This work reviews the authors’ choice of recently published papers where at least one asymmetric quaternary stereocenter has been formed via organocatalysis. The scope and limitations of the reactions are highlighted. 1 Introduction 2 Alkylation and Arylation Reactions 3 Addition to Carbon-Carbon Multiple Bonds 4 Addition to N=X Double Bonds 5 Nucleophilic Aziridine-Ring Opening 6 Aldol and Related Reactions 7 Brønsted Acid Organocatalyzed Formation of Nitrogen-Containing Quaternary Stereocenters 8 Halogenation and Pseudohalogenation Reactions 9 Epoxidation 10 Diels-Alder Reaction 11 N-Heterocyclic Carbene Catalysis 12 Cascade Reactions 13 Conclusion and Outlook