrieval, implicating calculation strategies and information retrieval, processes were automatized. Conclusions: The data gathered show that the child’s performance both for number elaboration and calculation procedures is higher than the school grade attended, typical of people with exceptional abilities.

The Montessori method was originally developed from an examination of children with cognitive disabilities. Numerous studies have explored the application of Montessori principles with typically developing children and adolescents across different educational settings. However, despite its original interest in children with cognitive disabilities, there has been a limited number of systematic reviews specifically addressing its impact on these children. We conducted a systematic review of quantitative research based on a search of the literature on the effects of the Montessori educational approach in teaching academic and non-academic skills to children and young people with intellectual disabilities (IDs) and autism. A search was conducted of seven bibliographic databases: Embase, PubMed/MEDLINE, PsycINFO, Cochrane Library, Ebscohost, Proquest, and Scopus, until 31 October 2024. We identified 7165 reports, 3 of which meet the inclusion criteria for the review. The selected studies reported improvements in the areas investigated, including motor skills, perceptual abilities, cognitive development, and self-care, confirming the effectiveness of the Montessori methodology. Although there are few experimental studies available, these findings provide valuable operational insights. They suggest that we can return to the roots of the method, which was originally designed for children with mental disorders. An experimental approach to this time-honored method could enhance its application in neurodevelopmental disorders, maximizing autonomy and inclusion while improving the quality of life for individuals with disabilities.