Francesca Romana Centini

Ms. Francesca Romana Centini

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 May 2026 in Journal Of Neuroradiology
Verified
Journal Article
Closed access
LCLeonardo Di Cosmo
Leonardo Di Cosmo
FCFilippo Emanuele Colella
Filippo Emanuele Colella
PŁPaweł Łajczak
Paweł Łajczak
ESEdoardo Schifino
Edoardo Schifino
SCSantiago Nieto Cuervo
Santiago Nieto Cuervo
BSBruno Fernandes de Oliveira Santos
Bruno Fernandes de Oliveira Santos

Verified
Journal Article
Open access
PDF file
LCLeonardo Di Cosmo
Leonardo Di Cosmo
SCSantiago Nieto Cuervo
Santiago Nieto Cuervo
Francesca PellicanòFrancesca Pellicanò
Francesca Pellicanò
FCFrancesca Romana Centini
Francesca Romana Centini
JCJad El Choueiri
Jad El Choueiri
Alessio BaricichAlessio Baricich
Alessio Baricich
Background and Objectives: Recent technological advances have introduced new interventions in the field of stroke rehabilitation. Among them, visual feedback (VF) and non-invasive brain stimulation (NIBS) have gained considerable attention, with growing evidence supporting their efficacy. However, their combined application in lower limb recovery remains to be established. This systematic review aims to evaluate the current evidence on the therapeutic effect of combining VF and NIBS for lower limb motor rehabilitation in stroke patients. Methods: Following PRISMA guidelines, PubMed, Embase, Scopus, and Cochrane databases were searched for randomized controlled trials and observational studies comparing VF and NIBS interventions with either their monotherapy, placebo, or standard treatment. The outcomes evaluated for lower limb function included balance, gait, and motor performance. Results: From 997 studies screened, 5 studies (3 RCTs and 2 cohort studies) were included. Despite heterogeneity in the immersion level, NIBS protocols, and outcome measures, evidence emerged supporting the efficacy of combined VF and NIBS across multiple outcomes. However, the degree to which these interventions outperform standard therapies remains uncertain, primarily due to a limited number of comparator studies and the quality of the existing data. Conclusions: This review provides preliminary insights into the potential of combining VF and NIBS in stroke patients affected by lower limb motor impairments. Future research should focus on standardizing protocols and addressing demographic variability to enhance the reliability and comparability of findings.